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Aug 20

Multimodal Data Integration for Oncology in the Era of Deep Neural Networks: A Review

Cancer has relational information residing at varying scales, modalities, and resolutions of the acquired data, such as radiology, pathology, genomics, proteomics, and clinical records. Integrating diverse data types can improve the accuracy and reliability of cancer diagnosis and treatment. There can be disease-related information that is too subtle for humans or existing technological tools to discern visually. Traditional methods typically focus on partial or unimodal information about biological systems at individual scales and fail to encapsulate the complete spectrum of the heterogeneous nature of data. Deep neural networks have facilitated the development of sophisticated multimodal data fusion approaches that can extract and integrate relevant information from multiple sources. Recent deep learning frameworks such as Graph Neural Networks (GNNs) and Transformers have shown remarkable success in multimodal learning. This review article provides an in-depth analysis of the state-of-the-art in GNNs and Transformers for multimodal data fusion in oncology settings, highlighting notable research studies and their findings. We also discuss the foundations of multimodal learning, inherent challenges, and opportunities for integrative learning in oncology. By examining the current state and potential future developments of multimodal data integration in oncology, we aim to demonstrate the promising role that multimodal neural networks can play in cancer prevention, early detection, and treatment through informed oncology practices in personalized settings.

PETGEN: Personalized Text Generation Attack on Deep Sequence Embedding-based Classification Models

What should a malicious user write next to fool a detection model? Identifying malicious users is critical to ensure the safety and integrity of internet platforms. Several deep learning-based detection models have been created. However, malicious users can evade deep detection models by manipulating their behavior, rendering these models of little use. The vulnerability of such deep detection models against adversarial attacks is unknown. Here we create a novel adversarial attack model against deep user sequence embedding based classification models, which use the sequence of user posts to generate user embeddings and detect malicious users. In the attack, the adversary generates a new post to fool the classifier. We propose a novel end-to-end Personalized Text Generation Attack model, called PETGEN, that simultaneously reduces the efficacy of the detection model and generates posts that have several key desirable properties. Specifically, PETGEN generates posts that are personalized to the user's writing style, have knowledge about a given target context, are aware of the user's historical posts on the target context, and encapsulate the user's recent topical interests. We conduct extensive experiments on two real-world datasets (Yelp and Wikipedia, both with ground-truth of malicious users) to show that PETGEN significantly reduces the performance of popular deep user sequence embedding-based classification models. PETGEN outperforms five attack baselines in terms of text quality and attack efficacy in both white-box and black-box classifier settings. Overall, this work paves the path towards the next generation of adversary-aware sequence classification models.

Do LLMs Recognize Your Preferences? Evaluating Personalized Preference Following in LLMs

Large Language Models (LLMs) are increasingly used as chatbots, yet their ability to personalize responses to user preferences remains limited. We introduce PrefEval, a benchmark for evaluating LLMs' ability to infer, memorize and adhere to user preferences in a long-context conversational setting. PrefEval comprises 3,000 manually curated user preference and query pairs spanning 20 topics. PrefEval contains user personalization or preference information in both explicit and implicit forms, and evaluates LLM performance using a generation and a classification task. With PrefEval, we evaluated the aforementioned preference following capabilities of 10 open-source and proprietary LLMs in multi-session conversations with varying context lengths up to 100k tokens. We benchmark with various prompting, iterative feedback, and retrieval-augmented generation methods. Our benchmarking effort reveals that state-of-the-art LLMs face significant challenges in proactively following users' preferences during conversations. In particular, in zero-shot settings, preference following accuracy falls below 10% at merely 10 turns (~3k tokens) across most evaluated models. Even with advanced prompting and retrieval methods, preference following still deteriorates in long-context conversations. Furthermore, we show that fine-tuning on PrefEval significantly improves performance. We believe PrefEval serves as a valuable resource for measuring, understanding, and enhancing LLMs' preference following abilities, paving the way for personalized conversational agents. Our code and dataset are available at https://prefeval.github.io/.

When StyleGAN Meets Stable Diffusion: a $\mathscr{W}_+$ Adapter for Personalized Image Generation

Text-to-image diffusion models have remarkably excelled in producing diverse, high-quality, and photo-realistic images. This advancement has spurred a growing interest in incorporating specific identities into generated content. Most current methods employ an inversion approach to embed a target visual concept into the text embedding space using a single reference image. However, the newly synthesized faces either closely resemble the reference image in terms of facial attributes, such as expression, or exhibit a reduced capacity for identity preservation. Text descriptions intended to guide the facial attributes of the synthesized face may fall short, owing to the intricate entanglement of identity information with identity-irrelevant facial attributes derived from the reference image. To address these issues, we present the novel use of the extended StyleGAN embedding space W_+, to achieve enhanced identity preservation and disentanglement for diffusion models. By aligning this semantically meaningful human face latent space with text-to-image diffusion models, we succeed in maintaining high fidelity in identity preservation, coupled with the capacity for semantic editing. Additionally, we propose new training objectives to balance the influences of both prompt and identity conditions, ensuring that the identity-irrelevant background remains unaffected during facial attribute modifications. Extensive experiments reveal that our method adeptly generates personalized text-to-image outputs that are not only compatible with prompt descriptions but also amenable to common StyleGAN editing directions in diverse settings. Our source code will be available at https://github.com/csxmli2016/w-plus-adapter.

Promoting AI Literacy in Higher Education: Evaluating the IEC-V1 Chatbot for Personalized Learning and Educational Equity

The unequal distribution of educational opportunities carries the risk of having a long-term negative impact on general social peace, a country's economy and basic democratic structures. In contrast to this observable development is the rapid technological progress in the field of artificial intelligence (AI). Progress makes it possible to solve various problems in the field of education as well. In order to effectively exploit the advantages that arise from the use of AI, prospective teacher training students need appropriate AI skills, which must already be taught during their studies. In a first step, the added value of this technology will be demonstrated using a concrete example. This article is therefore about conducting an exploratory pilot study to test the Individual Educational Chatbot (IEC-V1) prototype, in which the levels can be individually determined in order to generate appropriate answers depending on the requirements. The results show that this is an important function for prospective teachers, and that there is great interest in taking a closer look at this technology in order to be able to better support learners in the future. The data shows that experience has already been gained with chatbots, but that there is still room for improvement. It also shows that IEC-V1 is already working well. The knowledge gained will be used for the further development of the prototype to further improve the usability of the chatbot. Overall, it is shown that useful AI applications can be effectively integrated into learning situations even without proprietary systems and that important data protection requirements can be complied with.

Key-Locked Rank One Editing for Text-to-Image Personalization

Text-to-image models (T2I) offer a new level of flexibility by allowing users to guide the creative process through natural language. However, personalizing these models to align with user-provided visual concepts remains a challenging problem. The task of T2I personalization poses multiple hard challenges, such as maintaining high visual fidelity while allowing creative control, combining multiple personalized concepts in a single image, and keeping a small model size. We present Perfusion, a T2I personalization method that addresses these challenges using dynamic rank-1 updates to the underlying T2I model. Perfusion avoids overfitting by introducing a new mechanism that "locks" new concepts' cross-attention Keys to their superordinate category. Additionally, we develop a gated rank-1 approach that enables us to control the influence of a learned concept during inference time and to combine multiple concepts. This allows runtime-efficient balancing of visual-fidelity and textual-alignment with a single 100KB trained model, which is five orders of magnitude smaller than the current state of the art. Moreover, it can span different operating points across the Pareto front without additional training. Finally, we show that Perfusion outperforms strong baselines in both qualitative and quantitative terms. Importantly, key-locking leads to novel results compared to traditional approaches, allowing to portray personalized object interactions in unprecedented ways, even in one-shot settings.

Integrating Summarization and Retrieval for Enhanced Personalization via Large Language Models

Personalization, the ability to tailor a system to individual users, is an essential factor in user experience with natural language processing (NLP) systems. With the emergence of Large Language Models (LLMs), a key question is how to leverage these models to better personalize user experiences. To personalize a language model's output, a straightforward approach is to incorporate past user data into the language model prompt, but this approach can result in lengthy inputs exceeding limitations on input length and incurring latency and cost issues. Existing approaches tackle such challenges by selectively extracting relevant user data (i.e. selective retrieval) to construct a prompt for downstream tasks. However, retrieval-based methods are limited by potential information loss, lack of more profound user understanding, and cold-start challenges. To overcome these limitations, we propose a novel summary-augmented approach by extending retrieval-augmented personalization with task-aware user summaries generated by LLMs. The summaries can be generated and stored offline, enabling real-world systems with runtime constraints like voice assistants to leverage the power of LLMs. Experiments show our method with 75% less of retrieved user data is on-par or outperforms retrieval augmentation on most tasks in the LaMP personalization benchmark. We demonstrate that offline summarization via LLMs and runtime retrieval enables better performance for personalization on a range of tasks under practical constraints.

LLMs + Persona-Plug = Personalized LLMs

Personalization plays a critical role in numerous language tasks and applications, since users with the same requirements may prefer diverse outputs based on their individual interests. This has led to the development of various personalized approaches aimed at adapting large language models (LLMs) to generate customized outputs aligned with user preferences. Some of them involve fine-tuning a unique personalized LLM for each user, which is too expensive for widespread application. Alternative approaches introduce personalization information in a plug-and-play manner by retrieving the user's relevant historical texts as demonstrations. However, this retrieval-based strategy may break the continuity of the user history and fail to capture the user's overall styles and patterns, hence leading to sub-optimal performance. To address these challenges, we propose a novel personalized LLM model, . It constructs a user-specific embedding for each individual by modeling all her historical contexts through a lightweight plug-in user embedder module. By attaching this embedding to the task input, LLMs can better understand and capture user habits and preferences, thereby producing more personalized outputs without tuning their own parameters. Extensive experiments on various tasks in the language model personalization (LaMP) benchmark demonstrate that the proposed model significantly outperforms existing personalized LLM approaches.

Towards Unified Multi-Modal Personalization: Large Vision-Language Models for Generative Recommendation and Beyond

Developing a universal model that can effectively harness heterogeneous resources and respond to a wide range of personalized needs has been a longstanding community aspiration. Our daily choices, especially in domains like fashion and retail, are substantially shaped by multi-modal data, such as pictures and textual descriptions. These modalities not only offer intuitive guidance but also cater to personalized user preferences. However, the predominant personalization approaches mainly focus on the ID or text-based recommendation problem, failing to comprehend the information spanning various tasks or modalities. In this paper, our goal is to establish a Unified paradigm for Multi-modal Personalization systems (UniMP), which effectively leverages multi-modal data while eliminating the complexities associated with task- and modality-specific customization. We argue that the advancements in foundational generative modeling have provided the flexibility and effectiveness necessary to achieve the objective. In light of this, we develop a generic and extensible personalization generative framework, that can handle a wide range of personalized needs including item recommendation, product search, preference prediction, explanation generation, and further user-guided image generation. Our methodology enhances the capabilities of foundational language models for personalized tasks by seamlessly ingesting interleaved cross-modal user history information, ensuring a more precise and customized experience for users. To train and evaluate the proposed multi-modal personalized tasks, we also introduce a novel and comprehensive benchmark covering a variety of user requirements. Our experiments on the real-world benchmark showcase the model's potential, outperforming competitive methods specialized for each task.

Personalized Image Generation with Deep Generative Models: A Decade Survey

Recent advancements in generative models have significantly facilitated the development of personalized content creation. Given a small set of images with user-specific concept, personalized image generation allows to create images that incorporate the specified concept and adhere to provided text descriptions. Due to its wide applications in content creation, significant effort has been devoted to this field in recent years. Nonetheless, the technologies used for personalization have evolved alongside the development of generative models, with their distinct and interrelated components. In this survey, we present a comprehensive review of generalized personalized image generation across various generative models, including traditional GANs, contemporary text-to-image diffusion models, and emerging multi-model autoregressive models. We first define a unified framework that standardizes the personalization process across different generative models, encompassing three key components, i.e., inversion spaces, inversion methods, and personalization schemes. This unified framework offers a structured approach to dissecting and comparing personalization techniques across different generative architectures. Building upon this unified framework, we further provide an in-depth analysis of personalization techniques within each generative model, highlighting their unique contributions and innovations. Through comparative analysis, this survey elucidates the current landscape of personalized image generation, identifying commonalities and distinguishing features among existing methods. Finally, we discuss the open challenges in the field and propose potential directions for future research. We keep tracing related works at https://github.com/csyxwei/Awesome-Personalized-Image-Generation.

Personalized Image Generation with Large Multimodal Models

Personalized content filtering, such as recommender systems, has become a critical infrastructure to alleviate information overload. However, these systems merely filter existing content and are constrained by its limited diversity, making it difficult to meet users' varied content needs. To address this limitation, personalized content generation has emerged as a promising direction with broad applications. Nevertheless, most existing research focuses on personalized text generation, with relatively little attention given to personalized image generation. The limited work in personalized image generation faces challenges in accurately capturing users' visual preferences and needs from noisy user-interacted images and complex multimodal instructions. Worse still, there is a lack of supervised data for training personalized image generation models. To overcome the challenges, we propose a Personalized Image Generation Framework named Pigeon, which adopts exceptional large multimodal models with three dedicated modules to capture users' visual preferences and needs from noisy user history and multimodal instructions. To alleviate the data scarcity, we introduce a two-stage preference alignment scheme, comprising masked preference reconstruction and pairwise preference alignment, to align Pigeon with the personalized image generation task. We apply Pigeon to personalized sticker and movie poster generation, where extensive quantitative results and human evaluation highlight its superiority over various generative baselines.

When Large Language Models Meet Personalization: Perspectives of Challenges and Opportunities

The advent of large language models marks a revolutionary breakthrough in artificial intelligence. With the unprecedented scale of training and model parameters, the capability of large language models has been dramatically improved, leading to human-like performances in understanding, language synthesizing, and common-sense reasoning, etc. Such a major leap-forward in general AI capacity will change the pattern of how personalization is conducted. For one thing, it will reform the way of interaction between humans and personalization systems. Instead of being a passive medium of information filtering, large language models present the foundation for active user engagement. On top of such a new foundation, user requests can be proactively explored, and user's required information can be delivered in a natural and explainable way. For another thing, it will also considerably expand the scope of personalization, making it grow from the sole function of collecting personalized information to the compound function of providing personalized services. By leveraging large language models as general-purpose interface, the personalization systems may compile user requests into plans, calls the functions of external tools to execute the plans, and integrate the tools' outputs to complete the end-to-end personalization tasks. Today, large language models are still being developed, whereas the application in personalization is largely unexplored. Therefore, we consider it to be the right time to review the challenges in personalization and the opportunities to address them with LLMs. In particular, we dedicate this perspective paper to the discussion of the following aspects: the development and challenges for the existing personalization system, the newly emerged capabilities of large language models, and the potential ways of making use of large language models for personalization.

NextQuill: Causal Preference Modeling for Enhancing LLM Personalization

Personalizing large language models (LLMs) for individual users has become increasingly important as they are progressively integrated into real-world applications to support users' daily lives. However, existing personalization approaches often fail to distinguish which components of model predictions and training data truly reflect user preferences, leading to superficial personalization alignment. In this paper, we introduce NextQuill, a novel LLM personalization alignment framework grounded in causal preference modeling. We approach personalization from a causal perspective, treating both model predictions and ground-truth data generation as outcomes influenced by user preferences, along with other factors. We define the true preference effect as the causal impact of user history (which reflects preferences) on each token prediction or data generation instance, estimated through causal intervention techniques. Building on this insight, NextQuill introduces two complementary alignment strategies: (1) aligning model-internal causal preference effects on predictions with those reflected in ground-truth data, rather than indiscriminately fitting predictions, and (2) focusing on fitting preference-bearing tokens identified via ground-truth data preference effects, rather than treating all tokens uniformly. By integrating these strategies, NextQuill shifts the alignment process toward learning from causal preference effects, facilitating more effective and personalized adaptation. Experiments across multiple personalization benchmarks demonstrate that NextQuill significantly improves personalization quality, offering a principled, causal foundation for LLM personalization. Our codes are available on https://github.com/juntaoyou/NextQuill.

UNICON: A unified framework for behavior-based consumer segmentation in e-commerce

Data-driven personalization is a key practice in fashion e-commerce, improving the way businesses serve their consumers needs with more relevant content. While hyper-personalization offers highly targeted experiences to each consumer, it requires a significant amount of private data to create an individualized journey. To alleviate this, group-based personalization provides a moderate level of personalization built on broader common preferences of a consumer segment, while still being able to personalize the results. We introduce UNICON, a unified deep learning consumer segmentation framework that leverages rich consumer behavior data to learn long-term latent representations and utilizes them to extract two pivotal types of segmentation catering various personalization use-cases: lookalike, expanding a predefined target seed segment with consumers of similar behavior, and data-driven, revealing non-obvious consumer segments with similar affinities. We demonstrate through extensive experimentation our framework effectiveness in fashion to identify lookalike Designer audience and data-driven style segments. Furthermore, we present experiments that showcase how segment information can be incorporated in a hybrid recommender system combining hyper and group-based personalization to exploit the advantages of both alternatives and provide improvements on consumer experience.

PersonaBench: Evaluating AI Models on Understanding Personal Information through Accessing (Synthetic) Private User Data

Personalization is critical in AI assistants, particularly in the context of private AI models that work with individual users. A key scenario in this domain involves enabling AI models to access and interpret a user's private data (e.g., conversation history, user-AI interactions, app usage) to understand personal details such as biographical information, preferences, and social connections. However, due to the sensitive nature of such data, there are no publicly available datasets that allow us to assess an AI model's ability to understand users through direct access to personal information. To address this gap, we introduce a synthetic data generation pipeline that creates diverse, realistic user profiles and private documents simulating human activities. Leveraging this synthetic data, we present PersonaBench, a benchmark designed to evaluate AI models' performance in understanding personal information derived from simulated private user data. We evaluate Retrieval-Augmented Generation (RAG) pipelines using questions directly related to a user's personal information, supported by the relevant private documents provided to the models. Our results reveal that current retrieval-augmented AI models struggle to answer private questions by extracting personal information from user documents, highlighting the need for improved methodologies to enhance personalization capabilities in AI.

Big-data-driven and AI-based framework to enable personalization in wireless networks

Current communication networks use design methodologies that prevent the realization of maximum network efficiency. In the first place, while users' perception of satisfactory service diverges widely, current networks are designed to be a "universal fit," where they are generally over-engineered to deliver services appealing to all types of users. Also, current networks lack user-level data cognitive intelligence that would enable fast personalized network decisions and actions through automation. Thus, in this article, we propose the utilization of AI, big data analytics, and real-time non-intrusive user feedback in order to enable the personalization of wireless networks. Based on each user's actual QoS requirements and context, a multi-objective formulation enables the network to micro-manage and optimize the provided QoS and user satisfaction levels simultaneously. Moreover, in order to enable user feedback tracking and measurement, we propose a user satisfaction model based on the zone of tolerance concept. Furthermore, we propose a big-data-driven and AI-based personalization framework to integrate personalization into wireless networks. Finally, we implement a personalized network prototype to demonstrate the proposed personalization concept and its potential benefits through a case study. The case study shows how personalization can be realized to enable the efficient optimization of network resources such that certain requirement levels of user satisfaction and revenue in the form of saved resources are achieved.

FSPO: Few-Shot Preference Optimization of Synthetic Preference Data in LLMs Elicits Effective Personalization to Real Users

Effective personalization of LLMs is critical for a broad range of user-interfacing applications such as virtual assistants and content curation. Inspired by the strong in-context learning capabilities of LLMs, we propose Few-Shot Preference Optimization (FSPO), which reframes reward modeling as a meta-learning problem. Under this framework, an LLM learns to quickly adapt to a user via a few labeled preferences from that user, constructing a personalized reward function for them. Additionally, since real-world preference data is scarce and challenging to collect at scale, we propose careful design choices to construct synthetic preference datasets for personalization, generating over 1M synthetic personalized preferences using publicly available LLMs. In particular, to successfully transfer from synthetic data to real users, we find it crucial for the data to exhibit both high diversity and coherent, self-consistent structure. We evaluate FSPO on personalized open-ended generation for up to 1,500 synthetic users across across three domains: movie reviews, pedagogical adaptation based on educational background, and general question answering, along with a controlled human study. Overall, FSPO achieves an 87% Alpaca Eval winrate on average in generating responses that are personalized to synthetic users and a 72% winrate with real human users in open-ended question answering.

ULMRec: User-centric Large Language Model for Sequential Recommendation

Recent advances in Large Language Models (LLMs) have demonstrated promising performance in sequential recommendation tasks, leveraging their superior language understanding capabilities. However, existing LLM-based recommendation approaches predominantly focus on modeling item-level co-occurrence patterns while failing to adequately capture user-level personalized preferences. This is problematic since even users who display similar behavioral patterns (e.g., clicking or purchasing similar items) may have fundamentally different underlying interests. To alleviate this problem, in this paper, we propose ULMRec, a framework that effectively integrates user personalized preferences into LLMs for sequential recommendation. Considering there has the semantic gap between item IDs and LLMs, we replace item IDs with their corresponding titles in user historical behaviors, enabling the model to capture the item semantics. For integrating the user personalized preference, we design two key components: (1) user indexing: a personalized user indexing mechanism that leverages vector quantization on user reviews and user IDs to generate meaningful and unique user representations, and (2) alignment tuning: an alignment-based tuning stage that employs comprehensive preference alignment tasks to enhance the model's capability in capturing personalized information. Through this design, ULMRec achieves deep integration of language semantics with user personalized preferences, facilitating effective adaptation to recommendation. Extensive experiments on two public datasets demonstrate that ULMRec significantly outperforms existing methods, validating the effectiveness of our approach.

On the Conversational Persuasiveness of Large Language Models: A Randomized Controlled Trial

The development and popularization of large language models (LLMs) have raised concerns that they will be used to create tailor-made, convincing arguments to push false or misleading narratives online. Early work has found that language models can generate content perceived as at least on par and often more persuasive than human-written messages. However, there is still limited knowledge about LLMs' persuasive capabilities in direct conversations with human counterparts and how personalization can improve their performance. In this pre-registered study, we analyze the effect of AI-driven persuasion in a controlled, harmless setting. We create a web-based platform where participants engage in short, multiple-round debates with a live opponent. Each participant is randomly assigned to one of four treatment conditions, corresponding to a two-by-two factorial design: (1) Games are either played between two humans or between a human and an LLM; (2) Personalization might or might not be enabled, granting one of the two players access to basic sociodemographic information about their opponent. We found that participants who debated GPT-4 with access to their personal information had 81.7% (p < 0.01; N=820 unique participants) higher odds of increased agreement with their opponents compared to participants who debated humans. Without personalization, GPT-4 still outperforms humans, but the effect is lower and statistically non-significant (p=0.31). Overall, our results suggest that concerns around personalization are meaningful and have important implications for the governance of social media and the design of new online environments.

Recommendation as Language Processing (RLP): A Unified Pretrain, Personalized Prompt & Predict Paradigm (P5)

For a long time, different recommendation tasks typically require designing task-specific architectures and training objectives. As a result, it is hard to transfer the learned knowledge and representations from one task to another, thus restricting the generalization ability of existing recommendation approaches, e.g., a sequential recommendation model can hardly be applied or transferred to a review generation method. To deal with such issues, considering that language can describe almost anything and language grounding is a powerful medium to represent various problems or tasks, we present a flexible and unified text-to-text paradigm called "Pretrain, Personalized Prompt, and Predict Paradigm" (P5) for recommendation, which unifies various recommendation tasks in a shared framework. In P5, all data such as user-item interactions, user descriptions, item metadata, and user reviews are converted to a common format -- natural language sequences. The rich information from natural language assists P5 to capture deeper semantics for personalization and recommendation. Specifically, P5 learns different tasks with the same language modeling objective during pretraining. Thus, it serves as the foundation model for various downstream recommendation tasks, allows easy integration with other modalities, and enables instruction-based recommendation based on prompts. P5 advances recommender systems from shallow model to deep model to big model, and will revolutionize the technical form of recommender systems towards universal recommendation engine. With adaptive personalized prompt for different users, P5 is able to make predictions in a zero-shot or few-shot manner and largely reduces the necessity for extensive fine-tuning. On several recommendation benchmarks, we conduct experiments to show the effectiveness of P5. We release the source code at https://github.com/jeykigung/P5.

PersonaFeedback: A Large-scale Human-annotated Benchmark For Personalization

With the rapid improvement in the general capabilities of LLMs, LLM personalization, i.e., how to build LLM systems that can generate personalized responses or services that are tailored to distinct user personas, has become an increasingly important research and engineering problem. However, unlike many new challenging benchmarks being released for evaluating the general/reasoning capabilities, the lack of high-quality benchmarks for evaluating LLM personalization greatly hinders progress in this field. To address this, we introduce PersonaFeedback, a new benchmark that directly evaluates LLMs' ability to provide personalized responses given pre-defined user personas and queries. Unlike existing benchmarks that require models to infer implicit user personas from historical interactions, PersonaFeedback decouples persona inference from personalization, focusing on evaluating the model's ability to generate responses tailored to explicit personas. PersonaFeedback consists of 8298 human-annotated test cases, which are categorized into easy, medium, and hard tiers based on the contextual complexity of the user personas and the difficulty in distinguishing subtle differences between two personalized responses. We conduct comprehensive evaluations across a wide range of models. The empirical results reveal that even state-of-the-art LLMs that can solve complex real-world reasoning tasks could fall short on the hard tier of PersonaFeedback where even human evaluators may find the distinctions challenging. Furthermore, we conduct an in-depth analysis of failure modes across various types of systems, demonstrating that the current retrieval-augmented framework should not be seen as a de facto solution for personalization tasks. All benchmark data, annotation protocols, and the evaluation pipeline will be publicly available to facilitate future research on LLM personalization.

Control of Medical Digital Twins with Artificial Neural Networks

The objective of personalized medicine is to tailor interventions to an individual patient's unique characteristics. A key technology for this purpose involves medical digital twins, computational models of human biology that can be personalized and dynamically updated to incorporate patient-specific data collected over time. Certain aspects of human biology, such as the immune system, are not easily captured with physics-based models, such as differential equations. Instead, they are often multi-scale, stochastic, and hybrid. This poses a challenge to existing model-based control and optimization approaches that cannot be readily applied to such models. Recent advances in automatic differentiation and neural-network control methods hold promise in addressing complex control problems. However, the application of these approaches to biomedical systems is still in its early stages. This work introduces dynamics-informed neural-network controllers as an alternative approach to control of medical digital twins. As a first use case for this method, the focus is on agent-based models, a versatile and increasingly common modeling platform in biomedicine. The effectiveness of the proposed neural-network control method is illustrated and benchmarked against other methods with two widely-used agent-based model types. The relevance of the method introduced here extends beyond medical digital twins to other complex dynamical systems.

Gen4Gen: Generative Data Pipeline for Generative Multi-Concept Composition

Recent text-to-image diffusion models are able to learn and synthesize images containing novel, personalized concepts (e.g., their own pets or specific items) with just a few examples for training. This paper tackles two interconnected issues within this realm of personalizing text-to-image diffusion models. First, current personalization techniques fail to reliably extend to multiple concepts -- we hypothesize this to be due to the mismatch between complex scenes and simple text descriptions in the pre-training dataset (e.g., LAION). Second, given an image containing multiple personalized concepts, there lacks a holistic metric that evaluates performance on not just the degree of resemblance of personalized concepts, but also whether all concepts are present in the image and whether the image accurately reflects the overall text description. To address these issues, we introduce Gen4Gen, a semi-automated dataset creation pipeline utilizing generative models to combine personalized concepts into complex compositions along with text-descriptions. Using this, we create a dataset called MyCanvas, that can be used to benchmark the task of multi-concept personalization. In addition, we design a comprehensive metric comprising two scores (CP-CLIP and TI-CLIP) for better quantifying the performance of multi-concept, personalized text-to-image diffusion methods. We provide a simple baseline built on top of Custom Diffusion with empirical prompting strategies for future researchers to evaluate on MyCanvas. We show that by improving data quality and prompting strategies, we can significantly increase multi-concept personalized image generation quality, without requiring any modifications to model architecture or training algorithms.

One Chatbot Per Person: Creating Personalized Chatbots based on Implicit User Profiles

Personalized chatbots focus on endowing chatbots with a consistent personality to behave like real users, give more informative responses, and further act as personal assistants. Existing personalized approaches tried to incorporate several text descriptions as explicit user profiles. However, the acquisition of such explicit profiles is expensive and time-consuming, thus being impractical for large-scale real-world applications. Moreover, the restricted predefined profile neglects the language behavior of a real user and cannot be automatically updated together with the change of user interests. In this paper, we propose to learn implicit user profiles automatically from large-scale user dialogue history for building personalized chatbots. Specifically, leveraging the benefits of Transformer on language understanding, we train a personalized language model to construct a general user profile from the user's historical responses. To highlight the relevant historical responses to the input post, we further establish a key-value memory network of historical post-response pairs, and build a dynamic post-aware user profile. The dynamic profile mainly describes what and how the user has responded to similar posts in history. To explicitly utilize users' frequently used words, we design a personalized decoder to fuse two decoding strategies, including generating a word from the generic vocabulary and copying one word from the user's personalized vocabulary. Experiments on two real-world datasets show the significant improvement of our model compared with existing methods. Our code is available at https://github.com/zhengyima/DHAP

Improved Personalized Headline Generation via Denoising Fake Interests from Implicit Feedback

Accurate personalized headline generation hinges on precisely capturing user interests from historical behaviors. However, existing methods neglect personalized-irrelevant click noise in entire historical clickstreams, which may lead to hallucinated headlines that deviate from genuine user preferences. In this paper, we reveal the detrimental impact of click noise on personalized generation quality through rigorous analysis in both user and news dimensions. Based on these insights, we propose a novel Personalized Headline Generation framework via Denoising Fake Interests from Implicit Feedback (PHG-DIF). PHG-DIF first employs dual-stage filtering to effectively remove clickstream noise, identified by short dwell times and abnormal click bursts, and then leverages multi-level temporal fusion to dynamically model users' evolving and multi-faceted interests for precise profiling. Moreover, we release DT-PENS, a new benchmark dataset comprising the click behavior of 1,000 carefully curated users and nearly 10,000 annotated personalized headlines with historical dwell time annotations. Extensive experiments demonstrate that PHG-DIF substantially mitigates the adverse effects of click noise and significantly improves headline quality, achieving state-of-the-art (SOTA) results on DT-PENS. Our framework implementation and dataset are available at https://github.com/liukejin-up/PHG-DIF.

NutriGen: Personalized Meal Plan Generator Leveraging Large Language Models to Enhance Dietary and Nutritional Adherence

Maintaining a balanced diet is essential for overall health, yet many individuals struggle with meal planning due to nutritional complexity, time constraints, and lack of dietary knowledge. Personalized food recommendations can help address these challenges by tailoring meal plans to individual preferences, habits, and dietary restrictions. However, existing dietary recommendation systems often lack adaptability, fail to consider real-world constraints such as food ingredient availability, and require extensive user input, making them impractical for sustainable and scalable daily use. To address these limitations, we introduce NutriGen, a framework based on large language models (LLM) designed to generate personalized meal plans that align with user-defined dietary preferences and constraints. By building a personalized nutrition database and leveraging prompt engineering, our approach enables LLMs to incorporate reliable nutritional references like the USDA nutrition database while maintaining flexibility and ease-of-use. We demonstrate that LLMs have strong potential in generating accurate and user-friendly food recommendations, addressing key limitations in existing dietary recommendation systems by providing structured, practical, and scalable meal plans. Our evaluation shows that Llama 3.1 8B and GPT-3.5 Turbo achieve the lowest percentage errors of 1.55\% and 3.68\%, respectively, producing meal plans that closely align with user-defined caloric targets while minimizing deviation and improving precision. Additionally, we compared the performance of DeepSeek V3 against several established models to evaluate its potential in personalized nutrition planning.

Lifelong Personalized Low-Rank Adaptation of Large Language Models for Recommendation

We primarily focus on the field of large language models (LLMs) for recommendation, which has been actively explored recently and poses a significant challenge in effectively enhancing recommender systems with logical reasoning abilities and open-world knowledge. Current mainstream efforts mainly center around injecting personalized information from recommendation models into LLMs by customizing input templates or aligning representations between semantic and recommendation spaces at the prediction layer. However, they face three significant limitations: (1) LoRA is mostly used as a core component in existing works, but personalization is not well established in LoRA parameters as the LoRA matrix shared by every user may not cater to different users' characteristics, leading to suboptimal performance. (2) Although lifelong personalized behavior sequences are ideal for personalization, their use raises effectiveness and efficiency issues since LLMs require escalating training and inference time to extend text lengths. (3) Existing approaches aren't scalable for large datasets due to training efficiency constraints. Thus, LLMs only see a small fraction of the datasets (e.g., less than 10%) instead of the whole datasets, limiting their exposure to the full training space. To address these problems, we propose RecLoRA. This model incorporates a Personalized LoRA module that maintains independent LoRAs for different users and a Long-Short Modality Retriever that retrieves different history lengths for different modalities, significantly improving performance while adding minimal time cost. Furthermore, we design a Few2Many Learning Strategy, using a conventional recommendation model as a lens to magnify small training spaces to full spaces. Extensive experiments on public datasets demonstrate the efficacy of our RecLoRA compared to existing baseline models.

AI in Pharma for Personalized Sequential Decision-Making: Methods, Applications and Opportunities

In the pharmaceutical industry, the use of artificial intelligence (AI) has seen consistent growth over the past decade. This rise is attributed to major advancements in statistical machine learning methodologies, computational capabilities and the increased availability of large datasets. AI techniques are applied throughout different stages of drug development, ranging from drug discovery to post-marketing benefit-risk assessment. Kolluri et al. provided a review of several case studies that span these stages, featuring key applications such as protein structure prediction, success probability estimation, subgroup identification, and AI-assisted clinical trial monitoring. From a regulatory standpoint, there was a notable uptick in submissions incorporating AI components in 2021. The most prevalent therapeutic areas leveraging AI were oncology (27%), psychiatry (15%), gastroenterology (12%), and neurology (11%). The paradigm of personalized or precision medicine has gained significant traction in recent research, partly due to advancements in AI techniques hamburg2010path. This shift has had a transformative impact on the pharmaceutical industry. Departing from the traditional "one-size-fits-all" model, personalized medicine incorporates various individual factors, such as environmental conditions, lifestyle choices, and health histories, to formulate customized treatment plans. By utilizing sophisticated machine learning algorithms, clinicians and researchers are better equipped to make informed decisions in areas such as disease prevention, diagnosis, and treatment selection, thereby optimizing health outcomes for each individual.

UQABench: Evaluating User Embedding for Prompting LLMs in Personalized Question Answering

Large language models (LLMs) achieve remarkable success in natural language processing (NLP). In practical scenarios like recommendations, as users increasingly seek personalized experiences, it becomes crucial to incorporate user interaction history into the context of LLMs to enhance personalization. However, from a practical utility perspective, user interactions' extensive length and noise present challenges when used directly as text prompts. A promising solution is to compress and distill interactions into compact embeddings, serving as soft prompts to assist LLMs in generating personalized responses. Although this approach brings efficiency, a critical concern emerges: Can user embeddings adequately capture valuable information and prompt LLMs? To address this concern, we propose \name, a benchmark designed to evaluate the effectiveness of user embeddings in prompting LLMs for personalization. We establish a fair and standardized evaluation process, encompassing pre-training, fine-tuning, and evaluation stages. To thoroughly evaluate user embeddings, we design three dimensions of tasks: sequence understanding, action prediction, and interest perception. These evaluation tasks cover the industry's demands in traditional recommendation tasks, such as improving prediction accuracy, and its aspirations for LLM-based methods, such as accurately understanding user interests and enhancing the user experience. We conduct extensive experiments on various state-of-the-art methods for modeling user embeddings. Additionally, we reveal the scaling laws of leveraging user embeddings to prompt LLMs. The benchmark is available online.

LettinGo: Explore User Profile Generation for Recommendation System

User profiling is pivotal for recommendation systems, as it transforms raw user interaction data into concise and structured representations that drive personalized recommendations. While traditional embedding-based profiles lack interpretability and adaptability, recent advances with large language models (LLMs) enable text-based profiles that are semantically richer and more transparent. However, existing methods often adhere to fixed formats that limit their ability to capture the full diversity of user behaviors. In this paper, we introduce LettinGo, a novel framework for generating diverse and adaptive user profiles. By leveraging the expressive power of LLMs and incorporating direct feedback from downstream recommendation tasks, our approach avoids the rigid constraints imposed by supervised fine-tuning (SFT). Instead, we employ Direct Preference Optimization (DPO) to align the profile generator with task-specific performance, ensuring that the profiles remain adaptive and effective. LettinGo operates in three stages: (1) exploring diverse user profiles via multiple LLMs, (2) evaluating profile quality based on their impact in recommendation systems, and (3) aligning the profile generation through pairwise preference data derived from task performance. Experimental results demonstrate that our framework significantly enhances recommendation accuracy, flexibility, and contextual awareness. This work enhances profile generation as a key innovation for next-generation recommendation systems.

Evaluating Podcast Recommendations with Profile-Aware LLM-as-a-Judge

Evaluating personalized recommendations remains a central challenge, especially in long-form audio domains like podcasts, where traditional offline metrics suffer from exposure bias and online methods such as A/B testing are costly and operationally constrained. In this paper, we propose a novel framework that leverages Large Language Models (LLMs) as offline judges to assess the quality of podcast recommendations in a scalable and interpretable manner. Our two-stage profile-aware approach first constructs natural-language user profiles distilled from 90 days of listening history. These profiles summarize both topical interests and behavioral patterns, serving as compact, interpretable representations of user preferences. Rather than prompting the LLM with raw data, we use these profiles to provide high-level, semantically rich context-enabling the LLM to reason more effectively about alignment between a user's interests and recommended episodes. This reduces input complexity and improves interpretability. The LLM is then prompted to deliver fine-grained pointwise and pairwise judgments based on the profile-episode match. In a controlled study with 47 participants, our profile-aware judge matched human judgments with high fidelity and outperformed or matched a variant using raw listening histories. The framework enables efficient, profile-aware evaluation for iterative testing and model selection in recommender systems.

MentalArena: Self-play Training of Language Models for Diagnosis and Treatment of Mental Health Disorders

Mental health disorders are one of the most serious diseases in the world. Most people with such a disease lack access to adequate care, which highlights the importance of training models for the diagnosis and treatment of mental health disorders. However, in the mental health domain, privacy concerns limit the accessibility of personalized treatment data, making it challenging to build powerful models. In this paper, we introduce MentalArena, a self-play framework to train language models by generating domain-specific personalized data, where we obtain a better model capable of making a personalized diagnosis and treatment (as a therapist) and providing information (as a patient). To accurately model human-like mental health patients, we devise Symptom Encoder, which simulates a real patient from both cognition and behavior perspectives. To address intent bias during patient-therapist interactions, we propose Symptom Decoder to compare diagnosed symptoms with encoded symptoms, and dynamically manage the dialogue between patient and therapist according to the identified deviations. We evaluated MentalArena against 6 benchmarks, including biomedicalQA and mental health tasks, compared to 6 advanced models. Our models, fine-tuned on both GPT-3.5 and Llama-3-8b, significantly outperform their counterparts, including GPT-4o. We hope that our work can inspire future research on personalized care. Code is available in https://github.com/Scarelette/MentalArena/tree/main

Can LLM be a Personalized Judge?

Ensuring that large language models (LLMs) reflect diverse user values and preferences is crucial as their user bases expand globally. It is therefore encouraging to see the growing interest in LLM personalization within the research community. However, current works often rely on the LLM-as-a-Judge approach for evaluation without thoroughly examining its validity. In this paper, we investigate the reliability of LLM-as-a-Personalized-Judge, asking LLMs to judge user preferences based on personas. Our findings suggest that directly applying LLM-as-a-Personalized-Judge is less reliable than previously assumed, showing low and inconsistent agreement with human ground truth. The personas typically used are often overly simplistic, resulting in low predictive power. To address these issues, we introduce verbal uncertainty estimation into the LLM-as-a-Personalized-Judge pipeline, allowing the model to express low confidence on uncertain judgments. This adjustment leads to much higher agreement (above 80%) on high-certainty samples for binary tasks. Through human evaluation, we find that the LLM-as-a-Personalized-Judge achieves comparable performance to third-party humans evaluation and even surpasses human performance on high-certainty samples. Our work indicates that certainty-enhanced LLM-as-a-Personalized-Judge offers a promising direction for developing more reliable and scalable methods for evaluating LLM personalization.

MIRACLE: Towards Personalized Dialogue Generation with Latent-Space Multiple Personal Attribute Control

Personalized dialogue systems aim to endow the chatbot agent with more anthropomorphic traits for human-like interactions. Previous approaches have explored explicitly user profile modeling using text descriptions, implicit derivation of user embeddings, or utilizing handicraft prompts for ChatGPT-like models. However, textual personas are limited in describing multi-faceted attributes (e.g., language style, inner character nuances), implicit embedding suffers from personality sparsity, and handicraft prompts lack fine-grained and stable controllability. Hence, these approaches may struggle with complex personalized dialogue generation tasks that require generating controllable responses with multiple personal attributes. To this end, we propose \textsc{Miracle}, a novel personalized dialogue generation method through MultIple PeRsonal Attributes Control within Latent-Space Energy-based Models. ttributes Control within Latent-Space Energy-based Models. Specifically, our approach first disentangles complex personality into multi-faceted attributes. Subsequently, we employ a conditional variational auto-encoder to align with the dense personalized responses within a latent joint attribute space. We have also tailored a dedicated energy function and customized the ordinary differential equations sampling method to offer flexible attribute composition and precise attribute control. Extensive experiments demonstrate that Miracle outperforms several strong baselines in terms of personality controllability and response generation quality. Our dataset and code are available at https://github.com/LZY-the-boys/MIRACLE

SleepCoT: A Lightweight Personalized Sleep Health Model via Chain-of-Thought Distillation

We present a novel approach to personalized sleep health management using few-shot Chain-of-Thought (CoT) distillation, enabling small-scale language models (> 2B parameters) to rival the performance of large language models (LLMs) in specialized health domains. Our method simultaneously distills problem-solving strategies, long-tail expert knowledge, and personalized recommendation capabilities from larger models into more efficient, compact models. Unlike existing systems, our approach offers three key functionalities: generating personalized sleep health recommendations, supporting user-specific follow-up inquiries, and providing responses to domain-specific knowledge questions. We focus on sleep health due to its measurability via wearable devices and its impact on overall well-being. Our experimental setup, involving GPT-4o for data synthesis, Qwen-max for instruction set creation, and Qwen2.5 1.5B for model distillation, demonstrates significant improvements over baseline small-scale models in penalization, reasoning, and knowledge application. Experiments using 100 simulated sleep reports and 1,000 domain-specific questions shows our model achieves comparable performance to larger models while maintaining efficiency for real-world deployment. This research not only advances AI-driven health management but also provides a novel approach to leveraging LLM capabilities in resource-constrained environments, potentially enhancing the accessibility of personalized healthcare solutions.

Teaching Language Models to Evolve with Users: Dynamic Profile Modeling for Personalized Alignment

Personalized alignment is essential for enabling large language models (LLMs) to engage effectively in user-centric dialogue. While recent prompt-based and offline optimization methods offer preliminary solutions, they fall short in cold-start scenarios and long-term personalization due to their inherently static and shallow designs. In this work, we introduce the Reinforcement Learning for Personalized Alignment (RLPA) framework, in which an LLM interacts with a simulated user model to iteratively infer and refine user profiles through dialogue. The training process is guided by a dual-level reward structure: the Profile Reward encourages accurate construction of user representations, while the Response Reward incentivizes generation of responses consistent with the inferred profile. We instantiate RLPA by fine-tuning Qwen-2.5-3B-Instruct, resulting in Qwen-RLPA, which achieves state-of-the-art performance in personalized dialogue. Empirical evaluations demonstrate that Qwen-RLPA consistently outperforms prompting and offline fine-tuning baselines, and even surpasses advanced commercial models such as Claude-3.5 and GPT-4o. Further analysis highlights Qwen-RLPA's robustness in reconciling conflicting user preferences, sustaining long-term personalization and delivering more efficient inference compared to recent reasoning-focused LLMs. These results emphasize the potential of dynamic profile inference as a more effective paradigm for building personalized dialogue systems.

Bold but Cautious: Unlocking the Potential of Personalized Federated Learning through Cautiously Aggressive Collaboration

Personalized federated learning (PFL) reduces the impact of non-independent and identically distributed (non-IID) data among clients by allowing each client to train a personalized model when collaborating with others. A key question in PFL is to decide which parameters of a client should be localized or shared with others. In current mainstream approaches, all layers that are sensitive to non-IID data (such as classifier layers) are generally personalized. The reasoning behind this approach is understandable, as localizing parameters that are easily influenced by non-IID data can prevent the potential negative effect of collaboration. However, we believe that this approach is too conservative for collaboration. For example, for a certain client, even if its parameters are easily influenced by non-IID data, it can still benefit by sharing these parameters with clients having similar data distribution. This observation emphasizes the importance of considering not only the sensitivity to non-IID data but also the similarity of data distribution when determining which parameters should be localized in PFL. This paper introduces a novel guideline for client collaboration in PFL. Unlike existing approaches that prohibit all collaboration of sensitive parameters, our guideline allows clients to share more parameters with others, leading to improved model performance. Additionally, we propose a new PFL method named FedCAC, which employs a quantitative metric to evaluate each parameter's sensitivity to non-IID data and carefully selects collaborators based on this evaluation. Experimental results demonstrate that FedCAC enables clients to share more parameters with others, resulting in superior performance compared to state-of-the-art methods, particularly in scenarios where clients have diverse distributions.

Personalized Resource Allocation in Wireless Networks: An AI-Enabled and Big Data-Driven Multi-Objective Optimization

The design and optimization of wireless networks have mostly been based on strong mathematical and theoretical modeling. Nonetheless, as novel applications emerge in the era of 5G and beyond, unprecedented levels of complexity will be encountered in the design and optimization of the network. As a result, the use of Artificial Intelligence (AI) is envisioned for wireless network design and optimization due to the flexibility and adaptability it offers in solving extremely complex problems in real-time. One of the main future applications of AI is enabling user-level personalization for numerous use cases. AI will revolutionize the way we interact with computers in which computers will be able to sense commands and emotions from humans in a non-intrusive manner, making the entire process transparent to users. By leveraging this capability, and accelerated by the advances in computing technologies, wireless networks can be redesigned to enable the personalization of network services to the user level in real-time. While current wireless networks are being optimized to achieve a predefined set of quality requirements, the personalization technology advocated in this article is supported by an intelligent big data-driven layer designed to micro-manage the scarce network resources. This layer provides the intelligence required to decide the necessary service quality that achieves the target satisfaction level for each user. Due to its dynamic and flexible design, personalized networks are expected to achieve unprecedented improvements in optimizing two contradicting objectives in wireless networks: saving resources and improving user satisfaction levels.

Personalized Preference Fine-tuning of Diffusion Models

RLHF techniques like DPO can significantly improve the generation quality of text-to-image diffusion models. However, these methods optimize for a single reward that aligns model generation with population-level preferences, neglecting the nuances of individual users' beliefs or values. This lack of personalization limits the efficacy of these models. To bridge this gap, we introduce PPD, a multi-reward optimization objective that aligns diffusion models with personalized preferences. With PPD, a diffusion model learns the individual preferences of a population of users in a few-shot way, enabling generalization to unseen users. Specifically, our approach (1) leverages a vision-language model (VLM) to extract personal preference embeddings from a small set of pairwise preference examples, and then (2) incorporates the embeddings into diffusion models through cross attention. Conditioning on user embeddings, the text-to-image models are fine-tuned with the DPO objective, simultaneously optimizing for alignment with the preferences of multiple users. Empirical results demonstrate that our method effectively optimizes for multiple reward functions and can interpolate between them during inference. In real-world user scenarios, with as few as four preference examples from a new user, our approach achieves an average win rate of 76\% over Stable Cascade, generating images that more accurately reflect specific user preferences.

Personalized Audiobook Recommendations at Spotify Through Graph Neural Networks

In the ever-evolving digital audio landscape, Spotify, well-known for its music and talk content, has recently introduced audiobooks to its vast user base. While promising, this move presents significant challenges for personalized recommendations. Unlike music and podcasts, audiobooks, initially available for a fee, cannot be easily skimmed before purchase, posing higher stakes for the relevance of recommendations. Furthermore, introducing a new content type into an existing platform confronts extreme data sparsity, as most users are unfamiliar with this new content type. Lastly, recommending content to millions of users requires the model to react fast and be scalable. To address these challenges, we leverage podcast and music user preferences and introduce 2T-HGNN, a scalable recommendation system comprising Heterogeneous Graph Neural Networks (HGNNs) and a Two Tower (2T) model. This novel approach uncovers nuanced item relationships while ensuring low latency and complexity. We decouple users from the HGNN graph and propose an innovative multi-link neighbor sampler. These choices, together with the 2T component, significantly reduce the complexity of the HGNN model. Empirical evaluations involving millions of users show significant improvement in the quality of personalized recommendations, resulting in a +46% increase in new audiobooks start rate and a +23% boost in streaming rates. Intriguingly, our model's impact extends beyond audiobooks, benefiting established products like podcasts.

Preference Discerning with LLM-Enhanced Generative Retrieval

Sequential recommendation systems aim to provide personalized recommendations for users based on their interaction history. To achieve this, they often incorporate auxiliary information, such as textual descriptions of items and auxiliary tasks, like predicting user preferences and intent. Despite numerous efforts to enhance these models, they still suffer from limited personalization. To address this issue, we propose a new paradigm, which we term preference discerning. In preference dscerning, we explicitly condition a generative sequential recommendation system on user preferences within its context. To this end, we generate user preferences using Large Language Models (LLMs) based on user reviews and item-specific data. To evaluate preference discerning capabilities of sequential recommendation systems, we introduce a novel benchmark that provides a holistic evaluation across various scenarios, including preference steering and sentiment following. We assess current state-of-the-art methods using our benchmark and show that they struggle to accurately discern user preferences. Therefore, we propose a new method named Mender (Multimodal Preference discerner), which improves upon existing methods and achieves state-of-the-art performance on our benchmark. Our results show that Mender can be effectively guided by human preferences even though they have not been observed during training, paving the way toward more personalized sequential recommendation systems. We will open-source the code and benchmarks upon publication.

Know Me, Respond to Me: Benchmarking LLMs for Dynamic User Profiling and Personalized Responses at Scale

Large Language Models (LLMs) have emerged as personalized assistants for users across a wide range of tasks -- from offering writing support to delivering tailored recommendations or consultations. Over time, the interaction history between a user and an LLM can provide extensive information about an individual's traits and preferences. However, open questions remain on how well LLMs today can effectively leverage such history to (1) internalize the user's inherent traits and preferences, (2) track how the user profiling and preferences evolve over time, and (3) generate personalized responses accordingly in new scenarios. In this work, we introduce the PERSONAMEM benchmark. PERSONAMEM features curated user profiles with over 180 simulated user-LLM interaction histories, each containing up to 60 sessions of multi-turn conversations across 15 real-world tasks that require personalization. Given an in-situ user query, i.e. query issued by the user from the first-person perspective, we evaluate LLM chatbots' ability to identify the most suitable response according to the current state of the user's profile. We observe that current LLMs still struggle to recognize the dynamic evolution in users' profiles over time through direct prompting approaches. As a consequence, LLMs often fail to deliver responses that align with users' current situations and preferences, with frontier models such as GPT-4.1, o4-mini, GPT-4.5, o1, or Gemini-2.0 achieving only around 50% overall accuracy, suggesting room for improvement. We hope that PERSONAMEM, along with the user profile and conversation simulation pipeline, can facilitate future research in the development of truly user-aware chatbots. Code and data are available at github.com/bowen-upenn/PersonaMem.

Generative Recommendation: Towards Next-generation Recommender Paradigm

Recommender systems typically retrieve items from an item corpus for personalized recommendations. However, such a retrieval-based recommender paradigm faces two limitations: 1) the human-generated items in the corpus might fail to satisfy the users' diverse information needs, and 2) users usually adjust the recommendations via inefficient passive feedback, e.g., clicks. Nowadays, AI-Generated Content (AIGC) has revealed significant success, offering the potential to overcome these limitations: 1) generative AI can produce personalized items to satisfy users' information needs, and 2) the newly emerged large language models significantly reduce the efforts of users to precisely express information needs via natural language instructions. In this light, the boom of AIGC points the way towards the next-generation recommender paradigm with two new objectives: 1) generating personalized content through generative AI, and 2) integrating user instructions to guide content generation. To this end, we propose a novel Generative Recommender paradigm named GeneRec, which adopts an AI generator to personalize content generation and leverages user instructions. Specifically, we pre-process users' instructions and traditional feedback via an instructor to output the generation guidance. Given the guidance, we instantiate the AI generator through an AI editor and an AI creator to repurpose existing items and create new items. Eventually, GeneRec can perform content retrieval, repurposing, and creation to satisfy users' information needs. Besides, to ensure the trustworthiness of the generated items, we emphasize various fidelity checks. Moreover, we provide a roadmap to envision future developments of GeneRec and several domain-specific applications of GeneRec with potential research tasks. Lastly, we study the feasibility of implementing AI editor and AI creator on micro-video generation.

Automatic Personalized Impression Generation for PET Reports Using Large Language Models

In this study, we aimed to determine if fine-tuned large language models (LLMs) can generate accurate, personalized impressions for whole-body PET reports. Twelve language models were trained on a corpus of PET reports using the teacher-forcing algorithm, with the report findings as input and the clinical impressions as reference. An extra input token encodes the reading physician's identity, allowing models to learn physician-specific reporting styles. Our corpus comprised 37,370 retrospective PET reports collected from our institution between 2010 and 2022. To identify the best LLM, 30 evaluation metrics were benchmarked against quality scores from two nuclear medicine (NM) physicians, with the most aligned metrics selecting the model for expert evaluation. In a subset of data, model-generated impressions and original clinical impressions were assessed by three NM physicians according to 6 quality dimensions (3-point scale) and an overall utility score (5-point scale). Each physician reviewed 12 of their own reports and 12 reports from other physicians. Bootstrap resampling was used for statistical analysis. Of all evaluation metrics, domain-adapted BARTScore and PEGASUSScore showed the highest Spearman's rank correlations (0.568 and 0.563) with physician preferences. Based on these metrics, the fine-tuned PEGASUS model was selected as the top LLM. When physicians reviewed PEGASUS-generated impressions in their own style, 89% were considered clinically acceptable, with a mean utility score of 4.08 out of 5. Physicians rated these personalized impressions as comparable in overall utility to the impressions dictated by other physicians (4.03, P=0.41). In conclusion, personalized impressions generated by PEGASUS were clinically useful, highlighting its potential to expedite PET reporting.

Personalized Safety in LLMs: A Benchmark and A Planning-Based Agent Approach

Large language models (LLMs) typically generate identical or similar responses for all users given the same prompt, posing serious safety risks in high-stakes applications where user vulnerabilities differ widely. Existing safety evaluations primarily rely on context-independent metrics - such as factuality, bias, or toxicity - overlooking the fact that the same response may carry divergent risks depending on the user's background or condition. We introduce personalized safety to fill this gap and present PENGUIN - a benchmark comprising 14,000 scenarios across seven sensitive domains with both context-rich and context-free variants. Evaluating six leading LLMs, we demonstrate that personalized user information significantly improves safety scores by 43.2%, confirming the effectiveness of personalization in safety alignment. However, not all context attributes contribute equally to safety enhancement. To address this, we develop RAISE - a training-free, two-stage agent framework that strategically acquires user-specific background. RAISE improves safety scores by up to 31.6% over six vanilla LLMs, while maintaining a low interaction cost of just 2.7 user queries on average. Our findings highlight the importance of selective information gathering in safety-critical domains and offer a practical solution for personalizing LLM responses without model retraining. This work establishes a foundation for safety research that adapts to individual user contexts rather than assuming a universal harm standard.

Perpetuating Misogyny with Generative AI: How Model Personalization Normalizes Gendered Harm

Open-source text-to-image (TTI) pipelines have become dominant in the landscape of AI-generated visual content, driven by technological advances that enable users to personalize models through adapters tailored to specific tasks. While personalization methods such as LoRA offer unprecedented creative opportunities, they also facilitate harmful practices, including the generation of non-consensual deepfakes and the amplification of misogynistic or hypersexualized content. This study presents an exploratory sociotechnical analysis of CivitAI, the most active platform for sharing and developing open-source TTI models. Drawing on a dataset of more than 40 million user-generated images and over 230,000 models, we find a disproportionate rise in not-safe-for-work (NSFW) content and a significant number of models intended to mimic real individuals. We also observe a strong influence of internet subcultures on the tools and practices shaping model personalizations and resulting visual media. In response to these findings, we contextualize the emergence of exploitative visual media through feminist and constructivist perspectives on technology, emphasizing how design choices and community dynamics shape platform outcomes. Building on this analysis, we propose interventions aimed at mitigating downstream harm, including improved content moderation, rethinking tool design, and establishing clearer platform policies to promote accountability and consent.

Hi Sheldon! Creating Deep Personalized Characters from TV Shows

Imagine an interesting multimodal interactive scenario that you can see, hear, and chat with an AI-generated digital character, who is capable of behaving like Sheldon from The Big Bang Theory, as a DEEP copy from appearance to personality. Towards this fantastic multimodal chatting scenario, we propose a novel task, named Deep Personalized Character Creation (DPCC): creating multimodal chat personalized characters from multimodal data such as TV shows. Specifically, given a single- or multi-modality input (text, audio, video), the goal of DPCC is to generate a multi-modality (text, audio, video) response, which should be well-matched the personality of a specific character such as Sheldon, and of high quality as well. To support this novel task, we further collect a character centric multimodal dialogue dataset, named Deep Personalized Character Dataset (DPCD), from TV shows. DPCD contains character-specific multimodal dialogue data of ~10k utterances and ~6 hours of audio/video per character, which is around 10 times larger compared to existing related datasets.On DPCD, we present a baseline method for the DPCC task and create 5 Deep personalized digital Characters (DeepCharacters) from Big Bang TV Shows. We conduct both subjective and objective experiments to evaluate the multimodal response from DeepCharacters in terms of characterization and quality. The results demonstrates that, on our collected DPCD dataset, the proposed baseline can create personalized digital characters for generating multimodal response.Our collected DPCD dataset, the code of data collection and our baseline will be published soon.

USER-VLM 360: Personalized Vision Language Models with User-aware Tuning for Social Human-Robot Interactions

The integration of vision-language models into robotic systems constitutes a significant advancement in enabling machines to interact with their surroundings in a more intuitive manner. While VLMs offer rich multimodal reasoning, existing approaches lack user-specific adaptability, often relying on generic interaction paradigms that fail to account for individual behavioral, contextual, or socio-emotional nuances. When customization is attempted, ethical concerns arise from unmitigated biases in user data, risking exclusion or unfair treatment. To address these dual challenges, we propose User-VLM 360{\deg}, a holistic framework integrating multimodal user modeling with bias-aware optimization. Our approach features: (1) user-aware tuning that adapts interactions in real time using visual-linguistic signals; (2) bias mitigation via preference optimization; and (3) curated 360{\deg} socio-emotive interaction datasets annotated with demographic, emotion, and relational metadata. Evaluations across eight benchmarks demonstrate state-of-the-art results: +35.3% F1 in personalized VQA, +47.5% F1 in facial features understanding, 15% bias reduction, and 30X speedup over baselines. Ablation studies confirm component efficacy, and deployment on the Pepper robot validates real-time adaptability across diverse users. We open-source parameter-efficient 3B/10B models and an ethical verification framework for responsible adaptation.

Foundation Cures Personalization: Recovering Facial Personalized Models' Prompt Consistency

Facial personalization represents a crucial downstream task in the domain of text-to-image generation. To preserve identity fidelity while ensuring alignment with user-defined prompts, current mainstream frameworks for facial personalization predominantly employ identity embedding mechanisms to associate identity information with textual embeddings. However, our experiments show that identity embeddings compromise the effectiveness of other tokens within the prompt, thereby hindering high prompt consistency, particularly when prompts involve multiple facial attributes. Moreover, previous works overlook the fact that their corresponding foundation models hold great potential to generate faces aligning to prompts well and can be easily leveraged to cure these ill-aligned attributes in personalized models. Building upon these insights, we propose FreeCure, a training-free framework that harnesses the intrinsic knowledge from the foundation models themselves to improve the prompt consistency of personalization models. First, by extracting cross-attention and semantic maps from the denoising process of foundation models, we identify easily localized attributes (e.g., hair, accessories, etc). Second, we enhance multiple attributes in the outputs of personalization models through a novel noise-blending strategy coupled with an inversion-based process. Our approach offers several advantages: it eliminates the need for training; it effectively facilitates the enhancement for a wide array of facial attributes in a non-intrusive manner; and it can be seamlessly integrated into existing popular personalization models. FreeCure has demonstrated significant improvements in prompt consistency across a diverse set of state-of-the-art facial personalization models while maintaining the integrity of original identity fidelity.

EdgeWisePersona: A Dataset for On-Device User Profiling from Natural Language Interactions

This paper introduces a novel dataset and evaluation benchmark designed to assess and improve small language models deployable on edge devices, with a focus on user profiling from multi-session natural language interactions in smart home environments. At the core of the dataset are structured user profiles, each defined by a set of routines - context-triggered, repeatable patterns of behavior that govern how users interact with their home systems. Using these profiles as input, a large language model (LLM) generates corresponding interaction sessions that simulate realistic, diverse, and context-aware dialogues between users and their devices. The primary task supported by this dataset is profile reconstruction: inferring user routines and preferences solely from interactions history. To assess how well current models can perform this task under realistic conditions, we benchmarked several state-of-the-art compact language models and compared their performance against large foundation models. Our results show that while small models demonstrate some capability in reconstructing profiles, they still fall significantly short of large models in accurately capturing user behavior. This performance gap poses a major challenge - particularly because on-device processing offers critical advantages, such as preserving user privacy, minimizing latency, and enabling personalized experiences without reliance on the cloud. By providing a realistic, structured testbed for developing and evaluating behavioral modeling under these constraints, our dataset represents a key step toward enabling intelligent, privacy-respecting AI systems that learn and adapt directly on user-owned devices.

Using Sequences of Life-events to Predict Human Lives

Over the past decade, machine learning has revolutionized computers' ability to analyze text through flexible computational models. Due to their structural similarity to written language, transformer-based architectures have also shown promise as tools to make sense of a range of multi-variate sequences from protein-structures, music, electronic health records to weather-forecasts. We can also represent human lives in a way that shares this structural similarity to language. From one perspective, lives are simply sequences of events: People are born, visit the pediatrician, start school, move to a new location, get married, and so on. Here, we exploit this similarity to adapt innovations from natural language processing to examine the evolution and predictability of human lives based on detailed event sequences. We do this by drawing on arguably the most comprehensive registry data in existence, available for an entire nation of more than six million individuals across decades. Our data include information about life-events related to health, education, occupation, income, address, and working hours, recorded with day-to-day resolution. We create embeddings of life-events in a single vector space showing that this embedding space is robust and highly structured. Our models allow us to predict diverse outcomes ranging from early mortality to personality nuances, outperforming state-of-the-art models by a wide margin. Using methods for interpreting deep learning models, we probe the algorithm to understand the factors that enable our predictions. Our framework allows researchers to identify new potential mechanisms that impact life outcomes and associated possibilities for personalized interventions.

CoGenesis: A Framework Collaborating Large and Small Language Models for Secure Context-Aware Instruction Following

With the advancement of language models (LMs), their exposure to private data is increasingly inevitable, and their deployment (especially for smaller ones) on personal devices, such as PCs and smartphones, has become a prevailing trend. In contexts laden with user information, enabling models to both safeguard user privacy and execute commands efficiently emerges as an essential research imperative. In this paper, we propose CoGenesis, a collaborative generation framework integrating large (hosted on cloud infrastructure) and small models (deployed on local devices) to address privacy concerns logically. Initially, we design a pipeline to create personalized writing instruction datasets enriched with extensive context details as the testbed of this research issue. Subsequently, we introduce two variants of CoGenesis based on sketch and logits respectively. Our experimental findings, based on our synthesized dataset and two additional open-source datasets, indicate that: 1) Large-scale models perform well when provided with user context but struggle in the absence of such context. 2) While specialized smaller models fine-tuned on the synthetic dataset show promise, they still lag behind their larger counterparts. 3) Our CoGenesis framework, utilizing mixed-scale models, showcases competitive performance, providing a feasible solution to privacy issues.

Personalized Dialogue Generation with Diversified Traits

Endowing a dialogue system with particular personality traits is essential to deliver more human-like conversations. However, due to the challenge of embodying personality via language expression and the lack of large-scale persona-labeled dialogue data, this research problem is still far from well-studied. In this paper, we investigate the problem of incorporating explicit personality traits in dialogue generation to deliver personalized dialogues. To this end, firstly, we construct PersonalDialog, a large-scale multi-turn dialogue dataset containing various traits from a large number of speakers. The dataset consists of 20.83M sessions and 56.25M utterances from 8.47M speakers. Each utterance is associated with a speaker who is marked with traits like Age, Gender, Location, Interest Tags, etc. Several anonymization schemes are designed to protect the privacy of each speaker. This large-scale dataset will facilitate not only the study of personalized dialogue generation, but also other researches on sociolinguistics or social science. Secondly, to study how personality traits can be captured and addressed in dialogue generation, we propose persona-aware dialogue generation models within the sequence to sequence learning framework. Explicit personality traits (structured by key-value pairs) are embedded using a trait fusion module. During the decoding process, two techniques, namely persona-aware attention and persona-aware bias, are devised to capture and address trait-related information. Experiments demonstrate that our model is able to address proper traits in different contexts. Case studies also show interesting results for this challenging research problem.

Stylebreeder: Exploring and Democratizing Artistic Styles through Text-to-Image Models

Text-to-image models are becoming increasingly popular, revolutionizing the landscape of digital art creation by enabling highly detailed and creative visual content generation. These models have been widely employed across various domains, particularly in art generation, where they facilitate a broad spectrum of creative expression and democratize access to artistic creation. In this paper, we introduce STYLEBREEDER, a comprehensive dataset of 6.8M images and 1.8M prompts generated by 95K users on Artbreeder, a platform that has emerged as a significant hub for creative exploration with over 13M users. We introduce a series of tasks with this dataset aimed at identifying diverse artistic styles, generating personalized content, and recommending styles based on user interests. By documenting unique, user-generated styles that transcend conventional categories like 'cyberpunk' or 'Picasso,' we explore the potential for unique, crowd-sourced styles that could provide deep insights into the collective creative psyche of users worldwide. We also evaluate different personalization methods to enhance artistic expression and introduce a style atlas, making these models available in LoRA format for public use. Our research demonstrates the potential of text-to-image diffusion models to uncover and promote unique artistic expressions, further democratizing AI in art and fostering a more diverse and inclusive artistic community. The dataset, code and models are available at https://stylebreeder.github.io under a Public Domain (CC0) license.