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Aug 20

AIMI: Leveraging Future Knowledge and Personalization in Sparse Event Forecasting for Treatment Adherence

Adherence to prescribed treatments is crucial for individuals with chronic conditions to avoid costly or adverse health outcomes. For certain patient groups, intensive lifestyle interventions are vital for enhancing medication adherence. Accurate forecasting of treatment adherence can open pathways to developing an on-demand intervention tool, enabling timely and personalized support. With the increasing popularity of smartphones and wearables, it is now easier than ever to develop and deploy smart activity monitoring systems. However, effective forecasting systems for treatment adherence based on wearable sensors are still not widely available. We close this gap by proposing Adherence Forecasting and Intervention with Machine Intelligence (AIMI). AIMI is a knowledge-guided adherence forecasting system that leverages smartphone sensors and previous medication history to estimate the likelihood of forgetting to take a prescribed medication. A user study was conducted with 27 participants who took daily medications to manage their cardiovascular diseases. We designed and developed CNN and LSTM-based forecasting models with various combinations of input features and found that LSTM models can forecast medication adherence with an accuracy of 0.932 and an F-1 score of 0.936. Moreover, through a series of ablation studies involving convolutional and recurrent neural network architectures, we demonstrate that leveraging known knowledge about future and personalized training enhances the accuracy of medication adherence forecasting. Code available: https://github.com/ab9mamun/AIMI.

AssertionBench: A Benchmark to Evaluate Large-Language Models for Assertion Generation

Assertions have been the de facto collateral for simulation-based and formal verification of hardware designs for over a decade. The quality of hardware verification, \ie, detection and diagnosis of corner-case design bugs, is critically dependent on the quality of the assertions. There has been a considerable amount of research leveraging a blend of data-driven statistical analysis and static analysis to generate high-quality assertions from hardware design source code and design execution trace data. Despite such concerted effort, all prior research struggles to scale to industrial-scale large designs, generates too many low-quality assertions, often fails to capture subtle and non-trivial design functionality, and does not produce any easy-to-comprehend explanations of the generated assertions to understand assertions' suitability to different downstream validation tasks. Recently, with the advent of Large-Language Models (LLMs), there has been a widespread effort to leverage prompt engineering to generate assertions. However, there is little effort to quantitatively establish the effectiveness and suitability of various LLMs for assertion generation. In this paper, we present AssertionBench, a novel benchmark to evaluate LLMs' effectiveness for assertion generation quantitatively. AssertioBench contains 100 curated Verilog hardware designs from OpenCores and formally verified assertions for each design generated from GoldMine and HARM. We use AssertionBench to compare state-of-the-art LLMs to assess their effectiveness in inferring functionally correct assertions for hardware designs. Our experiments demonstrate how LLMs perform relative to each other, the benefits of using more in-context exemplars in generating a higher fraction of functionally correct assertions, and the significant room for improvement for LLM-based assertion generators.

AsserT5: Test Assertion Generation Using a Fine-Tuned Code Language Model

Writing good software tests can be challenging, therefore approaches that support developers are desirable. While generating complete tests automatically is such an approach commonly proposed in research, developers may already have specific test scenarios in mind and thus just require help in selecting the most suitable test assertions for these scenarios. This can be done using deep learning models to predict assertions for given test code. Prior research on assertion generation trained these models specifically for the task, raising the question how much the use of larger models pre-trained on code that have emerged since then can improve their performance. In particular, while abstracting identifiers has been shown to improve specifically trained models, it remains unclear whether this also generalises to models pre-trained on non-abstracted code. Finally, even though prior work demonstrated high accuracy it remains unclear how this translates into the effectiveness of the assertions at their intended application -- finding faults. To shed light on these open questions, in this paper we propose AsserT5, a new model based on the pre-trained CodeT5 model, and use this to empirically study assertion generation. We find that the abstraction and the inclusion of the focal method are useful also for a fine-tuned pre-trained model, resulting in test assertions that match the ground truth assertions precisely in up to 59.5\% of cases, more than twice as precise as prior models. However, evaluation on real bugs from the Defects4J dataset shows that out of 138 bugs detectable with assertions in real-world projects, AsserT5 was only able to suggest fault-finding assertions for 33, indicating the need for further improvements.

KIC 4150611: A quadruply eclipsing heptuple star system with a g-mode period-spacing pattern Asteroseismic modelling of the g-mode period-spacing pattern

In this work, we aim to estimate the stellar parameters of the primary (Aa) by performing asteroseismic analysis on its period-spacing pattern. We use the C-3PO neural network to perform asteroseismic modelling of the g-mode period-spacing pattern of Aa, discussing the interplay of this information with external constraints from spectroscopy (T_{rm eff} and log(g)) and eclipse modelling (R). To estimate the level of uncertainty due to different frequency extraction and pattern identification processes, we consider four different variations on the period-spacing patterns. To better understand the correlations between and the uncertainty structure of our parameter estimates, we also employed a classical, parameter-based MCMC grid search on four different stellar grids. The best-fitting, externally constrained model to the period-spacing pattern arrives at estimates of the stellar properties for Aa of: M=1.51 pm 0.05 M_odot, X_c =0.43 pm 0.04, R=1.66 pm 0.1 R_odot, f_{rm ov}=0.010, Omega_c=1.58 pm 0.01 d^{-1} with rigid rotation to within the measurement errors, log(T_{rm eff})=3.856 pm 0.008 dex, log(g)=4.18 pm 0.04 dex, and log(L)=0.809 pm 0.005 dex, which agree well with previous measurements from eclipse modelling, spectroscopy, and the Gaia DR3 luminosity. We find that the near-core properties of the best-fitting asteroseismic models are consistent with external constraints from eclipse modelling and spectroscopy. Aa appears to be a typical example of a gamma Dor star, fitting well within existing populations. We find that Aa is quasi-rigidly rotating to within the uncertainties, and note that the asteroseismic age estimate for Aa (1100 pm 100 Myr) is considerably older than the young (35 Myr) age implied by previous isochrone fits to the B binary in the literature. Our MCMC parameter-based grid-search agrees well with our pattern-modelling approach.

ASTER: Natural and Multi-language Unit Test Generation with LLMs

Implementing automated unit tests is an important but time-consuming activity in software development. To assist developers in this task, many techniques for automating unit test generation have been developed. However, despite this effort, usable tools exist for very few programming languages. Moreover, studies have found that automatically generated tests suffer poor readability and do not resemble developer-written tests. In this work, we present a rigorous investigation of how large language models (LLMs) can help bridge the gap. We describe a generic pipeline that incorporates static analysis to guide LLMs in generating compilable and high-coverage test cases. We illustrate how the pipeline can be applied to different programming languages, specifically Java and Python, and to complex software requiring environment mocking. We conducted an empirical study to assess the quality of the generated tests in terms of code coverage and test naturalness -- evaluating them on standard as well as enterprise Java applications and a large Python benchmark. Our results demonstrate that LLM-based test generation, when guided by static analysis, can be competitive with, and even outperform, state-of-the-art test-generation techniques in coverage achieved while also producing considerably more natural test cases that developers find easy to understand. We also present the results of a user study, conducted with 161 professional developers, that highlights the naturalness characteristics of the tests generated by our approach.

Zyxin is all you need: machine learning adherent cell mechanics

Cellular form and function emerge from complex mechanochemical systems within the cytoplasm. No systematic strategy currently exists to infer large-scale physical properties of a cell from its many molecular components. This is a significant obstacle to understanding biophysical processes such as cell adhesion and migration. Here, we develop a data-driven biophysical modeling approach to learn the mechanical behavior of adherent cells. We first train neural networks to predict forces generated by adherent cells from images of cytoskeletal proteins. Strikingly, experimental images of a single focal adhesion protein, such as zyxin, are sufficient to predict forces and generalize to unseen biological regimes. This protein field alone contains enough information to yield accurate predictions even if forces themselves are generated by many interacting proteins. We next develop two approaches - one explicitly constrained by physics, the other more agnostic - that help construct data-driven continuum models of cellular forces using this single focal adhesion field. Both strategies consistently reveal that cellular forces are encoded by two different length scales in adhesion protein distributions. Beyond adherent cell mechanics, our work serves as a case study for how to integrate neural networks in the construction of predictive phenomenological models in cell biology, even when little knowledge of the underlying microscopic mechanisms exist.

Colors and Dynamics of a Near-Sun Orbital Asteroid Family: 2021 PH27 and 2025 GN1

We observed the dynamically similar near-Sun asteroids 2021 PH27 and 2025 GN1 for their optical colors. These objects have the lowest known semi-major axes of any asteroids. 2021 PH27 has the largest general relativistic effects of any known solar system object. The small semi-major axis and very close passage to the Sun suggests the extreme thermal and gravitational environment should highly modify these asteroids' surfaces. From g', r', i' and z'-band imaging, we find the colors of 2021 PH27 to be between the two major asteroid types the S and C classes (g'-r'= 0.58 +- 0.02, r'-i'=0.12 +- 0.02 and i'-z'=-0.08 +- 0.05 mags). With a spectral slope of 6.8 +-0.03 percent per 100nm, 2021 PH27 is a X-type asteroid and requires albedo or spectral features to further identify its composition. We find the dynamically similar 2025 GN1 also has very similar colors (g'-r'=0.55 +-0.06 and r'-i'=0.14 +-0.04) as 2021 PH27, suggesting these objects are fragments from a once larger parent asteroid or 2021 PH27 is shedding material. The colors are not blue like some other near-Sun asteroids such as 3200 Phaethon that have been interpreted to be from the loss of reddening substances from the extreme temperatures. There is no evidence of activity or a large amplitude period for 2021 PH27, whereas 2025 GN1 might have a more significant rotational light curve. 2025 GN1 may have a very close encounter or hit Venus in about 2155 years and likely separated from 2021 PH27 in about the last 10 kyrs.

GUARD: Role-playing to Generate Natural-language Jailbreakings to Test Guideline Adherence of Large Language Models

The discovery of "jailbreaks" to bypass safety filters of Large Language Models (LLMs) and harmful responses have encouraged the community to implement safety measures. One major safety measure is to proactively test the LLMs with jailbreaks prior to the release. Therefore, such testing will require a method that can generate jailbreaks massively and efficiently. In this paper, we follow a novel yet intuitive strategy to generate jailbreaks in the style of the human generation. We propose a role-playing system that assigns four different roles to the user LLMs to collaborate on new jailbreaks. Furthermore, we collect existing jailbreaks and split them into different independent characteristics using clustering frequency and semantic patterns sentence by sentence. We organize these characteristics into a knowledge graph, making them more accessible and easier to retrieve. Our system of different roles will leverage this knowledge graph to generate new jailbreaks, which have proved effective in inducing LLMs to generate unethical or guideline-violating responses. In addition, we also pioneer a setting in our system that will automatically follow the government-issued guidelines to generate jailbreaks to test whether LLMs follow the guidelines accordingly. We refer to our system as GUARD (Guideline Upholding through Adaptive Role-play Diagnostics). We have empirically validated the effectiveness of GUARD on three cutting-edge open-sourced LLMs (Vicuna-13B, LongChat-7B, and Llama-2-7B), as well as a widely-utilized commercial LLM (ChatGPT). Moreover, our work extends to the realm of vision language models (MiniGPT-v2 and Gemini Vision Pro), showcasing GUARD's versatility and contributing valuable insights for the development of safer, more reliable LLM-based applications across diverse modalities.

Towards Automatic Translation of Machine Learning Visual Insights to Analytical Assertions

We present our vision for developing an automated tool capable of translating visual properties observed in Machine Learning (ML) visualisations into Python assertions. The tool aims to streamline the process of manually verifying these visualisations in the ML development cycle, which is critical as real-world data and assumptions often change post-deployment. In a prior study, we mined 54,070 Jupyter notebooks from Github and created a catalogue of 269 semantically related visualisation-assertion (VA) pairs. Building on this catalogue, we propose to build a taxonomy that organises the VA pairs based on ML verification tasks. The input feature space comprises of a rich source of information mined from the Jupyter notebooks -- visualisations, Python source code, and associated markdown text. The effectiveness of various AI models, including traditional NLP4Code models and modern Large Language Models, will be compared using established machine translation metrics and evaluated through a qualitative study with human participants. The paper also plans to address the challenge of extending the existing VA pair dataset with additional pairs from Kaggle and to compare the tool's effectiveness with commercial generative AI models like ChatGPT. This research not only contributes to the field of ML system validation but also explores novel ways to leverage AI for automating and enhancing software engineering practices in ML.

NutriGen: Personalized Meal Plan Generator Leveraging Large Language Models to Enhance Dietary and Nutritional Adherence

Maintaining a balanced diet is essential for overall health, yet many individuals struggle with meal planning due to nutritional complexity, time constraints, and lack of dietary knowledge. Personalized food recommendations can help address these challenges by tailoring meal plans to individual preferences, habits, and dietary restrictions. However, existing dietary recommendation systems often lack adaptability, fail to consider real-world constraints such as food ingredient availability, and require extensive user input, making them impractical for sustainable and scalable daily use. To address these limitations, we introduce NutriGen, a framework based on large language models (LLM) designed to generate personalized meal plans that align with user-defined dietary preferences and constraints. By building a personalized nutrition database and leveraging prompt engineering, our approach enables LLMs to incorporate reliable nutritional references like the USDA nutrition database while maintaining flexibility and ease-of-use. We demonstrate that LLMs have strong potential in generating accurate and user-friendly food recommendations, addressing key limitations in existing dietary recommendation systems by providing structured, practical, and scalable meal plans. Our evaluation shows that Llama 3.1 8B and GPT-3.5 Turbo achieve the lowest percentage errors of 1.55\% and 3.68\%, respectively, producing meal plans that closely align with user-defined caloric targets while minimizing deviation and improving precision. Additionally, we compared the performance of DeepSeek V3 against several established models to evaluate its potential in personalized nutrition planning.

Analyzing Semantic Faithfulness of Language Models via Input Intervention on Conversational Question Answering

Transformer-based language models have been shown to be highly effective for several NLP tasks. In this paper, we consider three transformer models, BERT, RoBERTa, and XLNet, in both small and large version, and investigate how faithful their representations are with respect to the semantic content of texts. We formalize a notion of semantic faithfulness, in which the semantic content of a text should causally figure in a model's inferences in question answering. We then test this notion by observing a model's behavior on answering questions about a story after performing two novel semantic interventions -- deletion intervention and negation intervention. While transformer models achieve high performance on standard question answering tasks, we show that they fail to be semantically faithful once we perform these interventions for a significant number of cases (~50% for deletion intervention, and ~20% drop in accuracy for negation intervention). We then propose an intervention-based training regime that can mitigate the undesirable effects for deletion intervention by a significant margin (from ~50% to ~6%). We analyze the inner-workings of the models to better understand the effectiveness of intervention-based training for deletion intervention. But we show that this training does not attenuate other aspects of semantic unfaithfulness such as the models' inability to deal with negation intervention or to capture the predicate-argument structure of texts. We also test InstructGPT, via prompting, for its ability to handle the two interventions and to capture predicate-argument structure. While InstructGPT models do achieve very high performance on predicate-argument structure task, they fail to respond adequately to our deletion and negation interventions.

NOTSOFAR-1 Challenge: New Datasets, Baseline, and Tasks for Distant Meeting Transcription

We introduce the first Natural Office Talkers in Settings of Far-field Audio Recordings (``NOTSOFAR-1'') Challenge alongside datasets and baseline system. The challenge focuses on distant speaker diarization and automatic speech recognition (DASR) in far-field meeting scenarios, with single-channel and known-geometry multi-channel tracks, and serves as a launch platform for two new datasets: First, a benchmarking dataset of 315 meetings, averaging 6 minutes each, capturing a broad spectrum of real-world acoustic conditions and conversational dynamics. It is recorded across 30 conference rooms, featuring 4-8 attendees and a total of 35 unique speakers. Second, a 1000-hour simulated training dataset, synthesized with enhanced authenticity for real-world generalization, incorporating 15,000 real acoustic transfer functions. The tasks focus on single-device DASR, where multi-channel devices always share the same known geometry. This is aligned with common setups in actual conference rooms, and avoids technical complexities associated with multi-device tasks. It also allows for the development of geometry-specific solutions. The NOTSOFAR-1 Challenge aims to advance research in the field of distant conversational speech recognition, providing key resources to unlock the potential of data-driven methods, which we believe are currently constrained by the absence of comprehensive high-quality training and benchmarking datasets.

Beyond the Imitation Game: Quantifying and extrapolating the capabilities of language models

Language models demonstrate both quantitative improvement and new qualitative capabilities with increasing scale. Despite their potentially transformative impact, these new capabilities are as yet poorly characterized. In order to inform future research, prepare for disruptive new model capabilities, and ameliorate socially harmful effects, it is vital that we understand the present and near-future capabilities and limitations of language models. To address this challenge, we introduce the Beyond the Imitation Game benchmark (BIG-bench). BIG-bench currently consists of 204 tasks, contributed by 442 authors across 132 institutions. Task topics are diverse, drawing problems from linguistics, childhood development, math, common-sense reasoning, biology, physics, social bias, software development, and beyond. BIG-bench focuses on tasks that are believed to be beyond the capabilities of current language models. We evaluate the behavior of OpenAI's GPT models, Google-internal dense transformer architectures, and Switch-style sparse transformers on BIG-bench, across model sizes spanning millions to hundreds of billions of parameters. In addition, a team of human expert raters performed all tasks in order to provide a strong baseline. Findings include: model performance and calibration both improve with scale, but are poor in absolute terms (and when compared with rater performance); performance is remarkably similar across model classes, though with benefits from sparsity; tasks that improve gradually and predictably commonly involve a large knowledge or memorization component, whereas tasks that exhibit "breakthrough" behavior at a critical scale often involve multiple steps or components, or brittle metrics; social bias typically increases with scale in settings with ambiguous context, but this can be improved with prompting.

Context Aware Grounded Teacher for Source Free Object Detection

We focus on the Source Free Object Detection (SFOD) problem, when source data is unavailable during adaptation, and the model must adapt to the unlabeled target domain. In medical imaging, several approaches have leveraged a semi-supervised student-teacher architecture to bridge domain discrepancy. Context imbalance in labeled training data and significant domain shifts between domains can lead to biased teacher models that produce inaccurate pseudolabels, degrading the student model's performance and causing a mode collapse. Class imbalance, particularly when one class significantly outnumbers another, leads to contextual bias. To tackle the problem of context bias and the significant performance drop of the student model in the SFOD setting, we introduce Grounded Teacher (GT) as a standard framework. In this study, we model contextual relationships using a dedicated relational context module and leverage it to mitigate inherent biases in the model. This approach enables us to apply augmentations to closely related classes, across and within domains, enhancing the performance of underrepresented classes while keeping the effect on dominant classes minimal. We further improve the quality of predictions by implementing an expert foundational branch to supervise the student model. We validate the effectiveness of our approach in mitigating context bias under the SFOD setting through experiments on three medical datasets supported by comprehensive ablation studies. All relevant resources, including preprocessed data, trained model weights, and code, are publicly available at this https://github.com/Tajamul21/Grounded_Teacher.

TITAN: Query-Token based Domain Adaptive Adversarial Learning

We focus on the source-free domain adaptive object detection (SF-DAOD) problem when source data is unavailable during adaptation and the model must adapt to an unlabeled target domain. The majority of approaches for the problem employ a self-supervised approach using a student-teacher (ST) framework where pseudo-labels are generated via a source-pretrained model for further fine-tuning. We observe that the performance of a student model often degrades drastically, due to the collapse of the teacher model, primarily caused by high noise in pseudo-labels, resulting from domain bias, discrepancies, and a significant domain shift across domains. To obtain reliable pseudo-labels, we propose a Target-based Iterative Query-Token Adversarial Network (TITAN), which separates the target images into two subsets: those similar to the source (easy) and those dissimilar (hard). We propose a strategy to estimate variance to partition the target domain. This approach leverages the insight that higher detection variances correspond to higher recall and greater similarity to the source domain. Also, we incorporate query-token-based adversarial modules into a student-teacher baseline framework to reduce the domain gaps between two feature representations. Experiments conducted on four natural imaging datasets and two challenging medical datasets have substantiated the superior performance of TITAN compared to existing state-of-the-art (SOTA) methodologies. We report an mAP improvement of +22.7, +22.2, +21.1, and +3.7 percent over the current SOTA on C2F, C2B, S2C, and K2C benchmarks, respectively.

Agent-X: Evaluating Deep Multimodal Reasoning in Vision-Centric Agentic Tasks

Deep reasoning is fundamental for solving complex tasks, especially in vision-centric scenarios that demand sequential, multimodal understanding. However, existing benchmarks typically evaluate agents with fully synthetic, single-turn queries, limited visual modalities, and lack a framework to assess reasoning quality over multiple steps as required in real-world settings. To address this, we introduce Agent-X, a large-scale benchmark for evaluating vision-centric agents multi-step and deep reasoning capabilities in real-world, multimodal settings. Agent- X features 828 agentic tasks with authentic visual contexts, including images, multi-image comparisons, videos, and instructional text. These tasks span six major agentic environments: general visual reasoning, web browsing, security and surveillance, autonomous driving, sports, and math reasoning. Our benchmark requires agents to integrate tool use with explicit, stepwise decision-making in these diverse settings. In addition, we propose a fine-grained, step-level evaluation framework that assesses the correctness and logical coherence of each reasoning step and the effectiveness of tool usage throughout the task. Our results reveal that even the best-performing models, including GPT, Gemini, and Qwen families, struggle to solve multi-step vision tasks, achieving less than 50% full-chain success. These findings highlight key bottlenecks in current LMM reasoning and tool-use capabilities and identify future research directions in vision-centric agentic reasoning models. Our data and code are publicly available at https://github.com/mbzuai-oryx/Agent-X

Evaluating Large Language Models on the GMAT: Implications for the Future of Business Education

The rapid evolution of artificial intelligence (AI), especially in the domain of Large Language Models (LLMs) and generative AI, has opened new avenues for application across various fields, yet its role in business education remains underexplored. This study introduces the first benchmark to assess the performance of seven major LLMs, OpenAI's models (GPT-3.5 Turbo, GPT-4, and GPT-4 Turbo), Google's models (PaLM 2, Gemini 1.0 Pro), and Anthropic's models (Claude 2 and Claude 2.1), on the GMAT, which is a key exam in the admission process for graduate business programs. Our analysis shows that most LLMs outperform human candidates, with GPT-4 Turbo not only outperforming the other models but also surpassing the average scores of graduate students at top business schools. Through a case study, this research examines GPT-4 Turbo's ability to explain answers, evaluate responses, identify errors, tailor instructions, and generate alternative scenarios. The latest LLM versions, GPT-4 Turbo, Claude 2.1, and Gemini 1.0 Pro, show marked improvements in reasoning tasks compared to their predecessors, underscoring their potential for complex problem-solving. While AI's promise in education, assessment, and tutoring is clear, challenges remain. Our study not only sheds light on LLMs' academic potential but also emphasizes the need for careful development and application of AI in education. As AI technology advances, it is imperative to establish frameworks and protocols for AI interaction, verify the accuracy of AI-generated content, ensure worldwide access for diverse learners, and create an educational environment where AI supports human expertise. This research sets the stage for further exploration into the responsible use of AI to enrich educational experiences and improve exam preparation and assessment methods.