Datasets:
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- dna
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- reasoning
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# Variant Effect Coding Dataset
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50,083 core variant entries from GPN-MSA study using ClinVar pathogenic variants and gnomAD benign variants (MAF>5%), split by chromosome (Chr 1-7,9-22,X,Y for train, Chr 8 for test) for pathogenic/benign classification.
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- dna
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- reasoning
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<h1 align="center">
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🧬 BioReason<br>Incentivizing Multimodal Biological Reasoning within a DNA-LLM Model
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</h1>
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<p align="center">
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<a href="https://www.arxiv.org/abs/2505.23579" target="_blank"><img src="https://img.shields.io/badge/arXiv-2505.23579-FF6B6B?style=for-the-badge&logo=arxiv&logoColor=white" alt="arXiv"></a>
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<a href="https://github.com/bowang-lab/BioReason"><img src="https://img.shields.io/badge/GitHub-Code-4A90E2?style=for-the-badge&logo=github&logoColor=white" alt="GitHub"></a>
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<a href="https://huggingface.co/collections/wanglab/bioreason-683cd17172a037a31d208f70"><img src="https://img.shields.io/badge/HuggingFace-Dataset-FFBF00?style=for-the-badge&logo=huggingface&logoColor=white" alt="HuggingFace Dataset"></a>
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</p>
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<br>
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# Variant Effect Coding Dataset
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50,083 core variant entries from GPN-MSA study using ClinVar pathogenic variants and gnomAD benign variants (MAF>5%), split by chromosome (Chr 1-7,9-22,X,Y for train, Chr 8 for test) for pathogenic/benign classification.
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