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<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-266 Date of Submission: 2024-10-02 This report was submitted by a Other Healthcare Professional from Jackson, Harrison and Thomas Medical Center concerning patient ANON-PX-9140. The subject is a 53-year-old male with a significant medical history including seasonal allergies, coronary artery disease, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Intravenous route at a dosage of 79mg, initiated on 2024-08-11 for Gastroesophageal reflux disease and discontinued on 2024-09-28; Sertraline (SSRI) administered via the Intravenous route at a dosage of 498mg, initiated on 2024-08-11 for Major depressive disorder and discontinued on 2024-09-28. On approximately 2024-09-25, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Angioedema, Maculopapular Rash, Vomiting. The Anaphylaxis was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Angioedema was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Maculopapular Rash was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Vomiting was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. </data>	report_id: ADR-2024-266 report_date: '2024-10-02' patient_details: patient_id: ANON-PX-9140 gender: Male relevant_history: - seasonal allergies - coronary artery disease - osteoarthritis age_at_reaction: 53 suspected_drugs: - drug_name: Omeprazole dosage: 79mg route_of_administration: Intravenous start_date: '2024-08-11' indication_for_use: Gastroesophageal reflux disease drug_class: Proton-pump inhibitor end_date: '2024-09-28' - drug_name: Sertraline dosage: 498mg route_of_administration: Intravenous start_date: '2024-08-11' indication_for_use: Major depressive disorder drug_class: SSRI end_date: '2024-09-28' adverse_reactions: - symptom_name: Anaphylaxis onset_date: '2024-09-25' severity: Mild outcome: Fatal intervention_required: false - symptom_name: Angioedema onset_date: '2024-09-25' severity: Mild outcome: Unknown intervention_required: false - symptom_name: Maculopapular Rash onset_date: '2024-09-25' severity: Mild outcome: Not Recovered intervention_required: false - symptom_name: Vomiting onset_date: '2024-09-25' severity: Mild outcome: Recovering intervention_required: false causality_assessment: assessment_conclusion: Possible dechallenge_rechallenge: Not applicable naranjo_score: 4 reporting_facility: Jackson, Harrison and Thomas Medical Center reporter_type: Other Healthcare Professional
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-630 Date of Submission: 2024-10-09 This report was submitted by a Pharmacist from Tanner-Anderson Medical Center concerning patient ANON-PX-5552. The subject is a 62-year-old male with a significant medical history including migraines, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Metformin administered via the Oral route at a dosage of 373mg, initiated on 2024-09-27 for Type 2 diabetes and discontinued on 2024-10-05; Warfarin (Anticoagulant) administered via the Topical route at a dosage of 180mg, initiated on 2024-09-27 for Thromboembolism prevention and discontinued on 2024-10-05. On approximately 2024-10-03, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Angioedema, Stevens-Johnson syndrome, Pruritus. The Somnolence was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Angioedema was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Stevens-Johnson syndrome was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Pruritus was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Wonder catch season everyone. Town answer firm institution society summer. Stock foot debate Mrs moment part look.</data>	report_id: ADR-2024-630 report_date: '2024-10-09' patient_details: patient_id: ANON-PX-5552 gender: Male relevant_history: - migraines - type 2 diabetes age_at_reaction: 62 suspected_drugs: - drug_name: Metformin dosage: 373mg route_of_administration: Oral start_date: '2024-09-27' indication_for_use: Type 2 diabetes end_date: '2024-10-05' - drug_name: Warfarin dosage: 180mg route_of_administration: Topical start_date: '2024-09-27' indication_for_use: Thromboembolism prevention drug_class: Anticoagulant end_date: '2024-10-05' adverse_reactions: - symptom_name: Somnolence onset_date: '2024-10-03' severity: Moderate outcome: Recovered intervention_required: false - symptom_name: Angioedema onset_date: '2024-10-03' severity: Life-threatening outcome: Recovering intervention_required: true - symptom_name: Stevens-Johnson syndrome onset_date: '2024-10-03' severity: Mild outcome: Not Recovered intervention_required: false - symptom_name: Pruritus onset_date: '2024-10-03' severity: Moderate outcome: Fatal intervention_required: false causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Negative dechallenge reporting_facility: Tanner-Anderson Medical Center reporter_type: Pharmacist notes: Wonder catch season everyone. Town answer firm institution society summer. Stock foot debate Mrs moment part look.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-503 Date of Submission: 2024-12-04 This report was submitted by a Physician from Garcia, Reynolds and Bradford Medical Center concerning patient ANON-PX-4262. The subject is an adult other with a significant medical history including seasonal allergies, asthma, migraines, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Metformin (Biguanide) administered via the Intravenous route at a dosage of 463mg, initiated on 2024-11-24 for Type 2 diabetes and discontinued on 2024-12-02. On approximately 2024-11-29, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Pruritus, Vomiting, Stevens-Johnson syndrome. The Angioedema was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Pruritus was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Vomiting was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. </data>	report_id: ADR-2024-503 report_date: '2024-12-04' patient_details: patient_id: ANON-PX-4262 gender: Other relevant_history: - seasonal allergies - asthma - migraines - anxiety suspected_drugs: - drug_name: Metformin dosage: 463mg route_of_administration: Intravenous start_date: '2024-11-24' indication_for_use: Type 2 diabetes drug_class: Biguanide end_date: '2024-12-02' adverse_reactions: - symptom_name: Angioedema onset_date: '2024-11-29' severity: Mild outcome: Recovering intervention_required: true - symptom_name: Pruritus onset_date: '2024-11-29' severity: Severe outcome: Not Recovered intervention_required: false - symptom_name: Vomiting onset_date: '2024-11-29' severity: Moderate outcome: Fatal intervention_required: false - symptom_name: Stevens-Johnson syndrome onset_date: '2024-11-29' severity: Life-threatening outcome: Recovered intervention_required: false causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Not applicable reporting_facility: Garcia, Reynolds and Bradford Medical Center reporter_type: Physician
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-611 Date of Submission: 2024-12-27 This report was submitted by a Pharmacist from Brown Ltd Medical Center concerning patient ANON-PX-5603. The subject is a 19-year-old female with a significant medical history including chronic kidney disease, atrial fibrillation, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Sertraline (SSRI) administered via the Topical route at a dosage of 80mg, initiated on 2024-11-10 for Major depressive disorder and discontinued on 2024-12-26. On approximately 2024-12-06, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Angioedema. The Vomiting was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Angioedema was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed experience and advised might. The current patient status regarding this symptom is 'Fatal'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Senior station area artist where. East no production million although myself.</data>	report_id: ADR-2024-611 report_date: '2024-12-27' patient_details: patient_id: ANON-PX-5603 gender: Female relevant_history: - chronic kidney disease - atrial fibrillation - type 2 diabetes age_at_reaction: 19 suspected_drugs: - drug_name: Sertraline dosage: 80mg route_of_administration: Topical start_date: '2024-11-10' indication_for_use: Major depressive disorder drug_class: SSRI end_date: '2024-12-26' adverse_reactions: - symptom_name: Vomiting onset_date: '2024-12-06' severity: Severe outcome: Fatal intervention_required: false - symptom_name: Angioedema onset_date: '2024-12-06' severity: Mild outcome: Fatal intervention_required: true intervention_details: Prescribed experience and advised might. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Rechallenge not performed reporting_facility: Brown Ltd Medical Center reporter_type: Pharmacist notes: Senior station area artist where. East no production million although myself.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-263 Date of Submission: 2024-10-29 This report was submitted by a Pharmacist from Hill Ltd Medical Center concerning patient ANON-PX-2205. The subject is a 68-year-old male with a significant medical history including chronic kidney disease, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Metformin (Biguanide) administered via the Intramuscular route at a dosage of 393mg, initiated on 2024-08-07 for Type 2 diabetes and discontinued on 2024-10-22; Amoxicillin (Penicillin antibiotic) administered via the Subcutaneous route at a dosage of 240mg, initiated on 2024-08-07 for Bacterial infection and discontinued on 2024-10-22. On approximately 2024-08-09, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Headache, Somnolence, Pruritus, Diarrhea. The Stevens-Johnson syndrome was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Headache was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed strong and advised people. The current patient status regarding this symptom is 'Recovered'. The Somnolence was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed doctor and advised get. The current patient status regarding this symptom is 'Recovering'. The Pruritus was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Diarrhea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 8 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Thing close plan. Ball take protect why need visit. Science participant fill Democrat.</data>	report_id: ADR-2024-263 report_date: '2024-10-29' patient_details: patient_id: ANON-PX-2205 gender: Male relevant_history: - chronic kidney disease - atrial fibrillation age_at_reaction: 68 suspected_drugs: - drug_name: Metformin dosage: 393mg route_of_administration: Intramuscular start_date: '2024-08-07' indication_for_use: Type 2 diabetes drug_class: Biguanide end_date: '2024-10-22' - drug_name: Amoxicillin dosage: 240mg route_of_administration: Subcutaneous start_date: '2024-08-07' indication_for_use: Bacterial infection drug_class: Penicillin antibiotic end_date: '2024-10-22' adverse_reactions: - symptom_name: Stevens-Johnson syndrome onset_date: '2024-08-09' severity: Mild outcome: Recovering intervention_required: false - symptom_name: Headache onset_date: '2024-08-09' severity: Life-threatening outcome: Recovered intervention_required: true intervention_details: Prescribed strong and advised people. - symptom_name: Somnolence onset_date: '2024-08-09' severity: Life-threatening outcome: Recovering intervention_required: true intervention_details: Prescribed doctor and advised get. - symptom_name: Pruritus onset_date: '2024-08-09' severity: Mild outcome: Unknown intervention_required: true - symptom_name: Diarrhea onset_date: '2024-08-09' severity: Mild outcome: Recovered intervention_required: false causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive rechallenge naranjo_score: 8 reporting_facility: Hill Ltd Medical Center reporter_type: Pharmacist notes: Thing close plan. Ball take protect why need visit. Science participant fill Democrat.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-969 Date of Submission: 2025-05-04 This report was submitted by a Patient from Tran LLC Medical Center concerning patient ANON-PX-7997. The subject is a 27-year-old other with a significant medical history including osteoarthritis, asthma, migraines, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Subcutaneous route at a dosage of 28mg, initiated on 2025-03-07 for Hypothyroidism and discontinued on 2025-04-27; Gabapentin (Anticonvulsant) administered via the Subcutaneous route at a dosage of 297mg, initiated on 2025-03-07 for Neuropathic pain and discontinued on 2025-04-27. On approximately 2025-03-20, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Dizziness, Anaphylaxis, Somnolence, Pruritus. The Angioedema was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed per and advised same. The current patient status regarding this symptom is 'Recovering'. The Dizziness was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Anaphylaxis was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Somnolence was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed continue and advised trip. The current patient status regarding this symptom is 'Fatal'. The Pruritus was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Never yeah really say deal as alone. Third society sea system your might. Assume daughter perform both care.</data>	report_id: ADR-2025-969 report_date: '2025-05-04' patient_details: patient_id: ANON-PX-7997 gender: Other relevant_history: - osteoarthritis - asthma - migraines - type 2 diabetes age_at_reaction: 27 suspected_drugs: - drug_name: Levothyroxine dosage: 28mg route_of_administration: Subcutaneous start_date: '2025-03-07' indication_for_use: Hypothyroidism drug_class: Thyroid hormone end_date: '2025-04-27' - drug_name: Gabapentin dosage: 297mg route_of_administration: Subcutaneous start_date: '2025-03-07' indication_for_use: Neuropathic pain drug_class: Anticonvulsant end_date: '2025-04-27' adverse_reactions: - symptom_name: Angioedema onset_date: '2025-03-20' severity: Severe outcome: Recovering intervention_required: true intervention_details: Prescribed per and advised same. - symptom_name: Dizziness onset_date: '2025-03-20' severity: Mild outcome: Not Recovered intervention_required: false - symptom_name: Anaphylaxis onset_date: '2025-03-20' severity: Life-threatening outcome: Recovered intervention_required: false - symptom_name: Somnolence onset_date: '2025-03-20' severity: Mild outcome: Fatal intervention_required: true intervention_details: Prescribed continue and advised trip. - symptom_name: Pruritus onset_date: '2025-03-20' severity: Severe outcome: Fatal intervention_required: false causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive rechallenge reporting_facility: Tran LLC Medical Center reporter_type: Patient notes: Never yeah really say deal as alone. Third society sea system your might. Assume daughter perform both care.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-329 Date of Submission: 2025-08-09 This report was submitted by a Nurse from Rose PLC Medical Center concerning patient ANON-PX-1889. The subject is a 69-year-old male with a significant medical history including osteoarthritis, type 2 diabetes, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Intramuscular route at a dosage of 276mg, initiated on 2025-05-23 for Hypothyroidism with the course ongoing; Sertraline (SSRI) administered via the Topical route at a dosage of 274mg, initiated on 2025-05-23 for Major depressive disorder with the course ongoing. On approximately 2025-07-06, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Headache, Diarrhea, Dizziness, Angioedema, Nausea. The Headache was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Dizziness was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Angioedema was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Nausea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Could low indicate language just. Network some know according hour action. Despite relationship money follow group purpose.</data>	report_id: ADR-2025-329 report_date: '2025-08-09' patient_details: patient_id: ANON-PX-1889 gender: Male relevant_history: - osteoarthritis - type 2 diabetes - hypertension age_at_reaction: 69 suspected_drugs: - drug_name: Levothyroxine dosage: 276mg route_of_administration: Intramuscular start_date: '2025-05-23' indication_for_use: Hypothyroidism drug_class: Thyroid hormone - drug_name: Sertraline dosage: 274mg route_of_administration: Topical start_date: '2025-05-23' indication_for_use: Major depressive disorder drug_class: SSRI adverse_reactions: - symptom_name: Headache onset_date: '2025-07-06' severity: Mild outcome: Recovering intervention_required: false - symptom_name: Diarrhea onset_date: '2025-07-06' severity: Moderate outcome: Recovering intervention_required: false - symptom_name: Dizziness onset_date: '2025-07-06' severity: Moderate outcome: Not Recovered intervention_required: true - symptom_name: Angioedema onset_date: '2025-07-06' severity: Moderate outcome: Fatal intervention_required: true - symptom_name: Nausea onset_date: '2025-07-06' severity: Life-threatening outcome: Recovering intervention_required: false causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Negative dechallenge naranjo_score: 7 reporting_facility: Rose PLC Medical Center reporter_type: Nurse notes: Could low indicate language just. Network some know according hour action. Despite relationship money follow group purpose.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-500 Date of Submission: 2024-08-17 This report was submitted by a Other Healthcare Professional from Marshall-Bernard Medical Center concerning patient ANON-PX-2485. The subject is a 59-year-old male with a significant medical history including type 2 diabetes, anxiety, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Ibuprofen administered via the Topical route at a dosage of 372mg, initiated on 2024-07-29 for Pain and inflammation and discontinued on 2024-08-15. On approximately 2024-08-12, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Somnolence, Vomiting, Pruritus. The Angioedema was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Somnolence was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Vomiting was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed later and advised force. The current patient status regarding this symptom is 'Recovered'. The Pruritus was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed another and advised sit. The current patient status regarding this symptom is 'Unknown'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 6 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Ever student travel thing crime because word pretty. Long green ten. Size investment across agree friend almost.</data>	report_id: ADR-2024-500 report_date: '2024-08-17' patient_details: patient_id: ANON-PX-2485 gender: Male relevant_history: - type 2 diabetes - anxiety - chronic kidney disease age_at_reaction: 59 suspected_drugs: - drug_name: Ibuprofen dosage: 372mg route_of_administration: Topical start_date: '2024-07-29' indication_for_use: Pain and inflammation end_date: '2024-08-15' adverse_reactions: - symptom_name: Angioedema onset_date: '2024-08-12' severity: Severe outcome: Fatal intervention_required: false - symptom_name: Somnolence onset_date: '2024-08-12' severity: Life-threatening outcome: Fatal intervention_required: false - symptom_name: Vomiting onset_date: '2024-08-12' severity: Life-threatening outcome: Recovered intervention_required: true intervention_details: Prescribed later and advised force. - symptom_name: Pruritus onset_date: '2024-08-12' severity: Moderate outcome: Unknown intervention_required: true intervention_details: Prescribed another and advised sit. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive rechallenge naranjo_score: 6 reporting_facility: Marshall-Bernard Medical Center reporter_type: Other Healthcare Professional notes: Ever student travel thing crime because word pretty. Long green ten. Size investment across agree friend almost.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-863 Date of Submission: 2025-02-12 This report was submitted by a Patient from Smith Ltd Medical Center concerning patient ANON-PX-6231. The subject is an adult male with a significant medical history including migraines, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Subcutaneous route at a dosage of 248mg, initiated on 2024-11-16 for Hypothyroidism and discontinued on 2025-02-06. On approximately 2025-01-15, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Headache, Hepatotoxicity, Angioedema. The Maculopapular Rash was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed radio and advised level. The current patient status regarding this symptom is 'Not Recovered'. The Hepatotoxicity was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed send and advised anything. The current patient status regarding this symptom is 'Not Recovered'. The Angioedema was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. </data>	report_id: ADR-2025-863 report_date: '2025-02-12' patient_details: patient_id: ANON-PX-6231 gender: Male relevant_history: - migraines - osteoarthritis suspected_drugs: - drug_name: Levothyroxine dosage: 248mg route_of_administration: Subcutaneous start_date: '2024-11-16' indication_for_use: Hypothyroidism drug_class: Thyroid hormone end_date: '2025-02-06' adverse_reactions: - symptom_name: Maculopapular Rash onset_date: '2025-01-15' severity: Mild outcome: Recovered intervention_required: true - symptom_name: Headache onset_date: '2025-01-15' severity: Moderate outcome: Not Recovered intervention_required: true intervention_details: Prescribed radio and advised level. - symptom_name: Hepatotoxicity onset_date: '2025-01-15' severity: Severe outcome: Not Recovered intervention_required: true intervention_details: Prescribed send and advised anything. - symptom_name: Angioedema onset_date: '2025-01-15' severity: Mild outcome: Unknown intervention_required: false causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Negative dechallenge reporting_facility: Smith Ltd Medical Center reporter_type: Patient
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-367 Date of Submission: 2024-11-18 This report was submitted by a Physician from Gibbs, Bell and Watkins Medical Center concerning patient ANON-PX-5463. The subject is an adult male with a significant medical history including chronic kidney disease, migraines, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Topical route at a dosage of 472mg, initiated on 2024-09-10 for Hypertension with the course ongoing; Atorvastatin (Statin) administered via the Topical route at a dosage of 447mg, initiated on 2024-09-10 for Hypercholesterolemia with the course ongoing. On approximately 2024-09-28, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Nausea, Angioedema, Dizziness, Diarrhea. The Pruritus was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Nausea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed away and advised future. The current patient status regarding this symptom is 'Recovering'. The Dizziness was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 2 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Tax prevent agree PM human song budget. Stay quickly raise sometimes. Traditional recognize door art son late south open.</data>	report_id: ADR-2024-367 report_date: '2024-11-18' patient_details: patient_id: ANON-PX-5463 gender: Male relevant_history: - chronic kidney disease - migraines - atrial fibrillation suspected_drugs: - drug_name: Lisinopril dosage: 472mg route_of_administration: Topical start_date: '2024-09-10' indication_for_use: Hypertension drug_class: ACE inhibitor - drug_name: Atorvastatin dosage: 447mg route_of_administration: Topical start_date: '2024-09-10' indication_for_use: Hypercholesterolemia drug_class: Statin adverse_reactions: - symptom_name: Pruritus onset_date: '2024-09-28' severity: Mild outcome: Recovering intervention_required: false - symptom_name: Nausea onset_date: '2024-09-28' severity: Life-threatening outcome: Unknown intervention_required: false - symptom_name: Angioedema onset_date: '2024-09-28' severity: Moderate outcome: Recovering intervention_required: true intervention_details: Prescribed away and advised future. - symptom_name: Dizziness onset_date: '2024-09-28' severity: Moderate outcome: Recovering intervention_required: false - symptom_name: Diarrhea onset_date: '2024-09-28' severity: Severe outcome: Recovered intervention_required: true causality_assessment: assessment_conclusion: Possible dechallenge_rechallenge: Not applicable naranjo_score: 2 reporting_facility: Gibbs, Bell and Watkins Medical Center reporter_type: Physician notes: Tax prevent agree PM human song budget. Stay quickly raise sometimes. Traditional recognize door art son late south open.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-937 Date of Submission: 2025-07-28 This report was submitted by a Pharmacist from Sellers, George and Young Medical Center concerning patient ANON-PX-1313. The subject is an adult male with a significant medical history including coronary artery disease, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Metformin (Biguanide) administered via the Intramuscular route at a dosage of 125mg, initiated on 2025-07-01 for Type 2 diabetes with the course ongoing. On approximately 2025-07-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Maculopapular Rash. The Stevens-Johnson syndrome was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Maculopapular Rash was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. </data>	report_id: ADR-2025-937 report_date: '2025-07-28' patient_details: patient_id: ANON-PX-1313 gender: Male relevant_history: - coronary artery disease - type 2 diabetes suspected_drugs: - drug_name: Metformin dosage: 125mg route_of_administration: Intramuscular start_date: '2025-07-01' indication_for_use: Type 2 diabetes drug_class: Biguanide adverse_reactions: - symptom_name: Stevens-Johnson syndrome onset_date: '2025-07-18' severity: Life-threatening outcome: Unknown intervention_required: false - symptom_name: Maculopapular Rash onset_date: '2025-07-18' severity: Severe outcome: Not Recovered intervention_required: false causality_assessment: assessment_conclusion: Highly Probable dechallenge_rechallenge: Not applicable naranjo_score: 10 reporting_facility: Sellers, George and Young Medical Center reporter_type: Pharmacist
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-957 Date of Submission: 2025-07-25 This report was submitted by a Nurse from Garrett-Davis Medical Center concerning patient ANON-PX-3683. The subject is a 18-year-old other with a significant medical history including chronic kidney disease, hypertension, migraines, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Ibuprofen administered via the Topical route at a dosage of 359mg, initiated on 2025-06-05 for Pain and inflammation with the course ongoing; Metformin administered via the Subcutaneous route at a dosage of 344mg, initiated on 2025-06-05 for Type 2 diabetes with the course ongoing. On approximately 2025-06-07, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Dizziness, Diarrhea, Pruritus. The Angioedema was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Dizziness was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed road and advised toward. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Pruritus was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 1 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Imagine memory hair huge itself side heart. Number father war fish. Total could tough in institution everyone listen them.</data>	report_id: ADR-2025-957 report_date: '2025-07-25' patient_details: patient_id: ANON-PX-3683 gender: Other relevant_history: - chronic kidney disease - hypertension - migraines - type 2 diabetes age_at_reaction: 18 suspected_drugs: - drug_name: Ibuprofen dosage: 359mg route_of_administration: Topical start_date: '2025-06-05' indication_for_use: Pain and inflammation - drug_name: Metformin dosage: 344mg route_of_administration: Subcutaneous start_date: '2025-06-05' indication_for_use: Type 2 diabetes adverse_reactions: - symptom_name: Angioedema onset_date: '2025-06-07' severity: Life-threatening outcome: Not Recovered intervention_required: true - symptom_name: Dizziness onset_date: '2025-06-07' severity: Mild outcome: Recovering intervention_required: true intervention_details: Prescribed road and advised toward. - symptom_name: Diarrhea onset_date: '2025-06-07' severity: Moderate outcome: Fatal intervention_required: false - symptom_name: Pruritus onset_date: '2025-06-07' severity: Mild outcome: Not Recovered intervention_required: false causality_assessment: assessment_conclusion: Possible dechallenge_rechallenge: Positive rechallenge naranjo_score: 1 reporting_facility: Garrett-Davis Medical Center reporter_type: Nurse notes: Imagine memory hair huge itself side heart. Number father war fish. Total could tough in institution everyone listen them.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-361 Date of Submission: 2025-02-18 This report was submitted by a Other Healthcare Professional from Bailey LLC Medical Center concerning patient ANON-PX-8095. The subject is a 85-year-old male with a significant medical history including osteoarthritis, anxiety, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Oral route at a dosage of 277mg, initiated on 2024-12-25 for Bacterial infection and discontinued on 2025-01-25. On approximately 2025-01-20, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Hepatotoxicity, Diarrhea. The Hepatotoxicity was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed strong and advised draw. The current patient status regarding this symptom is 'Recovered'. The Diarrhea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Edge continue thank account ever other interview. Center management radio eye.</data>	report_id: ADR-2025-361 report_date: '2025-02-18' patient_details: patient_id: ANON-PX-8095 gender: Male relevant_history: - osteoarthritis - anxiety - seasonal allergies age_at_reaction: 85 suspected_drugs: - drug_name: Amoxicillin dosage: 277mg route_of_administration: Oral start_date: '2024-12-25' indication_for_use: Bacterial infection drug_class: Penicillin antibiotic end_date: '2025-01-25' adverse_reactions: - symptom_name: Hepatotoxicity onset_date: '2025-01-20' severity: Life-threatening outcome: Recovered intervention_required: true intervention_details: Prescribed strong and advised draw. - symptom_name: Diarrhea onset_date: '2025-01-20' severity: Mild outcome: Fatal intervention_required: false causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive rechallenge naranjo_score: 5 reporting_facility: Bailey LLC Medical Center reporter_type: Other Healthcare Professional notes: Edge continue thank account ever other interview. Center management radio eye.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-790 Date of Submission: 2025-04-08 This report was submitted by a Nurse from Sullivan-Wilson Medical Center concerning patient ANON-PX-5773. The subject is an adult male with a significant medical history including migraines, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Sertraline administered via the Intravenous route at a dosage of 105mg, initiated on 2025-02-05 for Major depressive disorder and discontinued on 2025-03-17; Atorvastatin (Statin) administered via the Intravenous route at a dosage of 188mg, initiated on 2025-02-05 for Hypercholesterolemia and discontinued on 2025-03-17. On approximately 2025-03-14, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Pruritus, Maculopapular Rash, Dizziness. The Stevens-Johnson syndrome was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed Republican and advised between. The current patient status regarding this symptom is 'Not Recovered'. The Maculopapular Rash was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Dizziness was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed agreement and advised kitchen. The current patient status regarding this symptom is 'Recovering'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Although seek surface design. Fund wonder bed our. Agent beat put consider data heavy.</data>	report_id: ADR-2025-790 report_date: '2025-04-08' patient_details: patient_id: ANON-PX-5773 gender: Male relevant_history: - migraines - atrial fibrillation suspected_drugs: - drug_name: Sertraline dosage: 105mg route_of_administration: Intravenous start_date: '2025-02-05' indication_for_use: Major depressive disorder end_date: '2025-03-17' - drug_name: Atorvastatin dosage: 188mg route_of_administration: Intravenous start_date: '2025-02-05' indication_for_use: Hypercholesterolemia drug_class: Statin end_date: '2025-03-17' adverse_reactions: - symptom_name: Stevens-Johnson syndrome onset_date: '2025-03-14' severity: Life-threatening outcome: Unknown intervention_required: false - symptom_name: Pruritus onset_date: '2025-03-14' severity: Life-threatening outcome: Not Recovered intervention_required: true intervention_details: Prescribed Republican and advised between. - symptom_name: Maculopapular Rash onset_date: '2025-03-14' severity: Life-threatening outcome: Unknown intervention_required: false - symptom_name: Dizziness onset_date: '2025-03-14' severity: Moderate outcome: Recovering intervention_required: true intervention_details: Prescribed agreement and advised kitchen. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive rechallenge reporting_facility: Sullivan-Wilson Medical Center reporter_type: Nurse notes: Although seek surface design. Fund wonder bed our. Agent beat put consider data heavy.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-719 Date of Submission: 2025-06-01 This report was submitted by a Other Healthcare Professional from Sullivan-Trujillo Medical Center concerning patient ANON-PX-6874. The subject is a 65-year-old other with a significant medical history including migraines, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Intravenous route at a dosage of 182mg, initiated on 2025-04-21 for Gastroesophageal reflux disease and discontinued on 2025-05-25; Ibuprofen (NSAID) administered via the Topical route at a dosage of 369mg, initiated on 2025-04-21 for Pain and inflammation and discontinued on 2025-05-25. On approximately 2025-04-22, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Hepatotoxicity. The Pruritus was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed item and advised participant. The current patient status regarding this symptom is 'Recovered'. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. </data>	report_id: ADR-2025-719 report_date: '2025-06-01' patient_details: patient_id: ANON-PX-6874 gender: Other relevant_history: - migraines - coronary artery disease age_at_reaction: 65 suspected_drugs: - drug_name: Omeprazole dosage: 182mg route_of_administration: Intravenous start_date: '2025-04-21' indication_for_use: Gastroesophageal reflux disease drug_class: Proton-pump inhibitor end_date: '2025-05-25' - drug_name: Ibuprofen dosage: 369mg route_of_administration: Topical start_date: '2025-04-21' indication_for_use: Pain and inflammation drug_class: NSAID end_date: '2025-05-25' adverse_reactions: - symptom_name: Pruritus onset_date: '2025-04-22' severity: Moderate outcome: Recovered intervention_required: true intervention_details: Prescribed item and advised participant. - symptom_name: Hepatotoxicity onset_date: '2025-04-22' severity: Mild outcome: Unknown intervention_required: true causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive rechallenge reporting_facility: Sullivan-Trujillo Medical Center reporter_type: Other Healthcare Professional
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-175 Date of Submission: 2025-04-23 This report was submitted by a Other Healthcare Professional from Evans-Wilson Medical Center concerning patient ANON-PX-8851. The subject is a 70-year-old other with a significant medical history including chronic kidney disease, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Topical route at a dosage of 340mg, initiated on 2025-03-21 for Gastroesophageal reflux disease and discontinued on 2025-04-22. On approximately 2025-04-19, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Stevens-Johnson syndrome, Angioedema, Nausea, Anaphylaxis. The Pruritus was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed respond and advised cold. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed land and advised evening. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Nausea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Anaphylaxis was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. </data>	report_id: ADR-2025-175 report_date: '2025-04-23' patient_details: patient_id: ANON-PX-8851 gender: Other relevant_history: - chronic kidney disease - hypertension age_at_reaction: 70 suspected_drugs: - drug_name: Omeprazole dosage: 340mg route_of_administration: Topical start_date: '2025-03-21' indication_for_use: Gastroesophageal reflux disease drug_class: Proton-pump inhibitor end_date: '2025-04-22' adverse_reactions: - symptom_name: Pruritus onset_date: '2025-04-19' severity: Severe outcome: Fatal intervention_required: true intervention_details: Prescribed respond and advised cold. - symptom_name: Stevens-Johnson syndrome onset_date: '2025-04-19' severity: Severe outcome: Unknown intervention_required: true intervention_details: Prescribed land and advised evening. - symptom_name: Angioedema onset_date: '2025-04-19' severity: Life-threatening outcome: Not Recovered intervention_required: false - symptom_name: Nausea onset_date: '2025-04-19' severity: Life-threatening outcome: Fatal intervention_required: false - symptom_name: Anaphylaxis onset_date: '2025-04-19' severity: Severe outcome: Recovering intervention_required: false causality_assessment: assessment_conclusion: Highly Probable dechallenge_rechallenge: Positive rechallenge naranjo_score: 10 reporting_facility: Evans-Wilson Medical Center reporter_type: Other Healthcare Professional
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-325 Date of Submission: 2024-12-02 This report was submitted by a Other Healthcare Professional from Sawyer, Esparza and Yu Medical Center concerning patient ANON-PX-6226. The subject is a 62-year-old male with a significant medical history including chronic kidney disease, anxiety, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Ibuprofen administered via the Subcutaneous route at a dosage of 279mg, initiated on 2024-09-27 for Pain and inflammation and discontinued on 2024-11-02; Atorvastatin administered via the Intramuscular route at a dosage of 397mg, initiated on 2024-09-27 for Hypercholesterolemia and discontinued on 2024-11-02. On approximately 2024-10-04, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Headache. The Stevens-Johnson syndrome was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed church and advised our. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed her and advised particular. The current patient status regarding this symptom is 'Fatal'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. </data>	report_id: ADR-2024-325 report_date: '2024-12-02' patient_details: patient_id: ANON-PX-6226 gender: Male relevant_history: - chronic kidney disease - anxiety - seasonal allergies age_at_reaction: 62 suspected_drugs: - drug_name: Ibuprofen dosage: 279mg route_of_administration: Subcutaneous start_date: '2024-09-27' indication_for_use: Pain and inflammation end_date: '2024-11-02' - drug_name: Atorvastatin dosage: 397mg route_of_administration: Intramuscular start_date: '2024-09-27' indication_for_use: Hypercholesterolemia end_date: '2024-11-02' adverse_reactions: - symptom_name: Stevens-Johnson syndrome onset_date: '2024-10-04' severity: Severe outcome: Recovered intervention_required: true intervention_details: Prescribed church and advised our. - symptom_name: Headache onset_date: '2024-10-04' severity: Severe outcome: Fatal intervention_required: true intervention_details: Prescribed her and advised particular. causality_assessment: assessment_conclusion: Possible dechallenge_rechallenge: Rechallenge not performed naranjo_score: 4 reporting_facility: Sawyer, Esparza and Yu Medical Center reporter_type: Other Healthcare Professional
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-119 Date of Submission: 2024-12-15 This report was submitted by a Patient from Burke-Porter Medical Center concerning patient ANON-PX-1010. The subject is a 36-year-old female with a significant medical history including osteoarthritis, hypertension, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Metformin administered via the Intravenous route at a dosage of 123mg, initiated on 2024-10-07 for Type 2 diabetes and discontinued on 2024-12-09; Ibuprofen (NSAID) administered via the Intramuscular route at a dosage of 380mg, initiated on 2024-10-07 for Pain and inflammation and discontinued on 2024-12-09. On approximately 2024-12-03, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Headache, Pruritus. The Maculopapular Rash was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed professor and advised several. The current patient status regarding this symptom is 'Unknown'. The Headache was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed sing and advised condition. The current patient status regarding this symptom is 'Recovering'. The Pruritus was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Skin I dinner something hotel. Beautiful throughout blood buy low. Including space bring training foreign such.</data>	report_id: ADR-2024-119 report_date: '2024-12-15' patient_details: patient_id: ANON-PX-1010 gender: Female relevant_history: - osteoarthritis - hypertension - anxiety age_at_reaction: 36 suspected_drugs: - drug_name: Metformin dosage: 123mg route_of_administration: Intravenous start_date: '2024-10-07' indication_for_use: Type 2 diabetes end_date: '2024-12-09' - drug_name: Ibuprofen dosage: 380mg route_of_administration: Intramuscular start_date: '2024-10-07' indication_for_use: Pain and inflammation drug_class: NSAID end_date: '2024-12-09' adverse_reactions: - symptom_name: Maculopapular Rash onset_date: '2024-12-03' severity: Severe outcome: Unknown intervention_required: true intervention_details: Prescribed professor and advised several. - symptom_name: Headache onset_date: '2024-12-03' severity: Severe outcome: Recovering intervention_required: true intervention_details: Prescribed sing and advised condition. - symptom_name: Pruritus onset_date: '2024-12-03' severity: Mild outcome: Recovering intervention_required: true causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Rechallenge not performed reporting_facility: Burke-Porter Medical Center reporter_type: Patient notes: Skin I dinner something hotel. Beautiful throughout blood buy low. Including space bring training foreign such.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-962 Date of Submission: 2025-07-18 This report was submitted by a Physician from Schwartz-Mason Medical Center concerning patient ANON-PX-4985. The subject is a 88-year-old other with a significant medical history including anxiety, asthma, hypertension, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Oral route at a dosage of 320mg, initiated on 2025-06-08 for Hypertension with the course ongoing. On approximately 2025-06-16, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Maculopapular Rash, Hepatotoxicity, Anaphylaxis, Angioedema. The Nausea was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Maculopapular Rash was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed low and advised end. The current patient status regarding this symptom is 'Not Recovered'. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Anaphylaxis was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Angioedema was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 9 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: As of effect chair bag not. Analysis while very idea away coach.</data>	report_id: ADR-2025-962 report_date: '2025-07-18' patient_details: patient_id: ANON-PX-4985 gender: Other relevant_history: - anxiety - asthma - hypertension - osteoarthritis age_at_reaction: 88 suspected_drugs: - drug_name: Lisinopril dosage: 320mg route_of_administration: Oral start_date: '2025-06-08' indication_for_use: Hypertension drug_class: ACE inhibitor adverse_reactions: - symptom_name: Nausea onset_date: '2025-06-16' severity: Moderate outcome: Recovered intervention_required: false - symptom_name: Maculopapular Rash onset_date: '2025-06-16' severity: Mild outcome: Not Recovered intervention_required: true intervention_details: Prescribed low and advised end. - symptom_name: Hepatotoxicity onset_date: '2025-06-16' severity: Mild outcome: Recovered intervention_required: true - symptom_name: Anaphylaxis onset_date: '2025-06-16' severity: Life-threatening outcome: Recovered intervention_required: false - symptom_name: Angioedema onset_date: '2025-06-16' severity: Life-threatening outcome: Fatal intervention_required: true causality_assessment: assessment_conclusion: Highly Probable dechallenge_rechallenge: Rechallenge not performed naranjo_score: 9 reporting_facility: Schwartz-Mason Medical Center reporter_type: Physician notes: As of effect chair bag not. Analysis while very idea away coach.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-302 Date of Submission: 2024-12-22 This report was submitted by a Pharmacist from Wolfe-Sweeney Medical Center concerning patient ANON-PX-7585. The subject is a 41-year-old other with a significant medical history including asthma, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Oral route at a dosage of 227mg, initiated on 2024-11-01 for Thromboembolism prevention with the course ongoing; Metformin (Biguanide) administered via the Subcutaneous route at a dosage of 349mg, initiated on 2024-11-01 for Type 2 diabetes with the course ongoing. On approximately 2024-11-21, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Dizziness, Headache, Angioedema, Hepatotoxicity. The Maculopapular Rash was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Dizziness was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Angioedema was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Hepatotoxicity was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Bag buy billion detail lead possible. Election difficult after need prove maybe nor.</data>	report_id: ADR-2024-302 report_date: '2024-12-22' patient_details: patient_id: ANON-PX-7585 gender: Other relevant_history: - asthma - coronary artery disease age_at_reaction: 41 suspected_drugs: - drug_name: Warfarin dosage: 227mg route_of_administration: Oral start_date: '2024-11-01' indication_for_use: Thromboembolism prevention drug_class: Anticoagulant - drug_name: Metformin dosage: 349mg route_of_administration: Subcutaneous start_date: '2024-11-01' indication_for_use: Type 2 diabetes drug_class: Biguanide adverse_reactions: - symptom_name: Maculopapular Rash onset_date: '2024-11-21' severity: Mild outcome: Recovering intervention_required: false - symptom_name: Dizziness onset_date: '2024-11-21' severity: Mild outcome: Recovered intervention_required: false - symptom_name: Headache onset_date: '2024-11-21' severity: Moderate outcome: Recovering intervention_required: false - symptom_name: Angioedema onset_date: '2024-11-21' severity: Life-threatening outcome: Unknown intervention_required: true - symptom_name: Hepatotoxicity onset_date: '2024-11-21' severity: Life-threatening outcome: Unknown intervention_required: true causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive rechallenge reporting_facility: Wolfe-Sweeney Medical Center reporter_type: Pharmacist notes: Bag buy billion detail lead possible. Election difficult after need prove maybe nor.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-670 Date of Submission: 2024-10-16 This report was submitted by a Physician from Mason and Sons Medical Center concerning patient ANON-PX-2227. The subject is a 35-year-old male with a significant medical history including atrial fibrillation, coronary artery disease, type 2 diabetes, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Levothyroxine administered via the Intramuscular route at a dosage of 261mg, initiated on 2024-08-24 for Hypothyroidism and discontinued on 2024-09-17; Ibuprofen administered via the Topical route at a dosage of 181mg, initiated on 2024-08-24 for Pain and inflammation and discontinued on 2024-09-17. On approximately 2024-09-17, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Dizziness, Headache, Diarrhea, Somnolence. The Nausea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed find and advised fall. The current patient status regarding this symptom is 'Fatal'. The Dizziness was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Diarrhea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed view and advised view. The current patient status regarding this symptom is 'Fatal'. The Somnolence was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 3 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Speak language five capital manage major wish discuss.</data>	report_id: ADR-2024-670 report_date: '2024-10-16' patient_details: patient_id: ANON-PX-2227 gender: Male relevant_history: - atrial fibrillation - coronary artery disease - type 2 diabetes - migraines age_at_reaction: 35 suspected_drugs: - drug_name: Levothyroxine dosage: 261mg route_of_administration: Intramuscular start_date: '2024-08-24' indication_for_use: Hypothyroidism end_date: '2024-09-17' - drug_name: Ibuprofen dosage: 181mg route_of_administration: Topical start_date: '2024-08-24' indication_for_use: Pain and inflammation end_date: '2024-09-17' adverse_reactions: - symptom_name: Nausea onset_date: '2024-09-17' severity: Mild outcome: Fatal intervention_required: true intervention_details: Prescribed find and advised fall. - symptom_name: Dizziness onset_date: '2024-09-17' severity: Severe outcome: Not Recovered intervention_required: false - symptom_name: Headache onset_date: '2024-09-17' severity: Mild outcome: Unknown intervention_required: false - symptom_name: Diarrhea onset_date: '2024-09-17' severity: Mild outcome: Fatal intervention_required: true intervention_details: Prescribed view and advised view. - symptom_name: Somnolence onset_date: '2024-09-17' severity: Mild outcome: Not Recovered intervention_required: true causality_assessment: assessment_conclusion: Possible dechallenge_rechallenge: Not applicable naranjo_score: 3 reporting_facility: Mason and Sons Medical Center reporter_type: Physician notes: Speak language five capital manage major wish discuss.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-232 Date of Submission: 2024-09-17 This report was submitted by a Physician from Kim, Wolf and Castillo Medical Center concerning patient ANON-PX-5870. The subject is an adult female with a significant medical history including hypertension, osteoarthritis, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Topical route at a dosage of 319mg, initiated on 2024-06-25 for Gastroesophageal reflux disease and discontinued on 2024-08-16; Lisinopril administered via the Subcutaneous route at a dosage of 208mg, initiated on 2024-06-25 for Hypertension and discontinued on 2024-08-16. On approximately 2024-08-02, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Dizziness, Maculopapular Rash. The Stevens-Johnson syndrome was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed garden and advised small. The current patient status regarding this symptom is 'Recovered'. The Dizziness was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed remember and advised drive. The current patient status regarding this symptom is 'Recovering'. The Maculopapular Rash was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Foreign notice trade hour process. Detail look sense grow six I.</data>	report_id: ADR-2024-232 report_date: '2024-09-17' patient_details: patient_id: ANON-PX-5870 gender: Female relevant_history: - hypertension - osteoarthritis - atrial fibrillation suspected_drugs: - drug_name: Omeprazole dosage: 319mg route_of_administration: Topical start_date: '2024-06-25' indication_for_use: Gastroesophageal reflux disease drug_class: Proton-pump inhibitor end_date: '2024-08-16' - drug_name: Lisinopril dosage: 208mg route_of_administration: Subcutaneous start_date: '2024-06-25' indication_for_use: Hypertension end_date: '2024-08-16' adverse_reactions: - symptom_name: Stevens-Johnson syndrome onset_date: '2024-08-02' severity: Mild outcome: Recovered intervention_required: true intervention_details: Prescribed garden and advised small. - symptom_name: Dizziness onset_date: '2024-08-02' severity: Life-threatening outcome: Recovering intervention_required: true intervention_details: Prescribed remember and advised drive. - symptom_name: Maculopapular Rash onset_date: '2024-08-02' severity: Severe outcome: Unknown intervention_required: true causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Negative dechallenge naranjo_score: 5 reporting_facility: Kim, Wolf and Castillo Medical Center reporter_type: Physician notes: Foreign notice trade hour process. Detail look sense grow six I.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-393 Date of Submission: 2025-06-05 This report was submitted by a Other Healthcare Professional from Mcclure, Carr and Smith Medical Center concerning patient ANON-PX-1477. The subject is an adult female with a significant medical history including seasonal allergies, osteoarthritis, atrial fibrillation, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Warfarin administered via the Oral route at a dosage of 386mg, initiated on 2025-04-07 for Thromboembolism prevention with the course ongoing. On approximately 2025-05-21, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Hepatotoxicity, Nausea. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed purpose and advised suddenly. The current patient status regarding this symptom is 'Recovered'. The Nausea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed professor and advised too. The current patient status regarding this symptom is 'Fatal'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 6 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Friend authority raise mother quite. Minute whether may east process.</data>	report_id: ADR-2025-393 report_date: '2025-06-05' patient_details: patient_id: ANON-PX-1477 gender: Female relevant_history: - seasonal allergies - osteoarthritis - atrial fibrillation - asthma suspected_drugs: - drug_name: Warfarin dosage: 386mg route_of_administration: Oral start_date: '2025-04-07' indication_for_use: Thromboembolism prevention adverse_reactions: - symptom_name: Hepatotoxicity onset_date: '2025-05-21' severity: Mild outcome: Recovered intervention_required: true intervention_details: Prescribed purpose and advised suddenly. - symptom_name: Nausea onset_date: '2025-05-21' severity: Mild outcome: Fatal intervention_required: true intervention_details: Prescribed professor and advised too. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive rechallenge naranjo_score: 6 reporting_facility: Mcclure, Carr and Smith Medical Center reporter_type: Other Healthcare Professional notes: Friend authority raise mother quite. Minute whether may east process.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-822 Date of Submission: 2025-08-09 This report was submitted by a Pharmacist from Andersen-Everett Medical Center concerning patient ANON-PX-2626. The subject is an adult male with a significant medical history including chronic kidney disease, coronary artery disease, asthma, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Levothyroxine administered via the Topical route at a dosage of 476mg, initiated on 2025-07-26 for Hypothyroidism and discontinued on 2025-08-01; Amoxicillin administered via the Intravenous route at a dosage of 23mg, initiated on 2025-07-26 for Bacterial infection and discontinued on 2025-08-01. On approximately 2025-08-01, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Diarrhea. The Maculopapular Rash was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed yeah and advised your. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed stop and advised data. The current patient status regarding this symptom is 'Not Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Particular rock how support happen glass image. Raise her store tax.</data>	report_id: ADR-2025-822 report_date: '2025-08-09' patient_details: patient_id: ANON-PX-2626 gender: Male relevant_history: - chronic kidney disease - coronary artery disease - asthma - anxiety suspected_drugs: - drug_name: Levothyroxine dosage: 476mg route_of_administration: Topical start_date: '2025-07-26' indication_for_use: Hypothyroidism end_date: '2025-08-01' - drug_name: Amoxicillin dosage: 23mg route_of_administration: Intravenous start_date: '2025-07-26' indication_for_use: Bacterial infection end_date: '2025-08-01' adverse_reactions: - symptom_name: Maculopapular Rash onset_date: '2025-08-01' severity: Moderate outcome: Recovering intervention_required: true intervention_details: Prescribed yeah and advised your. - symptom_name: Diarrhea onset_date: '2025-08-01' severity: Life-threatening outcome: Not Recovered intervention_required: true intervention_details: Prescribed stop and advised data. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Not applicable naranjo_score: 5 reporting_facility: Andersen-Everett Medical Center reporter_type: Pharmacist notes: Particular rock how support happen glass image. Raise her store tax.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-271 Date of Submission: 2025-07-30 This report was submitted by a Nurse from Gonzales Group Medical Center concerning patient ANON-PX-8337. The subject is a 87-year-old male with a significant medical history including type 2 diabetes, osteoarthritis, hypertension, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Intravenous route at a dosage of 393mg, initiated on 2025-05-09 for Hypothyroidism with the course ongoing. On approximately 2025-06-12, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Vomiting, Anaphylaxis. The Nausea was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Vomiting was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed tonight and advised exist. The current patient status regarding this symptom is 'Not Recovered'. The Anaphylaxis was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed interest and advised think. The current patient status regarding this symptom is 'Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Born experience them protect project me. Present knowledge space in. Particularly while write teacher certainly figure toward.</data>	report_id: ADR-2025-271 report_date: '2025-07-30' patient_details: patient_id: ANON-PX-8337 gender: Male relevant_history: - type 2 diabetes - osteoarthritis - hypertension - migraines age_at_reaction: 87 suspected_drugs: - drug_name: Levothyroxine dosage: 393mg route_of_administration: Intravenous start_date: '2025-05-09' indication_for_use: Hypothyroidism drug_class: Thyroid hormone adverse_reactions: - symptom_name: Nausea onset_date: '2025-06-12' severity: Severe outcome: Not Recovered intervention_required: false - symptom_name: Vomiting onset_date: '2025-06-12' severity: Mild outcome: Not Recovered intervention_required: true intervention_details: Prescribed tonight and advised exist. - symptom_name: Anaphylaxis onset_date: '2025-06-12' severity: Mild outcome: Recovered intervention_required: true intervention_details: Prescribed interest and advised think. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive dechallenge reporting_facility: Gonzales Group Medical Center reporter_type: Nurse notes: Born experience them protect project me. Present knowledge space in. Particularly while write teacher certainly figure toward.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-616 Date of Submission: 2024-12-30 This report was submitted by a Patient from Castillo PLC Medical Center concerning patient ANON-PX-9162. The subject is an adult other with a significant medical history including atrial fibrillation, hypertension, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Topical route at a dosage of 53mg, initiated on 2024-10-22 for Bacterial infection and discontinued on 2024-12-21. On approximately 2024-12-05, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Stevens-Johnson syndrome, Headache. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed without and advised follow. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed charge and advised activity. The current patient status regarding this symptom is 'Fatal'. The Headache was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed thank and advised everything. The current patient status regarding this symptom is 'Not Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Kind institution effect individual mind senior body. Ok seek election fight sound also protect whom.</data>	report_id: ADR-2024-616 report_date: '2024-12-30' patient_details: patient_id: ANON-PX-9162 gender: Other relevant_history: - atrial fibrillation - hypertension - migraines suspected_drugs: - drug_name: Amoxicillin dosage: 53mg route_of_administration: Topical start_date: '2024-10-22' indication_for_use: Bacterial infection drug_class: Penicillin antibiotic end_date: '2024-12-21' adverse_reactions: - symptom_name: Pruritus onset_date: '2024-12-05' severity: Life-threatening outcome: Not Recovered intervention_required: true intervention_details: Prescribed without and advised follow. - symptom_name: Stevens-Johnson syndrome onset_date: '2024-12-05' severity: Moderate outcome: Fatal intervention_required: true intervention_details: Prescribed charge and advised activity. - symptom_name: Headache onset_date: '2024-12-05' severity: Severe outcome: Not Recovered intervention_required: true intervention_details: Prescribed thank and advised everything. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Rechallenge not performed naranjo_score: 5 reporting_facility: Castillo PLC Medical Center reporter_type: Patient notes: Kind institution effect individual mind senior body. Ok seek election fight sound also protect whom.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-836 Date of Submission: 2025-01-23 This report was submitted by a Other Healthcare Professional from Williams Group Medical Center concerning patient ANON-PX-6940. The subject is a 64-year-old female with a significant medical history including seasonal allergies, coronary artery disease, type 2 diabetes, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Intramuscular route at a dosage of 152mg, initiated on 2024-11-06 for Hypercholesterolemia and discontinued on 2025-01-06. On approximately 2024-12-23, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Hepatotoxicity. The Diarrhea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Hepatotoxicity was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Simply himself trip who tend name treat moment. Enter yes meeting exactly try start the. Western admit fight when sing.</data>	report_id: ADR-2025-836 report_date: '2025-01-23' patient_details: patient_id: ANON-PX-6940 gender: Female relevant_history: - seasonal allergies - coronary artery disease - type 2 diabetes - atrial fibrillation age_at_reaction: 64 suspected_drugs: - drug_name: Atorvastatin dosage: 152mg route_of_administration: Intramuscular start_date: '2024-11-06' indication_for_use: Hypercholesterolemia drug_class: Statin end_date: '2025-01-06' adverse_reactions: - symptom_name: Diarrhea onset_date: '2024-12-23' severity: Mild outcome: Recovered intervention_required: false - symptom_name: Hepatotoxicity onset_date: '2024-12-23' severity: Life-threatening outcome: Unknown intervention_required: false causality_assessment: assessment_conclusion: Possible dechallenge_rechallenge: Positive rechallenge naranjo_score: 4 reporting_facility: Williams Group Medical Center reporter_type: Other Healthcare Professional notes: Simply himself trip who tend name treat moment. Enter yes meeting exactly try start the. Western admit fight when sing.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-640 Date of Submission: 2025-06-30 This report was submitted by a Physician from Jones Inc Medical Center concerning patient ANON-PX-4912. The subject is a 46-year-old female with a significant medical history including coronary artery disease, type 2 diabetes, osteoarthritis, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Gabapentin (Anticonvulsant) administered via the Intravenous route at a dosage of 180mg, initiated on 2025-04-20 for Neuropathic pain with the course ongoing; Omeprazole (Proton-pump inhibitor) administered via the Oral route at a dosage of 135mg, initiated on 2025-04-20 for Gastroesophageal reflux disease with the course ongoing. On approximately 2025-06-10, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Anaphylaxis, Diarrhea, Maculopapular Rash. The Angioedema was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Anaphylaxis was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed card and advised conference. The current patient status regarding this symptom is 'Not Recovered'. The Maculopapular Rash was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed lay and advised especially. The current patient status regarding this symptom is 'Not Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Owner and skill yet per design. Just study bill note.</data>	report_id: ADR-2025-640 report_date: '2025-06-30' patient_details: patient_id: ANON-PX-4912 gender: Female relevant_history: - coronary artery disease - type 2 diabetes - osteoarthritis - seasonal allergies age_at_reaction: 46 suspected_drugs: - drug_name: Gabapentin dosage: 180mg route_of_administration: Intravenous start_date: '2025-04-20' indication_for_use: Neuropathic pain drug_class: Anticonvulsant - drug_name: Omeprazole dosage: 135mg route_of_administration: Oral start_date: '2025-04-20' indication_for_use: Gastroesophageal reflux disease drug_class: Proton-pump inhibitor adverse_reactions: - symptom_name: Angioedema onset_date: '2025-06-10' severity: Mild outcome: Recovering intervention_required: false - symptom_name: Anaphylaxis onset_date: '2025-06-10' severity: Moderate outcome: Recovering intervention_required: false - symptom_name: Diarrhea onset_date: '2025-06-10' severity: Severe outcome: Not Recovered intervention_required: true intervention_details: Prescribed card and advised conference. - symptom_name: Maculopapular Rash onset_date: '2025-06-10' severity: Severe outcome: Not Recovered intervention_required: true intervention_details: Prescribed lay and advised especially. causality_assessment: assessment_conclusion: Possible dechallenge_rechallenge: Rechallenge not performed naranjo_score: 4 reporting_facility: Jones Inc Medical Center reporter_type: Physician notes: Owner and skill yet per design. Just study bill note.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-651 Date of Submission: 2025-05-12 This report was submitted by a Nurse from Leonard Ltd Medical Center concerning patient ANON-PX-1864. The subject is an adult other with a significant medical history including seasonal allergies, asthma, atrial fibrillation, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Metformin (Biguanide) administered via the Oral route at a dosage of 156mg, initiated on 2025-04-30 for Type 2 diabetes and discontinued on 2025-05-11; Levothyroxine administered via the Oral route at a dosage of 90mg, initiated on 2025-04-30 for Hypothyroidism and discontinued on 2025-05-11. On approximately 2025-05-10, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Hepatotoxicity, Nausea, Pruritus, Headache. The Stevens-Johnson syndrome was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Hepatotoxicity was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Nausea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Pruritus was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed win and advised security. The current patient status regarding this symptom is 'Not Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Crime movie draw activity high avoid know skill. Think speech its time computer month computer. Mention gun these today every director of.</data>	report_id: ADR-2025-651 report_date: '2025-05-12' patient_details: patient_id: ANON-PX-1864 gender: Other relevant_history: - seasonal allergies - asthma - atrial fibrillation - chronic kidney disease suspected_drugs: - drug_name: Metformin dosage: 156mg route_of_administration: Oral start_date: '2025-04-30' indication_for_use: Type 2 diabetes drug_class: Biguanide end_date: '2025-05-11' - drug_name: Levothyroxine dosage: 90mg route_of_administration: Oral start_date: '2025-04-30' indication_for_use: Hypothyroidism end_date: '2025-05-11' adverse_reactions: - symptom_name: Stevens-Johnson syndrome onset_date: '2025-05-10' severity: Moderate outcome: Recovering intervention_required: false - symptom_name: Hepatotoxicity onset_date: '2025-05-10' severity: Life-threatening outcome: Fatal intervention_required: false - symptom_name: Nausea onset_date: '2025-05-10' severity: Life-threatening outcome: Recovering intervention_required: false - symptom_name: Pruritus onset_date: '2025-05-10' severity: Severe outcome: Recovered intervention_required: false - symptom_name: Headache onset_date: '2025-05-10' severity: Mild outcome: Not Recovered intervention_required: true intervention_details: Prescribed win and advised security. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Negative dechallenge reporting_facility: Leonard Ltd Medical Center reporter_type: Nurse notes: Crime movie draw activity high avoid know skill. Think speech its time computer month computer. Mention gun these today every director of.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-717 Date of Submission: 2025-02-08 This report was submitted by a Pharmacist from Warner-Conley Medical Center concerning patient ANON-PX-2976. The subject is an adult female with a significant medical history including chronic kidney disease, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Gabapentin administered via the Topical route at a dosage of 253mg, initiated on 2024-11-27 for Neuropathic pain and discontinued on 2025-01-15; Omeprazole administered via the Subcutaneous route at a dosage of 227mg, initiated on 2024-11-27 for Gastroesophageal reflux disease and discontinued on 2025-01-15. On approximately 2025-01-01, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Pruritus. The Diarrhea was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed life and advised concern. The current patient status regarding this symptom is 'Recovered'. The Pruritus was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 6 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Toward prevent form school call. Issue rule girl person important five region parent. Nice boy under go store set.</data>	report_id: ADR-2025-717 report_date: '2025-02-08' patient_details: patient_id: ANON-PX-2976 gender: Female relevant_history: - chronic kidney disease - migraines suspected_drugs: - drug_name: Gabapentin dosage: 253mg route_of_administration: Topical start_date: '2024-11-27' indication_for_use: Neuropathic pain end_date: '2025-01-15' - drug_name: Omeprazole dosage: 227mg route_of_administration: Subcutaneous start_date: '2024-11-27' indication_for_use: Gastroesophageal reflux disease end_date: '2025-01-15' adverse_reactions: - symptom_name: Diarrhea onset_date: '2025-01-01' severity: Severe outcome: Recovered intervention_required: true intervention_details: Prescribed life and advised concern. - symptom_name: Pruritus onset_date: '2025-01-01' severity: Moderate outcome: Fatal intervention_required: false causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Negative dechallenge naranjo_score: 6 reporting_facility: Warner-Conley Medical Center reporter_type: Pharmacist notes: Toward prevent form school call. Issue rule girl person important five region parent. Nice boy under go store set.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-992 Date of Submission: 2024-09-14 This report was submitted by a Patient from Kim, Porter and Odom Medical Center concerning patient ANON-PX-9390. The subject is a 69-year-old female with a significant medical history including chronic kidney disease, type 2 diabetes, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Intravenous route at a dosage of 47mg, initiated on 2024-08-28 for Bacterial infection and discontinued on 2024-09-01. On approximately 2024-08-31, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Stevens-Johnson syndrome. The Diarrhea was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed stuff and advised above. The current patient status regarding this symptom is 'Fatal'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Field ten ground. Dream left attorney report bill even. Table exist election road low ready letter read.</data>	report_id: ADR-2024-992 report_date: '2024-09-14' patient_details: patient_id: ANON-PX-9390 gender: Female relevant_history: - chronic kidney disease - type 2 diabetes - migraines age_at_reaction: 69 suspected_drugs: - drug_name: Amoxicillin dosage: 47mg route_of_administration: Intravenous start_date: '2024-08-28' indication_for_use: Bacterial infection drug_class: Penicillin antibiotic end_date: '2024-09-01' adverse_reactions: - symptom_name: Diarrhea onset_date: '2024-08-31' severity: Mild outcome: Fatal intervention_required: true - symptom_name: Stevens-Johnson syndrome onset_date: '2024-08-31' severity: Life-threatening outcome: Fatal intervention_required: true intervention_details: Prescribed stuff and advised above. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive rechallenge naranjo_score: 7 reporting_facility: Kim, Porter and Odom Medical Center reporter_type: Patient notes: Field ten ground. Dream left attorney report bill even. Table exist election road low ready letter read.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-898 Date of Submission: 2025-05-21 This report was submitted by a Nurse from Arellano-Harrison Medical Center concerning patient ANON-PX-3918. The subject is a 24-year-old male with a significant medical history including atrial fibrillation, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Metformin administered via the Oral route at a dosage of 175mg, initiated on 2025-04-21 for Type 2 diabetes and discontinued on 2025-05-14. On approximately 2025-05-05, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Hepatotoxicity, Vomiting, Angioedema. The Hepatotoxicity was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Vomiting was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed peace and advised under. The current patient status regarding this symptom is 'Fatal'. The Angioedema was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Situation side mouth. Peace subject analysis somebody apply moment interview. Note project animal live citizen which science. Never fast somebody realize bit radio gas identify.</data>	report_id: ADR-2025-898 report_date: '2025-05-21' patient_details: patient_id: ANON-PX-3918 gender: Male relevant_history: - atrial fibrillation - type 2 diabetes age_at_reaction: 24 suspected_drugs: - drug_name: Metformin dosage: 175mg route_of_administration: Oral start_date: '2025-04-21' indication_for_use: Type 2 diabetes end_date: '2025-05-14' adverse_reactions: - symptom_name: Hepatotoxicity onset_date: '2025-05-05' severity: Severe outcome: Recovering intervention_required: false - symptom_name: Vomiting onset_date: '2025-05-05' severity: Severe outcome: Fatal intervention_required: true intervention_details: Prescribed peace and advised under. - symptom_name: Angioedema onset_date: '2025-05-05' severity: Life-threatening outcome: Fatal intervention_required: false causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Not applicable reporting_facility: Arellano-Harrison Medical Center reporter_type: Nurse notes: Situation side mouth. Peace subject analysis somebody apply moment interview. Note project animal live citizen which science. Never fast somebody realize bit radio gas identify.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-551 Date of Submission: 2024-11-02 This report was submitted by a Patient from Patterson Inc Medical Center concerning patient ANON-PX-8015. The subject is an adult male with a significant medical history including migraines, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Gabapentin (Anticonvulsant) administered via the Subcutaneous route at a dosage of 51mg, initiated on 2024-10-01 for Neuropathic pain and discontinued on 2024-10-24. On approximately 2024-10-13, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Dizziness, Anaphylaxis. The Diarrhea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed tree and advised phone. The current patient status regarding this symptom is 'Not Recovered'. The Dizziness was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Anaphylaxis was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: End north ability phone. All both author base. Different history instead political teach lot.</data>	report_id: ADR-2024-551 report_date: '2024-11-02' patient_details: patient_id: ANON-PX-8015 gender: Male relevant_history: - migraines - asthma suspected_drugs: - drug_name: Gabapentin dosage: 51mg route_of_administration: Subcutaneous start_date: '2024-10-01' indication_for_use: Neuropathic pain drug_class: Anticonvulsant end_date: '2024-10-24' adverse_reactions: - symptom_name: Diarrhea onset_date: '2024-10-13' severity: Mild outcome: Not Recovered intervention_required: true intervention_details: Prescribed tree and advised phone. - symptom_name: Dizziness onset_date: '2024-10-13' severity: Life-threatening outcome: Recovering intervention_required: false - symptom_name: Anaphylaxis onset_date: '2024-10-13' severity: Life-threatening outcome: Recovered intervention_required: false causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Rechallenge not performed reporting_facility: Patterson Inc Medical Center reporter_type: Patient notes: End north ability phone. All both author base. Different history instead political teach lot.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-827 Date of Submission: 2024-10-29 This report was submitted by a Other Healthcare Professional from Ford-Johnson Medical Center concerning patient ANON-PX-5956. The subject is a 20-year-old female with a significant medical history including type 2 diabetes, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Amoxicillin administered via the Subcutaneous route at a dosage of 230mg, initiated on 2024-09-12 for Bacterial infection and discontinued on 2024-10-22; Lisinopril administered via the Topical route at a dosage of 251mg, initiated on 2024-09-12 for Hypertension and discontinued on 2024-10-22. On approximately 2024-10-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Headache. The Maculopapular Rash was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed usually and advised task. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed their and advised region. The current patient status regarding this symptom is 'Not Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. </data>	report_id: ADR-2024-827 report_date: '2024-10-29' patient_details: patient_id: ANON-PX-5956 gender: Female relevant_history: - type 2 diabetes - chronic kidney disease age_at_reaction: 20 suspected_drugs: - drug_name: Amoxicillin dosage: 230mg route_of_administration: Subcutaneous start_date: '2024-09-12' indication_for_use: Bacterial infection end_date: '2024-10-22' - drug_name: Lisinopril dosage: 251mg route_of_administration: Topical start_date: '2024-09-12' indication_for_use: Hypertension end_date: '2024-10-22' adverse_reactions: - symptom_name: Maculopapular Rash onset_date: '2024-10-18' severity: Life-threatening outcome: Recovered intervention_required: true intervention_details: Prescribed usually and advised task. - symptom_name: Headache onset_date: '2024-10-18' severity: Life-threatening outcome: Not Recovered intervention_required: true intervention_details: Prescribed their and advised region. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Not applicable reporting_facility: Ford-Johnson Medical Center reporter_type: Other Healthcare Professional
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-404 Date of Submission: 2025-04-30 This report was submitted by a Patient from Davis-Williams Medical Center concerning patient ANON-PX-6714. The subject is an adult male with a significant medical history including chronic kidney disease, asthma, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Subcutaneous route at a dosage of 73mg, initiated on 2025-03-07 for Hypothyroidism and discontinued on 2025-04-29; Ibuprofen (NSAID) administered via the Intravenous route at a dosage of 473mg, initiated on 2025-03-07 for Pain and inflammation and discontinued on 2025-04-29. On approximately 2025-04-26, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Pruritus, Angioedema, Maculopapular Rash. The Stevens-Johnson syndrome was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Pruritus was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed mean and advised close. The current patient status regarding this symptom is 'Recovering'. The Angioedema was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Maculopapular Rash was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 1 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Treat tend rock same two skill Congress. Affect view police service several short police. Anyone similar indicate throw man sing.</data>	report_id: ADR-2025-404 report_date: '2025-04-30' patient_details: patient_id: ANON-PX-6714 gender: Male relevant_history: - chronic kidney disease - asthma - hypertension suspected_drugs: - drug_name: Levothyroxine dosage: 73mg route_of_administration: Subcutaneous start_date: '2025-03-07' indication_for_use: Hypothyroidism drug_class: Thyroid hormone end_date: '2025-04-29' - drug_name: Ibuprofen dosage: 473mg route_of_administration: Intravenous start_date: '2025-03-07' indication_for_use: Pain and inflammation drug_class: NSAID end_date: '2025-04-29' adverse_reactions: - symptom_name: Stevens-Johnson syndrome onset_date: '2025-04-26' severity: Mild outcome: Recovering intervention_required: true - symptom_name: Pruritus onset_date: '2025-04-26' severity: Moderate outcome: Recovering intervention_required: true intervention_details: Prescribed mean and advised close. - symptom_name: Angioedema onset_date: '2025-04-26' severity: Severe outcome: Unknown intervention_required: false - symptom_name: Maculopapular Rash onset_date: '2025-04-26' severity: Severe outcome: Unknown intervention_required: false causality_assessment: assessment_conclusion: Possible dechallenge_rechallenge: Positive rechallenge naranjo_score: 1 reporting_facility: Davis-Williams Medical Center reporter_type: Patient notes: Treat tend rock same two skill Congress. Affect view police service several short police. Anyone similar indicate throw man sing.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2025-296 Date of Submission: 2025-04-28 This report was submitted by a Nurse from Mayer Inc Medical Center concerning patient ANON-PX-8040. The subject is a 79-year-old male with a significant medical history including chronic kidney disease, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Atorvastatin administered via the Intramuscular route at a dosage of 388mg, initiated on 2025-03-08 for Hypercholesterolemia with the course ongoing; Levothyroxine administered via the Oral route at a dosage of 383mg, initiated on 2025-03-08 for Hypothyroidism with the course ongoing. On approximately 2025-04-16, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Somnolence, Hepatotoxicity. The Angioedema was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed prepare and advised environment. The current patient status regarding this symptom is 'Not Recovered'. The Somnolence was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Hepatotoxicity was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed money and advised while. The current patient status regarding this symptom is 'Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: For avoid news describe. Woman do conference people chair. All style wrong trial know couple.</data>	report_id: ADR-2025-296 report_date: '2025-04-28' patient_details: patient_id: ANON-PX-8040 gender: Male relevant_history: - chronic kidney disease - coronary artery disease age_at_reaction: 79 suspected_drugs: - drug_name: Atorvastatin dosage: 388mg route_of_administration: Intramuscular start_date: '2025-03-08' indication_for_use: Hypercholesterolemia - drug_name: Levothyroxine dosage: 383mg route_of_administration: Oral start_date: '2025-03-08' indication_for_use: Hypothyroidism adverse_reactions: - symptom_name: Angioedema onset_date: '2025-04-16' severity: Moderate outcome: Not Recovered intervention_required: true intervention_details: Prescribed prepare and advised environment. - symptom_name: Somnolence onset_date: '2025-04-16' severity: Moderate outcome: Recovering intervention_required: true - symptom_name: Hepatotoxicity onset_date: '2025-04-16' severity: Moderate outcome: Recovered intervention_required: true intervention_details: Prescribed money and advised while. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive dechallenge naranjo_score: 7 reporting_facility: Mayer Inc Medical Center reporter_type: Nurse notes: For avoid news describe. Woman do conference people chair. All style wrong trial know couple.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-343 Date of Submission: 2024-12-05 This report was submitted by a Nurse from Baldwin-Cook Medical Center concerning patient ANON-PX-6067. The subject is a 89-year-old other with a significant medical history including atrial fibrillation, anxiety, asthma, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Subcutaneous route at a dosage of 480mg, initiated on 2024-09-28 for Hypothyroidism with the course ongoing; Ibuprofen administered via the Intravenous route at a dosage of 432mg, initiated on 2024-09-28 for Pain and inflammation with the course ongoing. On approximately 2024-10-27, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Somnolence, Nausea. The Stevens-Johnson syndrome was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed other and advised need. The current patient status regarding this symptom is 'Recovering'. The Somnolence was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Nausea was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed year and advised win. The current patient status regarding this symptom is 'Not Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 1 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Out risk out issue base. Here increase hour while these hit decade.</data>	report_id: ADR-2024-343 report_date: '2024-12-05' patient_details: patient_id: ANON-PX-6067 gender: Other relevant_history: - atrial fibrillation - anxiety - asthma - osteoarthritis age_at_reaction: 89 suspected_drugs: - drug_name: Levothyroxine dosage: 480mg route_of_administration: Subcutaneous start_date: '2024-09-28' indication_for_use: Hypothyroidism drug_class: Thyroid hormone - drug_name: Ibuprofen dosage: 432mg route_of_administration: Intravenous start_date: '2024-09-28' indication_for_use: Pain and inflammation adverse_reactions: - symptom_name: Stevens-Johnson syndrome onset_date: '2024-10-27' severity: Severe outcome: Recovering intervention_required: true intervention_details: Prescribed other and advised need. - symptom_name: Somnolence onset_date: '2024-10-27' severity: Severe outcome: Unknown intervention_required: false - symptom_name: Nausea onset_date: '2024-10-27' severity: Life-threatening outcome: Not Recovered intervention_required: true intervention_details: Prescribed year and advised win. causality_assessment: assessment_conclusion: Possible dechallenge_rechallenge: Positive dechallenge naranjo_score: 1 reporting_facility: Baldwin-Cook Medical Center reporter_type: Nurse notes: Out risk out issue base. Here increase hour while these hit decade.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-747 Date of Submission: 2024-11-15 This report was submitted by a Pharmacist from Anderson-Miller Medical Center concerning patient ANON-PX-5579. The subject is a 22-year-old female with a significant medical history including anxiety, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Intravenous route at a dosage of 28mg, initiated on 2024-09-18 for Pain and inflammation with the course ongoing; Warfarin administered via the Subcutaneous route at a dosage of 426mg, initiated on 2024-09-18 for Thromboembolism prevention with the course ongoing. On approximately 2024-10-12, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Angioedema, Diarrhea, Dizziness. The Nausea was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Angioedema was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed spend and advised since. The current patient status regarding this symptom is 'Unknown'. The Dizziness was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed guess and advised country. The current patient status regarding this symptom is 'Recovering'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Add improve marriage. Woman piece management exist foot.</data>	report_id: ADR-2024-747 report_date: '2024-11-15' patient_details: patient_id: ANON-PX-5579 gender: Female relevant_history: - anxiety - atrial fibrillation age_at_reaction: 22 suspected_drugs: - drug_name: Ibuprofen dosage: 28mg route_of_administration: Intravenous start_date: '2024-09-18' indication_for_use: Pain and inflammation drug_class: NSAID - drug_name: Warfarin dosage: 426mg route_of_administration: Subcutaneous start_date: '2024-09-18' indication_for_use: Thromboembolism prevention adverse_reactions: - symptom_name: Nausea onset_date: '2024-10-12' severity: Moderate outcome: Recovered intervention_required: false - symptom_name: Angioedema onset_date: '2024-10-12' severity: Mild outcome: Recovering intervention_required: true - symptom_name: Diarrhea onset_date: '2024-10-12' severity: Moderate outcome: Unknown intervention_required: true intervention_details: Prescribed spend and advised since. - symptom_name: Dizziness onset_date: '2024-10-12' severity: Severe outcome: Recovering intervention_required: true intervention_details: Prescribed guess and advised country. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive rechallenge naranjo_score: 7 reporting_facility: Anderson-Miller Medical Center reporter_type: Pharmacist notes: Add improve marriage. Woman piece management exist foot.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-867 Date of Submission: 2024-11-13 This report was submitted by a Nurse from Rogers-Clay Medical Center concerning patient ANON-PX-5926. The subject is a 77-year-old male with a significant medical history including hypertension, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Metformin administered via the Intravenous route at a dosage of 88mg, initiated on 2024-09-04 for Type 2 diabetes and discontinued on 2024-10-24. On approximately 2024-09-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Nausea, Anaphylaxis. The Maculopapular Rash was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Nausea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Anaphylaxis was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 2 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. Reporter's Narrative Summary: Laugh none life rise general material enjoy. Throughout community return knowledge evidence possible specific.</data>	report_id: ADR-2024-867 report_date: '2024-11-13' patient_details: patient_id: ANON-PX-5926 gender: Male relevant_history: - hypertension - type 2 diabetes age_at_reaction: 77 suspected_drugs: - drug_name: Metformin dosage: 88mg route_of_administration: Intravenous start_date: '2024-09-04' indication_for_use: Type 2 diabetes end_date: '2024-10-24' adverse_reactions: - symptom_name: Maculopapular Rash onset_date: '2024-09-18' severity: Moderate outcome: Recovering intervention_required: false - symptom_name: Nausea onset_date: '2024-09-18' severity: Mild outcome: Unknown intervention_required: false - symptom_name: Anaphylaxis onset_date: '2024-09-18' severity: Mild outcome: Unknown intervention_required: false causality_assessment: assessment_conclusion: Possible dechallenge_rechallenge: Positive rechallenge naranjo_score: 2 reporting_facility: Rogers-Clay Medical Center reporter_type: Nurse notes: Laugh none life rise general material enjoy. Throughout community return knowledge evidence possible specific.
<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL Report Identifier: ADR-2024-477 Date of Submission: 2024-10-19 This report was submitted by a Physician from Nguyen, Romero and Ramos Medical Center concerning patient ANON-PX-4330. The subject is a 40-year-old male with a significant medical history including hypertension, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Topical route at a dosage of 144mg, initiated on 2024-08-26 for Pain and inflammation with the course ongoing; Sertraline administered via the Topical route at a dosage of 162mg, initiated on 2024-08-26 for Major depressive disorder with the course ongoing. On approximately 2024-09-13, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Headache, Diarrhea, Pruritus. The Dizziness was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed keep and advised always. The current patient status regarding this symptom is 'Unknown'. The Headache was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Diarrhea was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Pruritus was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed case and advised his. The current patient status regarding this symptom is 'Recovered'. CAUSALITY ASSESSMENT: An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. </data>	report_id: ADR-2024-477 report_date: '2024-10-19' patient_details: patient_id: ANON-PX-4330 gender: Male relevant_history: - hypertension - chronic kidney disease age_at_reaction: 40 suspected_drugs: - drug_name: Ibuprofen dosage: 144mg route_of_administration: Topical start_date: '2024-08-26' indication_for_use: Pain and inflammation drug_class: NSAID - drug_name: Sertraline dosage: 162mg route_of_administration: Topical start_date: '2024-08-26' indication_for_use: Major depressive disorder adverse_reactions: - symptom_name: Dizziness onset_date: '2024-09-13' severity: Severe outcome: Unknown intervention_required: true intervention_details: Prescribed keep and advised always. - symptom_name: Headache onset_date: '2024-09-13' severity: Life-threatening outcome: Fatal intervention_required: false - symptom_name: Diarrhea onset_date: '2024-09-13' severity: Moderate outcome: Fatal intervention_required: true - symptom_name: Pruritus onset_date: '2024-09-13' severity: Moderate outcome: Recovered intervention_required: true intervention_details: Prescribed case and advised his. causality_assessment: assessment_conclusion: Probable dechallenge_rechallenge: Positive dechallenge naranjo_score: 5 reporting_facility: Nguyen, Romero and Ramos Medical Center reporter_type: Physician