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{
"caption": "Transmission Electron Microscopy of thin sections of the U(VI) reducing strains DL1 (A and C) and MacA (B and D) before (A, B) and after (C, D) treatment with bicarbonate and air. Bar represents 1 μm",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1829397-4-1471-2180-7-16-3.jpg"
} | 001000 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Transmission Electron Microscopy of thin sections of U(VI) reducing G. sulfurreducens. A, B and C. Periplasmic uranium accumulation by various strains of G. sulfurreducens: A – wild type (DL1), B – DLMC5 (U(VI) reduction is inhibited 60%), C – DL1-MacA (U(VI)-reduction is inhibited completely). OM – outer membrane, P – periplasm, IM – inner membrane. Bar represents 0.1 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1829397-6-1471-2180-7-16-5.jpg"
} | 001001 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Upper panel: Osteogenic differentiation of MSC after passage 2 (A, B) and passage 10 (C, D). Alizarin Red S staining and Alkaline phosphatase assay were performed after 21 days of osteogenic induction (d21).100× magnification. Middle Panel: Morphological alterations during osteogenesis determined by microscopy on the day of induction (d0), day 4, 7, 14 and 21 after induction. All pictures are shown in 100× magnification. Lower Panel: Adipogenic differentiation of MSC in passage 10 characterized by Oil red O staining; (A) MSC not induced, undifferentiated; (B) MSC 21 days after induction with adipogenic medium 100× magnification.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1829400-4-1471-2164-8-70-1.jpg"
} | 001002 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "A Gallery of Primary Human MDM Infected with HIV-1 Strains YU-2 and Ba-LCells were infected with HIV-1 strain Ba-L (A–C, E, F, and H–J) or YU-2 (D, G, and K).(A–C) Shows plastic-embedded sections displaying extra- and seemingly intracellular virions and budding profiles (open arrows).(D–K) Thawed cryo-sections were labeled with anti-capsid followed by 10 nm (D–G, J, and K) or 5 nm (H and I) protein A gold.(D and E) Labeled virions accumulated inside vacuolar structures.(F) Labeled virions in a plasma membrane invagination that is directly connected to the extracellular space.(G) A virus-budding profile (open arrow) and several virus particles on the plasma membrane.(H) A virus-budding profile (open arrow) next to a structure resembling a clathrin-coated pit (arrow) inside a vacuolar structure.(I) A virus-containing vacuole with a structure resembling a clathrin-coated pit (arrow).(J and K) Virus-budding profiles (open arrows) next to structures resembling clathrin-coated pits (arrows) on the cell surface. PM, plasma membrane. Bar, 200 nm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1829407-2-ppatp0030036pg001.jpg"
} | 001003 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "RR Staining of Uninfected MDM Reveals a Complex Plasma Membrane OrganizationMDM were fed with BSA-gold and fixed in the presence of RR.(A) A cell profile at low magnification contacting a neighboring cell. The smooth left side was previously attached to the substrate (indicated as “bottom”); the right side displaying many RR-positive protrusions is the side facing the extracellular medium (“top”). Seemingly intracellular structures also appear RR-positive. At the tight-fitting contact zones between two cells (arrows) the stain appears more electron-dense than on single lipid bilayers.(B) Higher magnification of the boxed area in (A) showing the collection of vacuolar-like invaginations stained with RR.(C) Higher magnification of the boxed area in (B) showing a RR-positive structure next to a BSA-gold-filled endosome (arrowhead).(D) Comparison of RR-positive cell surface protrusions and similar RR-positive protrusions, which appeared intracellular in this section. Arrowheads indicate gold-filled endosomes. The inset in (D) shows an enlargement of a BSA-gold-filled endosome in the boxed area.(E) Two identical looking structures with stacked protrusions; in the upper one the membranes are not RR-stained, indicating that not all vacuolar structures are accessible to the stain.(F) A collection of BSA-gold-filled endosomes (arrowheads) next to RR-stained vacuolar structures to emphasize the differences in size and morphology. The inset in (F) shows an enlargement of a BSA-gold-filled endosome in the boxed area. Nu, nucleus. Bars, 2 μm (A and B) and 500 nm (C–F).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1829407-3-ppatp0030036pg002.jpg"
} | 001004 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Localization of CD63 and CD44 in HIV-1-Infected MDMHIV-1 strain Ba-L-infected MDM were fed with 10 nm BSA-gold (except in G) for 2 h before fixing. Thawed cryo-sections were single-labeled with anti-CD63 (A and B, 15 nm gold) or anti-CD44 (F, 15 nm gold); or double-labeled with anti-capsid (C–E, G, and H, 5 nm gold) and anti-CD63 (C–E, 15 nm gold); or anti-CD44 (G, 10 nm gold and H, 15 nm gold).(A) CD63 (arrows) on endosomes efficiently filled with BSA-gold and on tubular vesicular membranes nearby.(B) CD63 (arrows) on plasma membrane protrusions of two adjacent cells.(C) A virus-budding profile labeled for anti-capsid (5 nm gold, open arrows) and anti-CD63 (15 nm gold) at the plasma membrane.(D and E) Virions inside vacuolar structures, labeled with anti-capsid (5 nm), are significantly labeled with anti-CD63. The inset in (D) shows the enlargement of double-labeled virions in the boxed area of (D). CD63 also localizes to BSA-gold-filled endosomes (arrowheads in E). Note that the virus-filled structure in (E) is devoid of 10 nm BSA-gold and displays a structure that resembles a clathrin-coated pit (small arrow).(F) CD44 at the plasma membrane.(G and H) CD44 on virions and on a budding profile (open arrow in G). The inset in (H) is an enlargement of the boxed area in (H) and shows several double-labeled virions inside a vacuolar structure.Note that CD44 is excluded from BSA-gold-filled endosomes (arrowheads in F and H). PM, plasma membrane. Bars, 200 nm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1829407-4-ppatp0030036pg005.jpg"
} | 001005 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "HIV-1 Buds and Accumulates in RR-Stained Domains(A) Flow diagram of macrophage differentiation, infection, and processing for EM. CA, capsid protein.(B) Low magnification profile of an infected MDM displaying RR stain on the cell surface and on seemingly intracellular plasma membrane invaginations (arrows). Note that the bottom surface (indicated as “bottom”) that was previously attached to the substrate is not RR-stained, whereas the top surface is. The inset shows a mature virus particle on the tip of a finger-like plasma membrane protrusion.(C) Collection of RR-stained protrusions with RR-stained mature virus particles.(D) Large cell-surface invagination that is directly connected to the RR-stained cell surface and contains numerous RR-stained virions. The inset shows a multivesicular BSA-gold-filled endosome inside the same cell.(E and F) RR-stained vacuole-like structures harboring virus particles and displaying structures resembling clathrin-coated pits (small arrows). Arrowheads in (E) indicate gold-filled endosomes that are not RR-stained and significantly smaller than the virus-filled structures.(G) RR-stained virus particles accumulating between the RR-stained plasma membranes of two neighboring cells; arrowheads, BSA-gold-filled endosomes. The inset in (G) shows an enlargement of a BSA-gold-filled endosome in the boxed area.(H–K) Virus-budding profiles (open arrows) (H) on the RR-stained cell surface and (I) on a RR-stained cell surface invagination.(J) Early virus bud on the tip of a finger-like protrusion in a vacuolar structure devoid of RR and BSA-gold.(K) Late virus buds on RR-negative membranes next to BSA-gold-filled endosomes (arrowheads). Nu, nucleus; PM, plasma membrane. Bars, 2 μm (B–D) and 500 nm (E–K).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1829407-6-ppatp0030036pg003.jpg"
} | 001006 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Phagocytosis in eiger MutantsWeek-old male flies were injected with FITC-labeled dead S. aureus and allowed to phagocytose the particles and then were injected with Trypan blue to quench extracellular fluorescence. The dorsal abdomen of the fly was photographed under epifluoresence optics. Anterior is on the left. (A) Wild-type fly (w1118); (B) eiger mutant fly (w1118; egr1/egr3). Bright spots indicate hemocytes that have phagocytosed the S. aureus. The pictures are representative of the 15 flies examined for the experiment.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1829408-1-ppatp0030041pg004.jpg"
} | 001007 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "MCHL H/RS cells in an inflammatory background, H&E × 40.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831464-0-1746-1596-2-10-1.jpg"
} | 001008 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "MCHL: strong nuclear Bob-1 staining in all H/RS cells, Bob-1 immunostaining, DAB, Hx, × 40.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831464-1-1746-1596-2-10-2.jpg"
} | 001009 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "MCHL: LMP-1 immunostaining of the same case, DAB, Hx, × 20.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831464-2-1746-1596-2-10-5.jpg"
} | 001010 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "MCHL: strong nuclear EBV staining, EBER-ISH, BNCT, Hx, × 20.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831464-3-1746-1596-2-10-4.jpg"
} | 001011 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "MCHL: higher power magnification of the previous figure, Bob-1 immunostaining, DAB, Hx, ×100.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831464-4-1746-1596-2-10-3.jpg"
} | 001012 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Effects of chlorine on epithelial cell proliferation. Panel A. Representative pictures showing PCNA immunostaining in airway epithelial cells before (a) and 1 day after exposure to 400 ppm Cl2 gas (b) in wild type mice. Panel B. Numbers of epithelial cells with positive staining for PCNA per mm of basement membrane. Knockout mice have impaired epithelial cell regeneration following Cl2 gas injury. The vertical bars indicate one SEM. * P < 0.05 compared to 0 ppm control.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831470-3-1465-9921-8-21-3.jpg"
} | 001013 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Echocardiogram showing apical collection of fluid in the pericardial space (white arrow).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831473-0-1471-2334-7-12-1.jpg"
} | 001014 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Immunochemical detection of p16INK4a in cervical carcinoma and cervical cancer cell lines. Cervical cancer cell lines: a – C4-I; b – SiHa; c – CaSki; primary carcinomas (numbers are indicated as on fig. 1, 2 and table 1): d – case 2, e – case 6, f – case 7, g – cervical epithelium adjacent to tumor. Original magnification: a-f × 40; g × 20.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831478-1-1471-2407-7-47-3.jpg"
} | 001015 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Nissl-stained ganglion cell layers from control and experimental eyes. Each panel is representative of the mid-central superior retina of the inbred lines shown. Two weeks after optic nerve crush, the retinas exhibit a loss of cells with larger somas and nuclei with prominent nucleoli, features characteristic of retinal ganglion cells. DBA/2J, SJL/J, and BALB/cByJ mice exhibit resistant, moderately resistant, and susceptible phenotypes to optic nerve crush, respectively. Magnification 200×.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831479-2-1471-2202-8-19-2.jpg"
} | 001016 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Localization of KCa channels in brain tumor tissues from xenogenic rat model and patients of lung cancer brain metastases. KCa channels (green) were localized in the endothelial cells of capillaries (red) in the tumor mass (A). In the contralateral side of brain, much less of KCa channel was detected in normal brain. (B). KCa channels are co-localized with von Willebrand factor, a marker of endothelial cells, in human tumor tissue of lung cancer brain metastases (C). Scale bar = 250 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831484-0-1476-4598-6-22-6.jpg"
} | 001017 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Expression of KCa channels and B2R in CRL-5904 cells and HBMEC. KCa channels (green) distributed in CRL-5904 cells (A~C) and HBMEC (G~I). The B2R (green) were expressed in CRL-5904 cells (D~F) and HBMEC (J~L). Cells were located by counterstaining with DAPI (blue, B, E, H, K) and merged images are also shown (C, F, I, L). Scale bar = 50 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831484-3-1476-4598-6-22-3.jpg"
} | 001018 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Expression of KCa channels and B2R in the lung cancer metastatic brain tumor tissue from patients. KCa channels (A) and B2R (B) expression were detected on the tumor cells in the tissue. Negative control experiments of KCa channels (C) and B2R (D) did not show specific staining on the corresponded specimens by deleting of primary antibodies. Scale bar = 50 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831484-4-1476-4598-6-22-2.jpg"
} | 001019 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Immunohistochemistry analysis of nidogen-2 expression in human colon carcinomas. (A) Sample 3405, a moderately differentiated adenocarcinoma that does not present aberrant methylation of the NID2 gene promoter, shows a strong immunoreactivity for nidogen-2 in the stroma. (B) Sample 3413, a poorly differentiated adenocarcinoma that presents aberrant methylation of the NID2 gene promoter, shows a nearly complete lack of immunoreactivity for nidogen-2. (Original magnification, 200×).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831485-1-1476-4598-6-17-5.jpg"
} | 001020 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Immunostaining of SPANX-N (a, b) and the negative control (c, d) at low (a, c) and high magnification (b, d) on normal human testis sections (bars indicated). The staining is clearly specific for late spermatids and spermatozoa (in pink, a, b). Autofluorescence (i.e., non-specific signal, a, b) is also detectable in red blood cells and can be recognized by the overlapping signals in the green and red wavelengths. Nuclei are counterstained with DAPI (in blue).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831492-10-ponep0000359pg005.jpg"
} | 001021 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Immunocytochemical detection of SPANX-N in the melanoma cell line. 938MEL melanoma cell line (green; middle and right panels); co-immunostaining for the cell multiplication marker Ki67 (red; left and right panels; overlap with SPANX-N appears as yellow). Upper panels show the test samples, whereas bottom panels provide the negative control for SPANX-N (primary antibody omitted).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831492-5-ponep0000359pg007.jpg"
} | 001022 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "OLIG1 Immunohistochemistry on a Lung Tissue Array\nOLIG1 immunohistochemistry on (A and E) tumor-free lung, (B) an OLIG1 negative adenocarcinoma, and (F) an OLIG1 negative SCC; (C) a low OLIG1 expressing adenocarcinoma and (G) a low OLIG1 expressing SCC are shown; (D) a high OLIG1 expressing adenocarcinoma and (H) a high OLIG1 expressing SCC are shown. All images were acquired at 400× magnification.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831740-3-pmedp0040108pg005.jpg"
} | 001023 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Full-field 2-D projection images created using phase-contrast synchrotron x-rays. Images were chosen to highlight the highest quality imagery currently obtainable (a, b) and corresponding stills from live video (c-l). (a) Carabid beetle (Pterostichus stygicus) in dorsoventral view with legs removed and sacrificed prior to imaging. Image is a high-resolution composite of multiple images. The air-filled tubes of the tracheal system can be prominently seen. The dark spots on the left side, mid-body are soil particles on the outer surface of the elytra. (b) Close-in view of one section of the prothorax, showing the branching pattern of tracheae. (c, d) One half-cycle of rhythmic tracheal collapse in a live carabid beetle (Platynus decentis) in dorsoventral view. Images are frame grabs from a video recording (See Additional file 1); time interval is 0.5 s. Total time of collapse and reinflation of the tubes is 1.0 s. (e-l) Visualization of internal food movement using labeled markers. (e) Schematic of the head and thorax of a butterfly (Pieris rapae) in lateral view. The foregut is shown in red; the square highlights the region of video stills in (f-h), and black arrow indicates the direction of food movement. (f-h) Video stills of passage of a food bolus posteriorly through the esophagus, moving through the frame from upper right to lower left (see Additional file 2). Red arrows indicate the leading (f) and trailing (h) edges of the bolus. Interval between frames is 0.5 s. Food is sugar water/iodine mixture. X-ray energy (33.2 keV) was tuned to just above the K-edge absorption band for iodine. (i) Schematic of a carabid beetle (Pterostichus stygicus) in dorsoventral view (legs removed). Circular structures in mid-body represent coxae; the gut is represented in gray and red. Square highlights video in (j-l), visualization of cadmium-laced food in the foregut (see additional file 3). Video stills (j-l) show movement of gut including anterior-posterior translation and squeezing of the crop (cr) and translation and rotation of the proventriculus (pr). The proventriculus is a valve that leads to the midgut [41]; here, it is closed. Note that only parts of the gut with contrast agent can be seen. Interval between frames: j-k, 2 s; k-l, 6 s. X-ray energy, 25 keV. Scale bars: a,b, 1 mm; c,d, 200 μm; f-h, 200 μm; j-l, 1 mm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831761-5-1741-7007-5-6-1.jpg"
} | 001024 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Human clinical cases (from the top to the bottom). Augmentation cases: (A-D): Augmentation of extraction socket upon extraction of tooth # 8. (E-H): Ridge augmentation therapy in area of teeth # 5–6. (I-L): Sinus augmentation therapy (induced bone formation within the right maxillary sinus) prior insertion of a titanium implant in area of teeth # 3–4. Preservation cases: (M-P): Regeneration of bone around the exposed threads of a titanium implant positioned in area of tooth # 9. (Q-T): Regeneration of bone around a titanium implant in position of tooth # 30 affected by peri-implantitis.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831762-0-1479-5876-5-13-6.jpg"
} | 001025 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Heterotopic (muscle) bioassay in ferrets: (A): The biceps femoris of a ferret is shown. A sample of CS-Platelet and a sample of CS were implanted in the muscle tissue. (B): Four weeks after implantation the x-ray evaluations showed the presence of radio-opaque formations only in correlation with the implantations of CS-Platelet. (C, E-H): At the histological evaluation, the radio-opaque formation appeared as an ossicle formed by trabecular bone. (D, I-L): No bone formation was observed in correspondence with the implantations of Calcium Sulfate alone. Hematoxylin and Eosin staining.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831762-4-1479-5876-5-13-2.jpg"
} | 001026 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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{
"caption": "Non-human primate orthotopic (bone) bioassay – Histology. (A-D): samples of alveolar bone implanted with DFDBA. (E-H): Samples of alveolar bone implanted with CS-Platelet. All grafted sites, whether implanted with CS-Platelet or with DFDBA, showed regeneration of trabecular bone. In the sites grafted with DFDBA some residual biomaterial was still visible (B, black arrows). Hematoxylin and Eosin staining. (A and E, 40× original magnification). (B-D and F-H, 100× original magnification).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831762-5-1479-5876-5-13-5.jpg"
} | 001027 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Panel of representative phase contrast micrographs of HFL-1 cells after 24 hours of CSE incubation. A) Untreated Control; B) 1% CSE; C) 2% CSE; D) 5% CSE; E: 10% CSE; F: 20% CSE. Magnifications 20×.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831768-4-1465-9921-8-23-1.jpg"
} | 001028 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Humanoid abdominal/pelvic phantom.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831769-4-1471-2342-7-5-1.jpg"
} | 001029 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Alterations in cellular and mitochondrial morphology induced by tBHP. (A) DIC images from untreated cells, showing normal membrane morphology. (B) Laser scanning confocal microscopy image from untreated cells showing triple labeling with Hoechst 33342 (blue), calcein (green) and TMRM (red). (C, D) Laser scanning confocal microscopy showing the fluorescence of the three dyes followed with the time, (C) 45 min, and (D) 90 minutes, after treatment with 80 μM tBHP. (E) Magnification of the cell indicated by an arrow in panel C and (F) magnification of the cell indicated by an arrow in panel D. (G) DIC images from H9c2 cells treated with 25 μM tBHP for three hours. (H) Laser scanning confocal microscopy (LSCM) image from cells treated with 25 μM tBHP during three hours. Images are representative from 3 different cell preparations. Panels B-D and G, H are the same magnification. Scale bar corresponds to 20 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831770-1-1471-2121-8-11-3.jpg"
} | 001030 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "tBHP induces the translocation of phosphatidylserine to the outer leaflet of the cellular membrane. (Top panel) After treatment with 0, 50 and 100 μM tBHP, for 1 hour, H9c2 cell were labeled with Annexin V and propidium iodide. Left panels: DIC images of H9c2 cells, treated with 0, 50 and 100 μM tBHP. Right panels: corresponding epifluorescence microscopy images of propidium iodide (red) and Annexin V (green). Images are representative from 3 different experiments. All images are the same magnification; scale bar = 20 μm. (Bottom panel) Statistical analysis of the population of control cells or cells treated with increasing concentrations of tBHP, showing the relation between treatment and annexin V/propidium iodide labeling. Analysis was performed by counting cells without labeling (healthy cells), annexin V labeling (apoptotic cells) and PI/Annexin V double labeling (necrotic cells). Data represent the mean ± SEM of 3 different cell preparations.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831770-3-1471-2121-8-11-5.jpg"
} | 001031 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "tBHP induced and increase intracellular oxidative stress in H9c2 cells. (Top panel) H9c2 cells were exposed to 0 (panel A-B) or 50 μM tBHP (panel C-D) for 1 hour. Increase in intracellular oxidative stress was detected by oxidation of dichlorofluorescein. Fluorescence observed in panel B and D is proportional to the degree of oxidation. The corresponding DIC images can be observed in panels A and C. Images are representative from 3 different cell preparations. A-D are the same magnification; scale bar in A = 20 μm. (Bottom panel) Quantification of cell DCF fluorescence intensity. Four different fields were analyzed in each experiment. Data represents the mean ± SEM of 3 different cell preparations. *p < 0.05 vs control.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831770-5-1471-2121-8-11-1.jpg"
} | 001032 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Coronal section of T1 weighted MRI demonstrating complete removal of the left-sided T1-neuroma from the T1-2 intervertebral foramen and from the pulmonary apex.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831774-0-1749-7221-2-7-7.jpg"
} | 001033 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Pre-operative chest X-ray demonstrating a round shadow of approx. 5 cm in diameter in the left pulmonary apex.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831774-1-1749-7221-2-7-1.jpg"
} | 001034 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Post-operative chest X-ray demonstrating removal of the T2 and T3 transverse processes, and proximal parts of the second and third ribs.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831774-2-1749-7221-2-7-6.jpg"
} | 001035 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Transverse section of T2 weighted MRI demonstrating complete removal of the neuroma from the left T1-2 intervertebral foramen and the spinal canal.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831774-3-1749-7221-2-7-8.jpg"
} | 001036 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Coronal section of T1 weighted MRI demonstrating the left pulmonary apex tumor with extension into T1-2 intervertebral foramen.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831774-6-1749-7221-2-7-3.jpg"
} | 001037 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Transverse section of T1 weighted MRI demonstrating protrusion of the tumor from the left T1-2 intervertebral foramen to the spinal cord.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_107-PMC1831774-7-1749-7221-2-7-4.jpg"
} | 001038 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "(A) Endoscopic view of the implanted Polyflex stent showing incomplete sealing of the esophagus lumen (arrows). (B) Complete closure of the anastomotic leakage was obtained by covered colorectal stent (Hanarostent).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1831780-1-1471-230X-7-10-2.jpg"
} | 001039 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "(A) Endoscopic view of the esophagogastric anastomosis demonstrating complete closure of the leakage after removal of the Hanarostent. Arrows indicate the area of the former leakage. (B) Gastrografin swallow.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1831780-2-1471-230X-7-10-3.jpg"
} | 001040 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "The whorl pattern in a breast cancer patient.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1831782-0-1471-2407-7-44-2.jpg"
} | 001041 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "The arch pattern in a control.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1831782-1-1471-2407-7-44-3.jpg"
} | 001042 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "The loop pattern in control.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1831782-2-1471-2407-7-44-1.jpg"
} | 001043 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Chromosomal location of bovine RTEL. Bovine RTEL gene is mapped to chromosome 13 by radiation hybrid mapping (RH mapping) and fluorescence in situ hybridization (FISH). The numbers indicated the PCR results of RH mapping, 1 and 0 represent positive and negative signals respectively. RTEL was mapped to bovine chromosome 13, placed 10.87 cR from the CHGB mark (LOD>3.0). The FISH and G-banding results shown in the bottom further confirmed the RH mapping result, specific hybridization signals (arrows) were observed on homologous chromosomes 13q2.2 comparing to standard GTG-banded cattle karyotype.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1831785-1-1471-2199-8-18-2.jpg"
} | 001044 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Over-expression of caveolin-1 induces apoptosis of GH3 cells. (A) GH3 cells were transfected with pcDNA4-Caveolin-1 for 48 hours then subjected to TUNEL assays. Cells transiently expressing exogenous caveolin-1 (indicated by arrowheads) showed shrunken morphologies (a and b) and nuclear fragmentation when stained with Hoechst 33342 dye (c) and were positively fluorescence-labeled by TUNEL assay (d). Cells directly treated with DNase I (e, f) or vehicle (g, h) were TUNEL positive (f) or negative (h), respectively. Nuclei stained with Hoechst 33342 dye are shown in c, e and g. (B) Caveolin-1 elicited apoptosis of GH3 cells. GH3 cells were transfected with pcDNA4-caveolin-1, pcDNA4-EGFP or vehicle (null treatment) and subjected to immunocytochemical staining 24 and 48 hours after transfection. Three hundred cells were randomly chosen and counted in each experiment (vehicle, caveolin-1 or EGFP) to determine the percentage with fragmented nuclei after Hoechst 33342 dye labeling. Apoptotic cells were measured by fluorescence labeling and data were expressed as mean ± standard deviation from n = 3 independent experiments (angular transformed for analysis, back-transformed for presentation). The standard deviations are too small to observe in the 48 hours data. **P < 0.01 and *P < 0.05 versus EGFP or vehicle experiment.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832175-2-1475-2867-7-1-3.jpg"
} | 001045 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Overexpression of caveolin-1 induces nuclear condensation in GH3 cells. GH3 cells were transfected with either pcDNA4-caveolin-1 (A, C and E) or pcDNA4-EGFP (B, D and F). Immunocytochemical staining was carried out 48 hours after transfection. Phalloidin conjugated-Texas-Red (A and B) and Hoechst 33342 (E and F) dyes were used to stain F-actin and nuclei respectively. Cells expressing caveolin-1 (arrowhead) were visualized by anti-rabbit IgG conjugated-FITC secondary antibody (C). Caveolin-1 overexpressing cells exhibit nuclear condensation (E), while normal nuclei (arrow) were detected in cells over-expressing EGFP (F). Scale bar = 20 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832175-3-1475-2867-7-1-2.jpg"
} | 001046 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Female embryo (left) and male embryo (right), both infected with S. poulsonii (16–18 h AEL). The top pictures, A and B, shows fluorescence with anti-SXL antibody in female and male respectively, and the bottom pictures, C and D, show the embryos structure under DAPI in female and male respectively. The female has developed normally and reached stage 16, the male has arrested before segmentation, and shows a characteristic amnioseral bulge.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832177-0-1741-7007-5-9-2.jpg"
} | 001047 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "TUNEL staining of Spiroplasma infected male embryo (A) and female embryo (B), both at stage 10, 5–7 h AEL. Red fluorescence indicates apoptotic nuclei; whilst the female embryo shows the characteristic pattern of apoptotic nuclei restricted to the cephalic furrow, apoptotic nuclei are observed throughout the male.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832177-1-1741-7007-5-9-3.jpg"
} | 001048 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Validation of adipose tissue quantification method against an anatomical reference standard from the Visible Human Project. The image on the left is an abdominal transaxial MR image allocated at the upper liver lobe of the Visible Human Male [15, 16]. The image on the right is the corresponding cryosection image obtained from the same subject. Quantified percent subcutaneous adipose tissue values for both images are reported below the respective image.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832180-0-1471-2342-7-3-1.jpg"
} | 001049 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "The RL generates EGFP+ cells that are not precursors of DCN neurons (E12.5–E13.5). A: lower power view of a future Cb hemisphere at E12.5 illustrating the pattern of EGFP expression in two seemingly related cell populations: tightly packed bipolar cells in the RL, and isolated cells with a unipolar shape and a leading process contacting the pial surface in the nascent EGL, which is characteristic of migrating GPs (arrows). B, C: higher power views of the E12.5 RL, illustrating the localisation of EGFP+ Pax6+ cells in the medial (B), and lateral (C), portion of the RL, and the presence of Pax6+ EGFP- cells in the nascent EGL (arrowheads). Nuclei of the cells in which EGFP/Pax6 co-expression is obvious are marked by colored dots, EGFP+ Pax6- cells by asterisks. The long branching processes emitted by the RL EGFP+ cell population are better visualized in C. D: at E13.5 and on coronal sections, the Olig2+ NTZ (1) and EGFP+ EGL (2) constitute clearly distinct populations.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832187-0-1471-213X-7-17-6.jpg"
} | 001050 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "S100B gene driven expression of EGFP in S100B+ cells of the ventricular and cortical transitory zones of the cerebellum at E17.5. A: confocal fluorescent image of a parasagittal section of the E17.5 S100B-EGFP cerebellar vermis. In addition to neural cells, the EGFP reporter is strongly expressed in the mesenchyme underlying the CPe. The staining patterns for S100B and EGFP are overlapping near the MHB (B), in the VZ (C), CTZ (D), and RL (E). The white dashed lines mark the ventricular and pial limits of the Cb. In this and the following figures, numbers above bars indicate the scale in microns.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832187-1-1471-213X-7-17-1.jpg"
} | 001051 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "EGFP+ Pax6+ granule precursors in the RL and EGLat E14.5. A: lower power view of the lateral portion of the future Cb hemisphere, illustrating the pattern of EGFP/Pax6 co expression in the RL and EGL at E14.5. B: higher power view of the EGL showing clusters of migrating Pax6+ EGFP+ neuron precursors with their intensely Pax6+ nuclei (upper panel) and EGFP+ cytoplasm (lower panel). C: higher power view of the RL illustrating the predominant population of EGFP+ Pax6+ cells (colored dots) and the presence of EGFP+ Pax6- cells (asterisks).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832187-2-1471-213X-7-17-7.jpg"
} | 001052 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "EGFP is not expressed in post-mitotic calbindin+ Purkinje progenitors (E13.5–E16.5). A: lower power view of the lateral portion (future hemisphere) of the E13.5 Cb plate illustrating the broad subcortical distribution of calbindin+ PCs. B: higher power view of the boxed area in (A), illustrating the contacts between post-mitotic calbindin+ EGFP-negative PC precursors (white dots) and EGFP+ radial glial processes. Arrowheads point to the non specific red fluorescence of small capillaries. C: at E16.5, the radial glia-derived EGFP+ cell population is greatly increased. D-F: no matter which region of the Cb primordium is examined, the EGFP+ and calbindin+ populations are clearly separate entities. Most EGFP+ cells are connected to the pial surface via their apical process, constituting the so-called secondary radial glial scaffold used by the EGL population of GPs during their postnatal phase of radial migration.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832187-3-1471-213X-7-17-4.jpg"
} | 001053 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "S100B and EGFP are co-expressed in the radial glial scaffold of the cerebellar plates (E14.5 and E16.5). A: lower power view of the lateral portion (future hemisphere) of the E14.5 cerebellum plate. B: higher power view of the boxed area in (A), illustrating localization of cell somata in the VZ and long radial processes traversing a CTZ filled with post-mitotic β3-tubulin+ neuron precursors (inset). C: zooming on the VZ area reveals a high level of S100B/EGFP colocalisation at the single cell level. D: As expected for radial glial cells, EGFP+ cells present in the VZ express BLBP. E: at E16.5, and in addition to radial glial cells and CPe cells, Sox9 expression is maintained in isolated cells emigrating from the VZ (arrowheads).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832187-4-1471-213X-7-17-3.jpg"
} | 001054 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "pattern of S100B gene expression in the cerebellum and inferior colliculus before midline fusion of the cerebellar plates (E13.5). A: lower power confocal image of the Cb primordium, illustrating the strong EGFP signal present near the MHB (red box) in a parasagittal section. B: zooming on the boxed area in A reveals the high level of S100B/EGFP colocalisation at the single cell level. C: near the MHB, and on coronal sections, EGFP tags a stretch of neuroepithelial cells approx. 300 μM in width, emitting thin processes towards the pial surface (arrowheads). The red dotted lines represent the approximate planes of sections D and F. The glial scaffold (boxed area) is entirely (D, E) or only partially visible (F), depending on how close to the midline is the plane of section. E: higher magnification of the boxed area in (D) illustrating the pattern of EGFP expression near the midline: both the S-shaped radial glial scaffold of the Cb, and the abutting IC neuroepithelium, are strongly labeled.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832187-5-1471-213X-7-17-2.jpg"
} | 001055 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "EGFP is not expressed in the cerebellar rhombiclip before E12.5. A lower power view of a future Cb hemisphere at E11.5 illustrates the absence of EGFP expression in the rhombic lip, contrasting with its presence in the neighbouring mesenchyme (arrowhead), posterior semicircular canal (SCC) of the otic vesicle, and glial cells of the trigeminal (V) and facial (VII) ganglions.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832187-6-1471-213X-7-17-5.jpg"
} | 001056 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Plaque analysis of 18-month-old APP and APP/Snca-/- animals. A. Sections were stained with 6E10 antibody or thioflavine S as indicated. 6E10 staining revealed the total plaque load while thioflavine S detected mature plaques only. The plaque density is much higher in mice lacking α-synuclein when compared to APP controls. Scale bar: 100 μm. B. Bar graph indicating the density of plaques per square area. The plaque density in the APP/Snca-/- animals exceeds that of the APP animals by 3–4 fold. N = 4, ***p < 0.001",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832188-1-1750-1326-2-6-3.jpg"
} | 001057 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Top, the hysterectomy specimen contained residual poorly demarcated tumor (left) and multiple leiomyomata (right). Bottom, sections from the uterine tumor showed residual mononucleated plump to spindle shaped tumor cells (left upper corner) and inflammatory cells, including foamy macrophages, osteoclast-type giant cells, and histiocytes (lower right). See the text for complete pathologic description.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832205-0-1471-2407-7-46-5.jpg"
} | 001058 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "CT scan at start of chemotherapy.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832205-1-1471-2407-7-46-2.jpg"
} | 001059 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Top, endometrial curetting showed aggregates of plump mononuclear cells with numerous large multinucleated osteoclast-type giant cells. Benign endometrial glands are seen at right center and right upper corner. Bottom, Fine needle aspirate of the lung showed sheets of mononuclear plump cells and numerous scattered osteoclast-type giant cells. See the text for complete pathologic description.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832205-4-1471-2407-7-46-1.jpg"
} | 001060 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "SW 1353 chondrosarcoma at day 28 after tumor implantation, hematoxylin-eosin stained cross section from representative tissue samples of the cranial window preparation. A, D: 4-fold magnification, scale bar 500 μm. B, C, E, F: 20-fold magnification, scale bar 100 μm. In Controls, the overview magnification shows a large tumor formation with high cellular density (A). Enlarged cutaway views (B, C) from the framed regions show high cellular density and destructive tumor growth with resorption of the surrounding bone (arrows, tips pointing to resorption lacunae). In SU6668, tumor size was markedly reduced (D). Enlarged cutaway views (E, F) from the framed regions show fibrous \"scar\" tissue with residual tumor cells and low cellular density and regenerative bone formation at sites of previous bone resorption (double arrows, distal tip pointing to former resorption front, proximal tip pointing to new mineralization front).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832206-0-1471-2407-7-49-2.jpg"
} | 001061 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "A: Functional vessel density, time course. Y-axis: functional vessel density (FVD in mm/mm2), x-axis: time in days after tumor implantation. SU6668 induced a regression of functional vessel density (FVD), while FVD in Controls increased between day 7 and 14 after tumor implantation, remaining constant thereafter. B: Tumor surface, time course. Y-axis: tumor surface (ATUM in mm2), x-axis: time in days after tumor implantation. In Controls, tumor surface continuously increased over the period of investigation. In contrast to this, SU6668 induced a growth arrest of chondrosarcomas beginning on day 14 after tumor implantation. A and B: Treatment started on day 7 after tumor implantation. Results are given as median with 25% quartiles and 75 % quartiles. Mann-Whitney rank sum test, #p < 0.05 versus Control, *p < 0.05 versus day 7 after tumor implantation. C and D: Immunohistochemistry for CD31 (PECAM-1) on day 28 after tumor implantation confirmed the results of the in vivo quantification of the functional vessel density with intravital microscopy. Untreated Controls showed uniformly distributed CD31 positive cells (brown) within the implanted tumors (C). In SU6668 treated tumors, CD31 positive cells were rare and only detectable in peripheral areas of the tumor residues (D). Scale bars represent 50 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1832206-1-1471-2407-7-49-1.jpg"
} | 001062 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "From left to right, examples of normal mitral annulus and calcified mitral annulus (mild = 1–2 mm, moderate = 2–5 mm and severe >5 mm calcified annulus).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838405-0-1476-7120-5-14-1.jpg"
} | 001063 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Magnetic resonance T1-weighted contrast-enhanced imaging; sagittal view.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838406-1-1471-2415-7-4-2.jpg"
} | 001064 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "The functional flowchart and software structural platform design of the Virtual Interactive Musculoskeletal System (VIMS) and database for biomechanical analyses.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838408-9-1749-799X-2-2-1.jpg"
} | 001065 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Analysis of transfected neurons in vivo and in vitro. (a) The eye of a 2 dpf embryo electroporated with pHuC:GAL4/pUAS:dnRyk-EGFP. Cells in multiple retinal layers are transfected in a distinct segment according to electrode positioning and injection site. Retinal ganglion cell axons are visible in the optic nerve (on). (b) A habenular (Ha) neuron contransfected with pHuC:GAL4/pUAS:dnEphB3-EGFP shows ectopic processes branching over the medial epithalamus, including the pineal organ (P). Extracellular exosome-like vesicles (arrowheads) are visible around the soma and processes. (c) Two habenular neurons (asterisks) expressing EGFP show the normal ventro-posterior projection into the fasciculus retroflexus (arrowheads). Commissural axons (arrow) are not derived from the habenula. (d) Bright field phase contrast and (e) fluorescence images of a 2 dpf forebrain explant from an embryo electroporated with pHuC:GAL4/pUAS:EGFP after 12 hours in culture. EGFP positive neurons and axons (arrowheads) can be tracked over time. Anterior is to the left in (a) (lateral), (b,c) (dorsal). Dashed lines indicate the midline. Scale bars = 50 μm. L, lens.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838412-0-1749-8104-2-6-3.jpg"
} | 001066 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Whole mount immunocytochemistry of electroporated brains. Isolated 4 dpf brains from embryos in which pHuC:GAL4/pUAS:EGFP were unilaterally electroporated into the right forebrain. Brains were stained with (a,d,g,j) anti-acetylated tubulin to label axons (red) and (b,e,h,k) anti-GFP to mark transfected cells (green); (c,f,i,l) merged images. Widespread expression of EGFP is seen in neuronal cell bodies of the right telencephalon and diencephalon (b,e). All major commissures contain labeled fibers and contralateral axonal projections can be seen in detail in left and ventral views (h,k). Anterior is to right in (d-f), to the left in all other panels. Scale bar = 100 μm. Ac, anterior commissure; Ha, habenula; hc, habenular commissure; Hy, hypothalamus; ot, optic tract; OT, optic tectum; pc, posterior commissure; poc, postoptic commissure; T, telencephalon.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838412-1-1749-8104-2-6-4.jpg"
} | 001067 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Results of electroporation at 2 dpf. (a) A 2 dpf embryo after electroporation at 24 hpf with 0.7 mg/ml each pHuC:GAL4/pUAS:EGFP. Axons of the developing habenular (arrowhead) and posterior (arrow) commissures are visible. (b) A 2 dpf embryo electroporated with 0.5 mg/ml each pHuC:GAL4/pUAS:EGFP/pUAS:mCherry. The mCherry channel (red) is less well resolved compared to EGFP (green) due to suboptimal excitation with a 543 nm laser line. Approximately 60% of cells express both transgenes at high levels (yellow). (c) Time series of commissural axons in the habenular commissure. Images were collected at room temperature, and growth cone migration is slower than normal. (d,e) Acridine orange staining two hours after electroporation shows higher levels of scattered cell death bilaterally in the brains of electroporated embryos (e) compared to unelectroporated siblings (d). Dorsal views, anterior to the left. Dashed lines indicate the midline. Time is hours:minutes. Scale bars = 50 μm. OT, optic tecum; P, pineal organ.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838412-2-1749-8104-2-6-2.jpg"
} | 001068 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Congenital MCMV infection in E18 fetal membranes. Pregnant SCID mice were injected with 103 PFU of MCMV at E4. A: H&E staining of an E18 SCID mouse placenta with extraembryonic membranes. ST, spongiotrophoblastic zone; LT, labyrinthine zone; visceral yolk sac in box. B: Anti-MCMV immunostaining (green; arrow) for viral antigens in the mesodermal layer of the visceral yolk sac boxed in (A). C: In situ hybridization (purple; arrow) for MCMV RNA in the mesodermal layer of the visceral yolk sac boxed in (A). D: Anti-MCMV immunostaining (green) in endothelial cells (anti-CD31+: red) in the walls of blood vessels (arrows) within the visceral yolk sac of an E18 embryo. E: Anti-MCMV immunostaining (green, arrows) within macrophages (anti-F4/80: red) in the visceral yolk sac mesoderm of an E18 embryo. A,D&E: Bisbenzimide nuclear stain (blue). A: Bar = 1 mm; B&C: Bars = 100 μm, D&E: Bars = 20 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838414-2-1743-422X-4-26-2.jpg"
} | 001069 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Flow chart showing a summary of the study including the preliminary evaluations, the non-human images, and the human in-vivo imaging.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838416-0-1471-2342-7-4-7.jpg"
} | 001070 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Localisation of the gold acupuncture needle inserted into the Shen mai point on the right ankle. A small image attenuation defect can be observed at the site where the needle was inserted (arrow). The tip of the needle was located close to the tendons of the peroneal muscles at the fibular malleolus. It should be noted, that the fibulo-maleolar ligament has not been reached. MRI acquisition data: TR = 500, TE = 11, flip = 150, TH = 2, TF = 3, FOV = 170, MA = 384.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838416-1-1471-2342-7-4-6.jpg"
} | 001071 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Preliminary imaging procedure using the gold needle inserted into an onion. Note the image attenuation area around the needle. In these experiments the length of the inserted portion corresponded to the length of the image attenuation effect. The width of the defect was much larger than the width of the gold needle.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838416-3-1471-2342-7-4-2.jpg"
} | 001072 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "In-vivo localisation of the gold acupuncture needle inserted into the Dai mai point as seen in a saggital slice reconstruction. The white arrow simulates the direction of needle insertion. Image reconstruction was done with the J-Vision software of the TIANI workstation. MRI acquisition data: TR = 721, TE = 19, flip = 150, TH = 3, TF = 3, FOV = 370, MA = 320.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838416-5-1471-2342-7-4-4.jpg"
} | 001073 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Preliminary imaging procedure using the gold needle inserted into a banana. Note the image attenuation area around the needle similar to that shown in figure 2. In these experiments the length of the inserted portion corresponded to the length of the image attenuation effect. The width of the defect was much larger than the width of the gold needle.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838416-6-1471-2342-7-4-3.jpg"
} | 001074 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Immunohistochemical staining revealing the presence of Sema-4D in the mouse ovary at all stages: (A) un-stimulated (B) after PMSG administration, (C) 6 hours after hCG administration, and (D) 24 hours after hCG administration. Sema-4D was identified as red-brown membrane staining in ovarian sections counterstained with hematoxylin; magnification ×400. Bar graph describing the relative percentage of Sema-4D expression, representing, mean ± SEM from three independent experiments.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838422-0-1477-7827-5-12-1.jpg"
} | 001075 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "HE stained section of a donor block. The section is used to identify areas of interest in the donor block for extraction of cores to place in the array block (identified by a pathologist with red or black ink). The positions where cores have been extracted are marked with black circles. Moving the mouse over a core position displays detailed information about the related array block, the position of the core on the array block and the index of the core on the donor block.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838435-0-1471-2105-8-81-1.jpg"
} | 001076 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Microtubule localization at 37°C conditions. Microtubules are distributed throughout wild type cells. Microtubules are found in localized areas of KN99α rom2 hyperelongated cells. The distribution of cellular material between mother and daughter cell is well defined for wild type cells but is enlarged over a greater area in hyperelongated cells. Arrowheads indicate the location of microtubule patches. Microtubules are distributed throughout mother and daughter cells in KN99α. However, microtubules are localized to the neck region and periphery of the hyperelongated KN99α rom2 cells. Arrows indicate microtubule extensions between mother and daughter cells.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838519-1-ponep0000368pg005.jpg"
} | 001077 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "C. neoformans actin expression at 37°C in KN99α and KN99α rom2. F-actin is identified with rhodamine-phalloidin. Actin is distributed throughout the wild type cell. White arrows indicate actin localization at the cell periphery and at the bud tips of KN99α rom2 hyperelongated cells. The black arrow indicates the region of the cell that is defective for cytokinesis indicated by a lack of cell wall formation between the cell complexes.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838519-2-ponep0000368pg004.jpg"
} | 001078 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Individual cell localization of actin and microtubules. Actin staining with rhodamine-phalloidin of both KN99α and KN99α rom2 cells at 30°C and 37°C. Microtubules were identified using a TAT1 antibody and staining with goat anti mouse secondary antibody as described in the materials and methods.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838519-3-ponep0000368pg003.jpg"
} | 001079 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Reversal flow during atrial systole in ductus venosus.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838895-0-1476-7120-5-15-5.jpg"
} | 001080 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Reversal end diastolic flow in umbilical artery.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838895-3-1476-7120-5-15-4.jpg"
} | 001081 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Highlighting of ductus venosus.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838895-4-1476-7120-5-15-1.jpg"
} | 001082 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "A histology slide of benign breast tissue stained with H&E and an image spot of size comparable to the tissue samples used in tissue microarrays. The image block is 0.66 × 1.03 mm2 while the full tissue section is 2.04 × 2.89 cm2.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838905-10-1471-2342-7-2-2.jpg"
} | 001083 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Randomly selected image blocks from the ground truth dataset. The images on the left indicate normal/benign breast tissue, while the images on the right represent examples of Invasive Ductal Carcinoma.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838905-11-1471-2342-7-2-5.jpg"
} | 001084 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Sample image blocks of normal-specific, cancer-specific, and non-specific histological appearance clusters as identified simultaneously based on texture parameters obtained from grayscale and color tissue segmentation algorithms.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838905-7-1471-2342-7-2-12.jpg"
} | 001085 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Histology image segmentation into chromatin-rich, stromal, and unstained regions using image intensity. A grayscale value is computed for each pixel as the average of red, green, and blue color channels, and a 3 cluster k-means algorithm is used to determine the intensity thresholds between the respective clusters. The lowest intensity range is associated with the cell populated regions, while the highest intensity range determines the adipose tissue and the background. The middle intensity range corresponds to the stroma.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838905-9-1471-2342-7-2-3.jpg"
} | 001086 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Expression pattern of the Cs-pb gene. (A) Limb bud stage, proboscipedia (pb) is expressed in the pedipalpal segment (Pp) and walking leg segments (L1-L4). The expression is most prominent in the appendages itself, but there is also some weaker expression in the ventral ectoderm (arrows). There is no expression in the cheliceral segment (Ch) or in the opisthosomal segments. (B) Inversion stage, pb is expressed in the appendages of the Pp and L1-L4 segments and in spots (arrowheads) in the ectoderm ventral to the appendages. Also at these older stages the cheliceral and opisthosomal segments are free of expression. Both embryos: ventral view.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838909-0-1742-9994-4-10-2.jpg"
} | 001087 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Expression pattern of the Cs-Ubx-1 and Cs-Ubx-2 genes. The anterior expression border of both Ubx genes is in the second opisthosomal segment (O2). The one of Cs-Ubx-1 (A) is at the anterior edge of O2, while the one of Cs-Ubx-2 is at posterior portion of O2 and corresponds to the parasegment boundary [15]. The opisthosomal limb primordia that will form the respiratory organs and spinnerets are visible on O2-O5. Abbreviations: L4: walking leg 4, O1-O6: opisthosomal segment 1–6.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838909-1-1742-9994-4-10-5.jpg"
} | 001088 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Expression pattern of the Cs-Scr-1 and Cs-Scr-2 genes. Expression of the Cs-Scr-1 gene (A-C) and the Cs-Scr-2 gene (D-F). At the limb bud stage Scr-1 is more or less homogenously expressed in L2, L3 and L4 (arrow in A). At later stages there is expression in rings in the legs of L3 and L4 (B) and later also weak expression in the legs of L2 (C). Scr-2 expression starts as small spots in the ventral ectoderm of L2, L3 and L4 (arrowheads in D) that persist during further development (E,F). Later there is also Scr-2 expression in the legs of L3 and L4, but in contrast to Scr1 we never observed expression in the legs of L2 (F). Ch: cheliceres, Pp: pedipalps, L1-L4: walking leg 1–4.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838909-2-1742-9994-4-10-4.jpg"
} | 001089 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Expression pattern of the Cs-Dfd-1 and Cs-Dfd-2 genes. The Cs-Dfd-1 gene (A-C) and the Cs-Dfd-2 gene (D-F) are expressed in the four segments that bear the walking legs (L1-L4). Expression is seen in the appendages as well as in the ventral ectoderm. The ventral ectoderm expression of Cs-Dfd-1 is stronger than the one of Cs-Dfd-2, especially at the older stages (B and C compared with E and F). The expression patterns in the legs are different for the two genes (most obvious in C an F), while in addition, Cs-Dfd-2 expression in L3 and L4 is weaker compared to the expression in L1 and L2. The level of Cs-Dfd-1 expression is similar for all four legs. A and D: ventral view of limb bud stage, B and E: ventral view of limb stage before inversion, C and F: lateral view of inversion stage. There is never ever expression of any of the two spider Dfd genes in the cheliceral (Ch), pedipalpal (Pp), or opisthosomal segments.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838909-3-1742-9994-4-10-3.jpg"
} | 001090 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Tissue Type Specific Expression of GFP Reporter Gene in Zebrafish Embryos. Examples of GFP expression induced by CNEs 1, 9, 10, and 11 are shown in fixed tissues after wholemount anti-GFP immunostaining (bright field views A and F) or in live embryos by combined bright field and GFP fluorescence microscopy analyses (B, C, D, E, G and H). Arrowheads indicate GFP expressing cells. Embryos C and D are ∼26–33 hpf, while embryos A, B, E, F, G, and H are 48–54 hpf. Lateral views, anterior to the left and dorsal to the top except for F where the dorsal view is shown. GFP positive cells were found in the following: (A) CNE1, heart chamber (B) CNE1, hindbrain neurons (C) CNE9, notochord (D) CNE9, spinal cord neuron (E) CNE10, lower jaw primordia and pericardial regions (F) CNE10, lens epithelial cell layer (G) CNE11, pectoral fin (H) CNE11, muscle. (e) Eye; (f) fin; (h) heart; (hb) hindbrain; (I) lens; (nc) notochord; (ov) otic vesicle; (r) retina; (s) spinal cord; (y) yolk.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838922-0-ponep0000366pg004.jpg"
} | 001091 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Representative in situ zymography results demonstrating\ngelatinase activity by MMPs in the dentate gyrus in the presence\nof (a) PBS (control condition) upper panels or (b) FN-439\n(14.4 mM) lower panels. The equivalent blue fluorescence of\ncell nuclei suggests no cellular toxicity. MMP-2 and MMP-9\nactivity, visualized as green fluorescence, was significantly\ninhibited by FN-439 as evidenced by reductions in green\nfluorescence.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1838960-2-NP2007-73813p005.jpg"
} | 001092 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Exposure of mixed glial cultures to low GM-CSF results in the ramification of resting microglia with a DC-like appearance. Primary microglia expanded either with or without GM-CSF were seeded onto 35-mm dishes at 2 × 106 cells per dish and incubated overnight in 6-well plates. The following day, cells were either unstimulated or treated with heat-inactivated S. aureus (107 cfu/well) for 24 h, whereupon bright field phase-contrast images were collected (40×). The results pictured are representative of two independent experiments.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1839084-5-1742-2094-4-10-2.jpg"
} | 001093 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "A trans-scapular roentgenogram shows the pedunculated shape of an osteochondorma at the inferior aspect of the anterior scapula.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1839090-0-1477-7819-5-37-1.jpg"
} | 001094 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Endoscopic image shows that the tumor was removed by use of a grasper.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1839090-2-1477-7819-5-37-3.jpg"
} | 001095 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Postoperatively, CT reveals the complete resection the tumor.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1839090-3-1477-7819-5-37-4.jpg"
} | 001096 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Histology reveals a regular cartilage cap without malignant transformation. (Straight line: 100 μm).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1839090-4-1477-7819-5-37-5.jpg"
} | 001097 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "CT image shows an osteochondroma on the anterior and inferior surface of the right scapula.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1839090-5-1477-7819-5-37-2.jpg"
} | 001098 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
|
{
"caption": "Computed tomography after chemotherapy A – regression of focal changes in liver is visible B – regression of metastases in lungs is visible.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_0_108-PMC1839091-0-1477-7819-5-36-2.jpg"
} | 001099 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00000.tar |
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